Detalhe da pesquisa
1.
Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity.
Nature
; 595(7866): 289-294, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34194041
2.
Sterile protection against human malaria by chemoattenuated PfSPZ vaccine.
Nature
; 542(7642): 445-449, 2017 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28199305
3.
Multidose Priming and Delayed Boosting Improve Plasmodium falciparum Sporozoite Vaccine Efficacy Against Heterologous P. falciparum Controlled Human Malaria Infection.
Clin Infect Dis
; 73(7): e2424-e2435, 2021 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32920641
4.
Safety, Tolerability, and Immunogenicity of Plasmodium falciparum Sporozoite Vaccine Administered by Direct Venous Inoculation to Infants and Young Children: Findings From an Age De-escalation, Dose-Escalation, Double-blind, Randomized Controlled Study in Western Kenya.
Clin Infect Dis
; 71(4): 1063-1071, 2020 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31555824
5.
Attenuated PfSPZ Vaccine induces strain-transcending T cells and durable protection against heterologous controlled human malaria infection.
Proc Natl Acad Sci U S A
; 114(10): 2711-2716, 2017 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28223498
6.
Dose-Dependent Infectivity of Aseptic, Purified, Cryopreserved Plasmodium falciparum 7G8 Sporozoites in Malaria-Naive Adults.
J Infect Dis
; 220(12): 1962-1966, 2019 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31419294
7.
Implementation of a Randomized, Placebo-Controlled Trial of Live Attenuated Malaria Sporozoite Vaccines in an Indonesian Military Study Population.
Am J Trop Med Hyg
; 110(5): 892-901, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38531102
8.
Safety and protective efficacy of PfSPZ Vaccine administered to HIV-negative and -positive Tanzanian adults.
J Clin Invest
; 134(6)2024 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38194272
9.
Innate immune activation restricts priming and protective efficacy of the radiation-attenuated PfSPZ malaria vaccine.
JCI Insight
; 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38687615
10.
Safety and Immunogenicity of Radiation-Attenuated PfSPZ Vaccine in Equatoguinean Infants, Children, and Adults.
Am J Trop Med Hyg
; 109(1): 138-146, 2023 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37160281
11.
Sporozoite immunization: innovative translational science to support the fight against malaria.
Expert Rev Vaccines
; 22(1): 964-1007, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37571809
12.
A First for Human Vaccinology: GMP Compliant Radiation Attenuation of Plasmodium falciparum Sporozoites for Production of a Vaccine Against Malaria.
Front Immunol
; 13: 851028, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35242146
13.
Plasmodium falciparum 7G8 challenge provides conservative prediction of efficacy of PfNF54-based PfSPZ Vaccine in Africa.
Nat Commun
; 13(1): 3390, 2022 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35697668
14.
A PfSPZ vaccine immunization regimen equally protective against homologous and heterologous controlled human malaria infection.
NPJ Vaccines
; 7(1): 100, 2022 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35999221
15.
Safety and efficacy of a three-dose regimen of Plasmodium falciparum sporozoite vaccine in adults during an intense malaria transmission season in Mali: a randomised, controlled phase 1 trial.
Lancet Infect Dis
; 22(3): 377-389, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34801112
16.
Increased levels of anti-PfCSP antibodies in post-pubertal females versus males immunized with PfSPZ Vaccine does not translate into increased protective efficacy.
Front Immunol
; 13: 1006716, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36389797
17.
Multi-Dose Priming Regimens of PfSPZ Vaccine: Safety and Efficacy against Controlled Human Malaria Infection in Equatoguinean Adults.
Am J Trop Med Hyg
; 2022 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35130487
18.
Immunogenicity and Protective Efficacy of Radiation-Attenuated and Chemo-Attenuated PfSPZ Vaccines in Equatoguinean Adults.
Am J Trop Med Hyg
; 104(1): 283-293, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33205741
19.
A double-blind, placebo-controlled phase 1/2a trial of the genetically attenuated malaria vaccine PfSPZ-GA1.
Sci Transl Med
; 12(544)2020 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32434847
20.
Advancing Global Health through Development and Clinical Trials Partnerships: A Randomized, Placebo-Controlled, Double-Blind Assessment of Safety, Tolerability, and Immunogenicity of PfSPZ Vaccine for Malaria in Healthy Equatoguinean Men.
Am J Trop Med Hyg
; 98(1): 308-318, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29141739