Nanomaterials as adsorbents for As(III) and As(V) removal from water: A review.

Freshwater demand will rise in the next couple of decades, with an increase in worldwide population growth and industrial development. The development activities, on one side, have increased the freshwater demand. However, the ground water has been degraded. Among the various organic and inorganic contaminants, arsenic is one of the most toxic elements. Arsenic contamination in ground waters is a major issue worldwide, especially in South and Southeast Asia. Various methods have been applied to provide a remedy to arsenic contamination, including adsorption, ion exchange, oxidation, coagulation-precipitation and filtration, and membrane filtration. Out of these methods, adsorption of As(III)/As(V) using nanomaterials and biopolymers has been used on a wide scale. The present review focuses on recently used nanomaterials and biopolymer composites for As(III)/As(V) sorptive removal. As(III)/As(V) adsorption mechanisms have been explored for various sorbents. The impacts of environmental factors such as pH and co-existing ions on As(III)/As(V) removal, have been discussed. Comparison of various nanosorbents and biopolymer composites for As(III)/As(V) adsorption and regeneration of exhausted materials has been included. Overall, this review will be useful to understand the sorption mechanisms involved in As(III)/As(V) removal by nanomaterials and biopolymer composites and their comparative sorption performances.

Plant extract mediated synthesis enhanced the functional properties of silver ferrite nanoparticles over chemical mediated synthesis.

In this study, the antibacterial, antioxidant and cytotoxicity behaviour of silver ferrite nanoparticles (AgFeO2 NPs) synthesized through chemical and green routes were compared. Green synthesis (Bio) of AgFeO2 NPs were prepared by precipitation method using Amaranthus blitum leaves extract as a reducing agent. Chemical synthesis (Che) of AgFeO2 NPs was mediated by sodium borohydride as a reducing agent. [AgFeO2 (Bio)] NPs showed reduced size, better monodispersity and surface area compared to [AgFeO2 (Che)] NPs. The results showed that synthesized NPs have better antibacterial activity against E. coli than S. aureus. In addition, 250 µg of AgFeO2 (Bio) and (Che) NPs showed antioxidant efficiency of 98 and 86%. The results showed that [AgFeO2 (Bio)] NPs showed lower cytotoxicity [AgFeO2 (Che)] NPs against human human embryonic kidney (HEK 293) cells. These results suggest that [AgFeO2 (Bio)] NPs have improved physicochemical properties thereby they can be used as an effective biocatalytic material in biotechnology.

Synthesis of Silver Nanoparticles and their Biomedical Applications - A Comprehensive Review.

Generally, silver is considered as a noble metal used for treating burn wound infections, open wounds and cuts. However, the emerging nanotechnology has made a remarkable impact by converting metallic silver into silver nanoparticles (AgNPs) for better applications. The advancement in technology has improved the synthesis of NPs using biological method instead of physical and chemical methods. Nonetheless, synthesizing AgNPs using biological sources is ecofriendly and cost effective. Till date, AgNPs are widely used as antibacterial agents; therefore, a novel idea is needed for the successful use of AgNPs as therapeutic agents to uncertain diseases and infections. In biomedicine, AgNPs possess significant advantages due to their physical and chemical versatility. Indeed, the toxicity concerns regarding AgNPs have created the need for non-toxic and ecofriendly approaches to produce AgNPs. The applications of AgNPs in nanogels, nanosolutions, silver based dressings and coating over medical devices are under progress. Still, an improvised version of AgNPs for extended applications in an ecofriendly manner is the need of the hour. Therefore, the present review emphasizes the synthesis methods, modes of action under dissipative conditions and the various biomedical applications of AgNPs in detail.

Photocatalytic degradation of naphthalene using calcined FeZnO/ PVA nanofibers.

Recently, the incorporation of metal oxide nanoparticles into polymers has gained great attention owing to their ample of applications. The green mediated synthesis Fe-doped ZnO nanoparticles have been incorporated into PVA nanofibers through electro spinning for the application of photocatalytic degradation. The PVA polymer concentration was optimized to obtain uniform fibers without beads. The Fe-doped ZnO nanofibers were characterized by various analyzing techniques. The results show that good physicochemical with high surface area, uniformity in fiber with an average diameter ranges from 150 to 300 and 50-200 nm for un-calcined and calcined Fe-doped ZnO nanofiber respectively. The photocatalytic activity of nanofibers was examined by the degradation of naphthalene. The efficiency was observed 96 and 81% for calcined and un-calcined nanofibers, respectively. The reusable efficacy of Fe-doped ZnO calcined nanofiber as a catalyst was studied. These studies corroborated that the calcined Fe-doped ZnO nanofiber as promising material for catalytic applications.

An enhancement of antimicrobial efficacy of biogenic and ceftriaxone-conjugated silver nanoparticles: green approach.

Of the various methods explored for the synthesis of nanoparticles, biogenesis of silver nanoparticles (AgNPs) received great attention due to their versatile properties. In this report, Daucus carota extract was used for the synthesis of AgNPs and ceftriaxone was conjugated with AgNPs to enhance their antimicrobial efficacy. The conjugated and unconjugated AgNPs were characterized by adopting UV-Vis spectroscopy, FTIR, AFM, DLS, and TEM, which revealed the SPR peak at 420 nm and spherical shaped nanoparticles of 20 nm size, respectively. The antimicrobial efficacies of the unconjugated AgNPs and ceftriaxone-conjugated AgNPs were tested against ceftriaxone-resistant human pathogens, Bacillus cereus, Staphylococcus aureus, Klebsiella pneumoniae, and Pseudomonas aeruginosa. The ceftriaxone-conjugated AgNPs showed high inhibitory action (23 mm) than the unconjugated AgNPs (18 mm) at the concentration of 50 µg/mL. Both the unconjugated and ceftriaxone-conjugated AgNPs were found to be non-toxic on EAC cells at 50 µg/mL. The dose-dependent cytotoxic activities were observed on increasing the concentration of the AgNPs. The ceftriaxone-conjugated AgNPs showed high activity than the unconjugated AgNPs. The enhanced activity could be useful to treat ceftriaxone-resistant human pathogens.

Conventional and nanotechniques for DNA methylation profiling.

DNA methylation is critical for gene silencing and is associated with the incidence of many diseases, including cancer. Underlying molecular mechanisms of human diseases and tissue-specific gene expression have been elucidated based on DNA methylation studies. This review highlights the advantages and drawbacks of various methylation screening techniques: blotting, genomic sequencing, bisulfite sequencing, methylation-specific PCR, methylated DNA immunoprecipitation, microarray analysis, matrix-assisted laser desorption ionization time-of-flight mass spectroscopy, nanowire transistor detection procedure, quantum dot-based nanoassay, single-molecule real-time detection, fluorimetric assay, electrochemical detection, and atomic force spectroscopy. The review provides insight for selecting a method or a combination of methods for DNA methylation analysis. Convergence of conventional and contemporary nanotechniques to enumerate methylation at specific CpG sites of oncogene would fill the gap in diagnosis of cancer.