Detalhe da pesquisa
1.
Human T cell generation is restored in CD3δ severe combined immunodeficiency through adenine base editing.
Cell
; 186(7): 1398-1416.e23, 2023 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36944331
2.
Massively parallel base editing to map variant effects in human hematopoiesis.
Cell
; 186(11): 2456-2474.e24, 2023 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37137305
3.
Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins.
Cell
; 185(2): 250-265.e16, 2022 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35021064
4.
Enhanced prime editing systems by manipulating cellular determinants of editing outcomes.
Cell
; 184(22): 5635-5652.e29, 2021 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34653350
5.
A Genetic Tool to Track Protein Aggregates and Control Prion Inheritance.
Cell
; 171(4): 966-979.e18, 2017 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29056345
6.
Cross-kingdom chemical communication drives a heritable, mutually beneficial prion-based transformation of metabolism.
Cell
; 158(5): 1083-1093, 2014 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25171409
7.
Post-translational modification-centric base editor screens to assess phosphorylation site functionality in high throughput.
Nat Methods
; 2024 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38684783
8.
In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice.
Nature
; 589(7843): 608-614, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33408413
9.
Base editing of haematopoietic stem cells rescues sickle cell disease in mice.
Nature
; 595(7866): 295-302, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34079130
10.
Self-delivering, chemically modified CRISPR RNAs for AAV co-delivery and genome editing in vivo.
Nucleic Acids Res
; 52(2): 977-997, 2024 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38033325
11.
In vivo HSC prime editing rescues sickle cell disease in a mouse model.
Blood
; 141(17): 2085-2099, 2023 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36800642
12.
Search-and-replace genome editing without double-strand breaks or donor DNA.
Nature
; 576(7785): 149-157, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31634902
13.
Disruption of HIV-1 co-receptors CCR5 and CXCR4 in primary human T cells and hematopoietic stem and progenitor cells using base editing.
Mol Ther
; 30(1): 130-144, 2022 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34737067
14.
Functional correction of CFTR mutations in human airway epithelial cells using adenine base editors.
Nucleic Acids Res
; 49(18): 10558-10572, 2021 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34520545
15.
In vivo somatic cell base editing and prime editing.
Mol Ther
; 29(11): 3107-3124, 2021 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34509669
16.
Pioneer cells established by the [SWI+] prion can promote dispersal and out-crossing in yeast.
PLoS Biol
; 15(11): e2003476, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-29135981
17.
Engineered virus-like particles for transient delivery of prime editor ribonucleoprotein complexes in vivo.
Nat Biotechnol
; 2024 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38191664
18.
Efficient prime editing in mouse brain, liver and heart with dual AAVs.
Nat Biotechnol
; 42(2): 253-264, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37142705
19.
Precise correction of a spectrum of ß-thalassemia mutations in coding and non-coding regions by base editors.
Mol Ther Nucleic Acids
; 35(2): 102205, 2024 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38817682
20.
Bone-marrow-homing lipid nanoparticles for genome editing in diseased and malignant haematopoietic stem cells.
Nat Nanotechnol
; 2024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38783058