RESUMO
Prevalence rates of multiple sclerosis (MS) suggest an interrelationship between genetic and environmental factors, ranging worldwide.Objectives Clinical and epidemiological characterization of MS patients in João Pessoa, Paraíba city.Methods Study involving patients treated in five services in the city.Results It included 87 patients with MS, representing a prevalence of 12.0 cases/100,000 population, mainly women (77%) and white people (66.7%) with mean age of 43 years and average age of the first outbreak of 32.2 years. Motor symptoms (65.5%) and relapsing-remitting clinical form (78.2%) predominated; the average of the Expanded Disability Status Scale (EDSS) scores was 3.5 and 72% used a type of immunomodulatory drug. There was a positive correlation between the number of outbreaks and the duration of the disease with EDSS scores.Conclusions The prevalence of the disease is considered average. The clinical and epidemiological characteristics are in line with most similar Brazilian studies.
Assuntos
Esclerose Múltipla/epidemiologia , Adulto , Idade de Início , Brasil/epidemiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Esclerose Múltipla/etnologia , Prevalência , Estudos Retrospectivos , Fatores SocioeconômicosRESUMO
Prevalence rates of multiple sclerosis (MS) suggest an interrelationship between genetic and environmental factors, ranging worldwide.Objectives Clinical and epidemiological characterization of MS patients in João Pessoa, Paraíba city.Methods Study involving patients treated in five services in the city.Results It included 87 patients with MS, representing a prevalence of 12.0 cases/100,000 population, mainly women (77%) and white people (66.7%) with mean age of 43 years and average age of the first outbreak of 32.2 years. Motor symptoms (65.5%) and relapsing-remitting clinical form (78.2%) predominated; the average of the Expanded Disability Status Scale (EDSS) scores was 3.5 and 72% used a type of immunomodulatory drug. There was a positive correlation between the number of outbreaks and the duration of the disease with EDSS scores.Conclusions The prevalence of the disease is considered average. The clinical and epidemiological characteristics are in line with most similar Brazilian studies.
As taxas de prevalência da esclerose múltipla (EM) sugerem uma inter-relação entre fatores genéticos e ambientais, variando mundialmente.Objetivos Caracterização clínico-epidemiológica dos pacientes com EM na cidade de João Pessoa, Paraíba.Métodos O estudo envolveu pacientes atendidos em cinco serviços da cidade.Resultados Incluíram-se 87 pacientes com EM, que representou a prevalência de 12,0 casos/100.000 habitantes, com predomínio no sexo feminino (77%) e em brancos (66,7%), idade média de 43 anos e idade média do primeiro surto de 32,2 anos. Predominaram os sintomas motores (65,5%) e a forma clínica remitente-recorrente (78,2%); a média dos escores da Escala de Status de Incapacidade Expandida (EDSS) foi de 3,5 e 72% utilizava imunomoduladores. Houve correlação positiva entre o número de surtos e dos anos de doença com o escore EDSS.Conclusões A prevalência da doença no município é considerada média. As características clínico-epidemiológicas estão em consonância com a maioria dos estudos brasileiros semelhantes.