Detalhe da pesquisa
1.
RNA Oncological Therapeutics: Intracellular Hairpin RNA Assembly Enables MicroRNA-Triggered Anticancer Functionality.
J Am Chem Soc
; 146(2): 1346-1355, 2024 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38170469
2.
Hydrophobicity Tuning of Cationic Polyaspartamide Derivatives for Enhanced Antisense Oligonucleotide Delivery.
Bioconjug Chem
; 35(2): 125-131, 2024 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38290165
3.
Systemic single administration of anti-inflammatory microRNA 146a-5p loaded in polymeric nanomedicines with active targetability attenuates neointimal hyperplasia by controlling inflammation in injured arteries in a rat model.
FASEB J
; 36(9): e22486, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35929425
4.
Analysis of the sustained release ability of bevacizumab-loaded tetra-PEG gel.
Exp Eye Res
; 223: 109206, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35921961
5.
Dynamic Stabilization of Unit Polyion Complexes Incorporating Small Interfering RNA by Fine-Tuning of Cationic Block Length in Two-Branched Poly(ethylene glycol)-b-poly(l-lysine).
Biomacromolecules
; 23(1): 388-397, 2022 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34935361
6.
Block catiomer with flexible cationic segment enhances complexation with siRNA and the delivery performance in vitro.
Sci Technol Adv Mater
; 22(1): 850-863, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34658669
7.
Proliferation-associated long noncoding RNA, TMPO-AS1, is a potential therapeutic target for triple-negative breast cancer.
Cancer Sci
; 111(7): 2440-2450, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-32437068
8.
Installation of a Thermoswitchable Hydrophobic Domain into a Unimer Polyion Complex for Enhanced Cellular Uptake of siRNA.
Bioconjug Chem
; 31(5): 1320-1326, 2020 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32352276
9.
Noncovalent Stabilization of Vesicular Polyion Complexes with Chemically Modified/Single-Stranded Oligonucleotides and PEG-b-guanidinylated Polypeptides for Intracavity Encapsulation of Effector Enzymes Aimed at Cooperative Gene Knockdown.
Biomacromolecules
; 21(10): 4365-4376, 2020 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32924444
10.
Systemic Brain Delivery of Antisense Oligonucleotides across the Blood-Brain Barrier with a Glucose-Coated Polymeric Nanocarrier.
Angew Chem Int Ed Engl
; 59(21): 8173-8180, 2020 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31995252
11.
Self-Assembly of siRNA/PEG- b-Catiomer at Integer Molar Ratio into 100 nm-Sized Vesicular Polyion Complexes (siRNAsomes) for RNAi and Codelivery of Cargo Macromolecules.
J Am Chem Soc
; 141(8): 3699-3709, 2019 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30729777
12.
Tunable nonenzymatic degradability of N-substituted polyaspartamide main chain by amine protonation and alkyl spacer length in side chains for enhanced messenger RNA transfection efficiency.
Sci Technol Adv Mater
; 20(1): 105-115, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30787961
13.
Bundling mRNA Strands to Prepare Nano-Assemblies with Enhanced Stability Towards RNase for Inâ Vivo Delivery.
Angew Chem Int Ed Engl
; 58(33): 11360-11363, 2019 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31187576
14.
Tuned Density of Anti-Tissue Factor Antibody Fragment onto siRNA-Loaded Polyion Complex Micelles for Optimizing Targetability into Pancreatic Cancer Cells.
Biomacromolecules
; 19(6): 2320-2329, 2018 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29767505
15.
An Ethylenediamine-based Switch to Render the Polyzwitterion Cationic at Tumorous pH for Effective Tumor Accumulation of Coated Nanomaterials.
Angew Chem Int Ed Engl
; 57(18): 5057-5061, 2018 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29512262
16.
Polyplex Micelles with Phenylboronate/Gluconamide Cross-Linking in the Core Exerting Promoted Gene Transfection through Spatiotemporal Responsivity to Intracellular pH and ATP Concentration.
J Am Chem Soc
; 139(51): 18567-18575, 2017 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29188718
17.
siRNA-Loaded Polyion Complex Micelle Decorated with Charge-Conversional Polymer Tuned to Undergo Stepwise Response to Intra-Tumoral and Intra-Endosomal pHs for Exerting Enhanced RNAi Efficacy.
Biomacromolecules
; 17(1): 246-55, 2016 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26616636
18.
Recent Progress in the Endosomal Escape Mechanism and Chemical Structures of Polycations for Nucleic Acid Delivery.
Macromol Biosci
; 24(4): e2300366, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38226723
19.
Miscibility and ternary diagram of aqueous polyvinyl alcohols with different degrees of saponification.
Sci Rep
; 13(1): 8791, 2023 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37258599
20.
Molecular Weight-Dependent Diffusion, Biodistribution, and Clearance Behavior of Tetra-Armed Poly(ethylene glycol) Subcutaneously Injected into the Back of Mice.
ACS Macro Lett
; 12(4): 510-517, 2023 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37012585