Detalhe da pesquisa
1.
Design, synthesis, and screening of ortho-amino thiophene carboxamide derivatives on hepatocellular carcinomaas VEGFR-2Inhibitors.
J Enzyme Inhib Med Chem
; 33(1): 1472-1493, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30191744
2.
The structural requirements of histone deacetylase inhibitors: SAHA analogs modified at the C5 position display dual HDAC6/8 selectivity.
Bioorg Med Chem Lett
; 27(15): 3254-3258, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28648461
3.
Structural Requirements of Histone Deacetylase Inhibitors: SAHA Analogs Modified on the Hydroxamic Acid.
Arch Pharm (Weinheim)
; 349(5): 373-82, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27062198
4.
Chemically modified mRNA beyond COVID-19: Potential preventive and therapeutic applications for targeting chronic diseases.
Biomed Pharmacother
; 145: 112385, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34915673
5.
The structural requirements of histone deacetylase inhibitors: C4-modified SAHA analogs display dual HDAC6/HDAC8 selectivity.
Eur J Med Chem
; 143: 1790-1806, 2018 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29150330
6.
Structural Requirements of HDAC Inhibitors: SAHA Analogues Modified at the C2 Position Display HDAC6/8 Selectivity.
ACS Med Chem Lett
; 8(3): 281-286, 2017 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28337317
7.
Largazole Analogues Embodying Radical Changes in the Depsipeptide Ring: Development of a More Selective and Highly Potent Analogue.
J Med Chem
; 59(23): 10642-10660, 2016 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27809521
8.
Development of an ELISA-Based HDAC Activity Assay for Characterization of Isoform-Selective Inhibitors.
J Biomol Screen
; 20(10): 1277-85, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26232305
9.
Mutagenesis studies of the 14 Å internal cavity of histone deacetylase 1: insights toward the acetate-escape hypothesis and selective inhibitor design.
J Med Chem
; 57(3): 642-50, 2014 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24405391
10.
Design, Synthesis, and Antitumor Evaluation of Novel Pyrazolo[3,4-d]pyrimidine Derivatives.
Sci Pharm
; 80(3): 531-45, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23008804