Detalhe da pesquisa
1.
Antimony-Resistant Leishmania donovani Exploits miR-466i To Deactivate Host MyD88 for Regulating IL-10/IL-12 Levels during Early Hours of Infection.
J Immunol
; 195(6): 2731-42, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26283478
2.
Coccinia grandis (L.) Voigt Leaf Extract Exhibits Antileishmanial Effect Through Pro-inflammatory Response: An In Vitro Study.
Curr Microbiol
; 74(1): 59-67, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27796492
3.
Class II MHC/peptide interaction in Leishmania donovani infection: implications in vaccine design.
J Immunol
; 192(12): 5873-80, 2014 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24850723
4.
Imipramine exploits histone deacetylase 11 to increase the IL-12/IL-10 ratio in macrophages infected with antimony-resistant Leishmania donovani and clears organ parasites in experimental infection.
J Immunol
; 193(8): 4083-94, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25217162
5.
Antimony-resistant but not antimony-sensitive Leishmania donovani up-regulates host IL-10 to overexpress multidrug-resistant protein 1.
Proc Natl Acad Sci U S A
; 110(7): E575-82, 2013 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23341611
6.
TLR4-mediated activation of MyD88 signaling induces protective immune response and IL-10 down-regulation in Leishmania donovani infection.
Indian J Biochem Biophys
; 51(6): 531-41, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25823227
7.
Hyperlipidemia offers protection against Leishmania donovani infection: role of membrane cholesterol.
J Lipid Res
; 53(12): 2560-72, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23060454
8.
Asiaticoside induces tumour-necrosis-factor-α-mediated nitric oxide production to cure experimental visceral leishmaniasis caused by antimony-susceptible and -resistant Leishmania donovani strains.
J Antimicrob Chemother
; 67(4): 910-20, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22258930
9.
Complete protection against experimental visceral leishmaniasis with complete soluble antigen from attenuated Leishmania donovani promastigotes involves Th1-immunity and down-regulation of IL-10.
Eur J Immunol
; 39(8): 2146-60, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19593771
10.
Designing therapies against experimental visceral leishmaniasis by modulating the membrane fluidity of antigen-presenting cells.
Infect Immun
; 77(6): 2330-42, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19289510
11.
Sub-optimal dose of Sodium Antimony Gluconate (SAG)-diperoxovanadate combination clears organ parasites from BALB/c mice infected with antimony resistant Leishmania donovani by expanding antileishmanial T-cell repertoire and increasing IFN-gamma to IL-10 ratio.
Exp Parasitol
; 122(2): 145-54, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19422069
12.
Hybrid cell vaccination resolves Leishmania donovani infection by eliciting a strong CD8+ cytotoxic T-lymphocyte response with concomitant suppression of interleukin-10 (IL-10) but not IL-4 or IL-13.
Infect Immun
; 75(12): 5956-66, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17908806
13.
Protective inflammatory response against visceral leishmaniasis with potato tuber extract: A new approach of successful therapy.
Biomed Pharmacother
; 83: 1295-1302, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27567589
14.
TLR mediated GSK3ß activation suppresses CREB mediated IL-10 production to induce a protective immune response against murine visceral leishmaniasis.
Biochimie
; 107 Pt B: 235-46, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25223889
15.
Heterologous priming-boosting with DNA and vaccinia virus expressing kinetoplastid membrane protein-11 induces potent cellular immune response and confers protection against infection with antimony resistant and sensitive strains of Leishmania (Leishmania) donovani.
Vaccine
; 31(15): 1905-15, 2013 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23499564
16.
Imipramine is an orally active drug against both antimony sensitive and resistant Leishmania donovani clinical isolates in experimental infection.
PLoS Negl Trop Dis
; 6(12): e1987, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23301108
17.
Characterisation of antimony-resistant Leishmania donovani isolates: biochemical and biophysical studies and interaction with host cells.
Int J Parasitol
; 41(13-14): 1311-21, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21920365
18.
KMP-11 DNA immunization significantly protects against L. donovani infection but requires exogenous IL-12 as an adjuvant for comparable protection against L. major.
Vaccine
; 27(9): 1306-16, 2009 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-19162111
19.
Kinetoplastid membrane protein-11 DNA vaccination induces complete protection against both pentavalent antimonial-sensitive and -resistant strains of Leishmania donovani that correlates with inducible nitric oxide synthase activity and IL-4 generation: evidence for mixed Th1- and Th2-like responses in visceral leishmaniasis.
J Immunol
; 174(11): 7160-71, 2005 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15905560