Detalhe da pesquisa
1.
USP1-dependent nucleolytic expansion of PRIMPOL-generated nascent DNA strand discontinuities during replication stress.
Nucleic Acids Res
; 52(5): 2340-2354, 2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38180818
2.
Loss of MED12 activates the TGFß pathway to promote chemoresistance and replication fork stability in BRCA-deficient cells.
Nucleic Acids Res
; 49(22): 12855-12869, 2021 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34871431
3.
Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the resistance to multiple ATR inhibitors.
PLoS Genet
; 16(11): e1009176, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33137164
4.
Heterozygous RNF13 Gain-of-Function Variants Are Associated with Congenital Microcephaly, Epileptic Encephalopathy, Blindness, and Failure to Thrive.
Am J Hum Genet
; 104(1): 179-185, 2019 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30595371
5.
Genome-wide CRISPR synthetic lethality screen identifies a role for the ADP-ribosyltransferase PARP14 in DNA replication dynamics controlled by ATR.
Nucleic Acids Res
; 48(13): 7252-7264, 2020 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32542389
6.
FANCJ compensates for RAP80 deficiency and suppresses genomic instability induced by interstrand cross-links.
Nucleic Acids Res
; 48(16): 9161-9180, 2020 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32797166
7.
Error-prone replication of a 5-formylcytosine-mediated DNA-peptide cross-link in human cells.
J Biol Chem
; 294(27): 10619-10627, 2019 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31138652
8.
Heterozygous De Novo UBTF Gain-of-Function Variant Is Associated with Neurodegeneration in Childhood.
Am J Hum Genet
; 101(2): 267-273, 2017 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28777933
9.
PARP10 promotes cellular proliferation and tumorigenesis by alleviating replication stress.
Nucleic Acids Res
; 46(17): 8908-8916, 2018 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30032250
10.
Loss of E2F7 confers resistance to poly-ADP-ribose polymerase (PARP) inhibitors in BRCA2-deficient cells.
Nucleic Acids Res
; 46(17): 8898-8907, 2018 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30032296
11.
HUWE1 interacts with PCNA to alleviate replication stress.
EMBO Rep
; 17(6): 874-86, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27146073
12.
A novel role for the mono-ADP-ribosyltransferase PARP14/ARTD8 in promoting homologous recombination and protecting against replication stress.
Nucleic Acids Res
; 43(6): 3143-53, 2015 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25753673
13.
PARP10 deficiency manifests by severe developmental delay and DNA repair defect.
Neurogenetics
; 17(4): 227-232, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27624574
14.
The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance.
J Biol Chem
; 289(19): 13627-37, 2014 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24695737
15.
Role of Translesion DNA Synthesis in the Metabolism of Replication-associated Nascent Strand Gaps.
J Mol Biol
; 436(1): 168275, 2024 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37714300
16.
CRISPR knockout genome-wide screens identify the HELQ-RAD52 axis in regulating the repair of cisplatin-induced single stranded DNA gaps.
bioRxiv
; 2024 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38659927
17.
Mono-ADP-ribosylation by PARP10 and PARP14 in genome stability.
NAR Cancer
; 5(1): zcad009, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36814782
18.
Multi-step processing of replication stress-derived nascent strand DNA gaps by MRE11 and EXO1 nucleases.
Nat Commun
; 14(1): 6265, 2023 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37805499
19.
Erratum to: PARP10 deficiency manifests by severe developmental delay and DNA repair defect.
Neurogenetics
; 18(2): 119, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28190220
20.
The KU-PARP14 axis differentially regulates DNA resection at stalled replication forks by MRE11 and EXO1.
Nat Commun
; 13(1): 5063, 2022 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36030235