Detalhe da pesquisa
1.
Design, synthesis, structure-activity relationship studies, and evaluation of novel GLS1 inhibitors.
Bioorg Med Chem Lett
; 87: 129266, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37011768
2.
Design and structural optimization of thiadiazole derivatives with potent GLS1 inhibitory activity.
Bioorg Med Chem Lett
; 93: 129438, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37549852
3.
Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis.
Bioorg Med Chem
; 90: 117370, 2023 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37311373
4.
Usefulness of the whole-body counter for infants and small children (BABYSCAN) as a risk communication tool after the Fukushima Daiichi nuclear power plant incident.
Proc Jpn Acad Ser B Phys Biol Sci
; 96(2): 70-78, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32037370
5.
Trypsin-induced aggregation of transthyretin Valine 30 variants associated with hereditary amyloidosis.
FEBS J
; 291(8): 1732-1743, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38273457
6.
Enzymatic activity of cGAS in the presence of three types of DNAs: limited cGAS stimulation by single-stranded HIV-1 SL2 DNA.
Biosci Rep
; 44(4)2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38530250
7.
Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma.
J Med Chem
; 2024 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38670538
8.
Hydrogen-bond network and pH sensitivity in human transthyretin.
J Synchrotron Radiat
; 20(Pt 6): 834-7, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24121323
9.
Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin.
J Med Chem
; 66(22): 15511-15523, 2023 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37910439
10.
Rafoxanide, a salicylanilide anthelmintic, interacts with human plasma protein transthyretin.
FEBS J
; 290(21): 5158-5170, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37522420
11.
Structural and mutational analyses of decarboxylated osteocalcin provide insight into its adiponectin-inducing activity.
FEBS Lett
; 597(11): 1479-1488, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36976525
12.
Structural characterization of a trapped folding intermediate of pyrrolidone carboxyl peptidase from a hyperthermophile.
Biochemistry
; 51(31): 6089-96, 2012 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22799522
13.
Hydrogen-bond network and pH sensitivity in transthyretin: Neutron crystal structure of human transthyretin.
J Struct Biol
; 177(2): 283-90, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22248451
14.
Neutron crystallographic analysis of the nucleotide-binding domain of Hsp72 in complex with ADP.
IUCrJ
; 9(Pt 5): 562-572, 2022 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36071806
15.
Chlorinated Naringenin Analogues as Potential Inhibitors of Transthyretin Amyloidogenesis.
J Med Chem
; 65(24): 16218-16233, 2022 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36472374
16.
Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding.
Biochemistry
; 49(1): 114-23, 2010 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19950966
17.
The crystal structure of the green tea polyphenol (-)-epigallocatechin gallate-transthyretin complex reveals a novel binding site distinct from the thyroxine binding site.
Biochemistry
; 49(29): 6104-14, 2010 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20565072
18.
Structural and thermodynamic characterization of the binding of isoliquiritigenin to the first bromodomain of BRD4.
FEBS J
; 286(9): 1656-1667, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30565859
19.
Allosteric modulation of the binding affinity between PQBP1 and the spliceosomal protein U5-15kD.
FEBS Lett
; 590(14): 2221-31, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27314904
20.
Effects of the stabilization of the molten globule state on the folding mechanism of alpha-lactalbumin: a study of a chimera of bovine and human alpha-lactalbumin.
Proteins
; 61(2): 356-65, 2005 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16121399