RESUMO
In a retrospective study concerning the epidemiology of extended-spectrum beta-lactamase (ESBL) positive Enterobacteriaceae during 2007-2008 in the wards of the Carlo Poma hospital in Mantova, Mercurio surveillance software was used to detect alert microorganisms. Our objective was to link the epidemiological data with the type of patient and ward, and to assess the risk factors for such infections in particular nosocomial environments. The study enabled the change in the relative epidemiological data to be detected, and showed that such bacteria can be found almost throughout the hospital.
Assuntos
Proteínas de Bactérias/análise , Infecção Hospitalar/epidemiologia , Infecções por Enterobacteriaceae/epidemiologia , Enterobacteriaceae/isolamento & purificação , Hospitais Urbanos/estatística & dados numéricos , Resistência beta-Lactâmica , beta-Lactamases/análise , Adulto , Infecção Hospitalar/microbiologia , Enterobacteriaceae/enzimologia , Infecções por Enterobacteriaceae/microbiologia , Escherichia coli/enzimologia , Escherichia coli/isolamento & purificação , Infecções por Escherichia coli/epidemiologia , Infecções por Escherichia coli/microbiologia , Departamentos Hospitalares/estatística & dados numéricos , Humanos , Vigilância Imunológica , Recém-Nascido , Unidades de Terapia Intensiva Neonatal/estatística & dados numéricos , Itália/epidemiologia , Klebsiella/enzimologia , Klebsiella/isolamento & purificação , Infecções por Klebsiella/epidemiologia , Infecções por Klebsiella/microbiologia , Proteus/enzimologia , Proteus/isolamento & purificação , Infecções por Proteus/epidemiologia , Infecções por Proteus/microbiologia , Especificidade por SubstratoRESUMO
Today the sepsis represents a very important clinical entity. The Surviving Sepsis Campaign assessed an incidence of sepsis equal to 3 cases/1,000 inhabitants. In UK more than 30,000 cases of severe sepsis are calculated; furthermore the patients with sepsis are increasing worldwide (near 18 millions of cases per year). Because of its high mortality, the sepsis represents one of the main causes of death in the world, also in the developing countries where it causes near sixty percent of the total deaths yearly. The early diagnosis and therapy are very important elements for the outcome of the patients. The Authors present the results of the adoption in their hospital of a guidelines document for the management of the septic patient, that show a decrease of their mortality due to the early diagnosis and specific treatments.