Detalhe da pesquisa
1.
Activation of the Calcium Receptor by Calcimimetic Agents Is Preserved Despite Modest Attenuating Effects of Hyperphosphatemia.
J Am Soc Nephrol
; 33(1): 201-212, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34732508
2.
Efficacy and Safety of Encaleret in Autosomal Dominant Hypocalcemia Type 1.
N Engl J Med
; 389(13): 1245-1247, 2023 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37754292
3.
Discovery and Development of Calcimimetic and Calcilytic Compounds.
Prog Med Chem
; 57(1): 1-86, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29680147
4.
Calcium-sensing receptor modulates cell adhesion and migration via integrins.
J Biol Chem
; 286(47): 40922-33, 2011 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21969374
5.
Autosomal Dominant Hypocalcemia Type 1: A Systematic Review.
J Bone Miner Res
; 37(10): 1926-1935, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35879818
6.
Calcilytic NPSP795 Increases Plasma Calcium and PTH in an Autosomal Dominant Hypocalcemia Type 1 Mouse Model.
JBMR Plus
; 4(10): e10402, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-33103030
7.
Phosphate acts directly on the calcium-sensing receptor to stimulate parathyroid hormone secretion.
Nat Commun
; 10(1): 4693, 2019 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31619668
8.
Treatment of Autosomal Dominant Hypocalcemia Type 1 With the Calcilytic NPSP795 (SHP635).
J Bone Miner Res
; 34(9): 1609-1618, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31063613
9.
ZT-031, a cyclized analog of parathyroid hormone(1-31) for the potential treatment of osteoporosis.
IDrugs
; 11(11): 827-40, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18988128
10.
Calcimimetic and calcilytic drugs for treating bone and mineral-related disorders.
Best Pract Res Clin Endocrinol Metab
; 27(3): 373-84, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23856266
11.
An orally active calcium-sensing receptor antagonist that transiently increases plasma concentrations of PTH and stimulates bone formation.
Bone
; 46(2): 534-42, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19786130
12.
Antagonists of the calcium receptor I. Amino alcohol-based parathyroid hormone secretagogues.
J Med Chem
; 52(13): 3982-93, 2009 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19492813
13.
Antagonists of the calcium receptor. 2. Amino alcohol-based parathyroid hormone secretagogues.
J Med Chem
; 52(21): 6599-605, 2009 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19821575
14.
Functional proteins involved in regulation of intracellular Ca(2+) for drug development: the extracellular calcium receptor and an innovative medical approach to control secondary hyperparathyroidism by calcimimetics.
J Pharmacol Sci
; 97(3): 355-60, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15781990
15.
Roles of Ca2+ and the Ca2+-sensing receptor (CASR) in the expression of inducible NOS (nitric oxide synthase)-2 and its BH4 (tetrahydrobiopterin)-dependent activation in cytokine-stimulated adult human astrocytes.
J Cell Biochem
; 96(2): 428-38, 2005 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16052472
16.
L-phenylalanine and NPS R-467 synergistically potentiate the function of the extracellular calcium-sensing receptor through distinct sites.
J Biol Chem
; 277(37): 33736-41, 2002 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-12114500
17.
Activation of the calcium receptor by a calcimimetic compound halts the progression of secondary hyperparathyroidism in uremic rats.
J Am Soc Nephrol
; 11(5): 903-911, 2000 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-10770968
18.
The Venus Fly Trap domain of the extracellular Ca2+ -sensing receptor is required for L-amino acid sensing.
J Biol Chem
; 279(50): 51739-44, 2004 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-15579475
19.
Physiological changes in extracellular calcium concentration directly control osteoblast function in the absence of calciotropic hormones.
Proc Natl Acad Sci U S A
; 101(14): 5140-5, 2004 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-15051872
20.
Pharmacodynamics of the type II calcimimetic compound cinacalcet HCl.
J Pharmacol Exp Ther
; 308(2): 627-35, 2004 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-14593085