Pesquisa | Portal de Pesquisa da BVS

1.

SLC25A51 is a mammalian mitochondrial NAD⁺ transporter.

Luongo, Timothy S; Eller, Jared M; Lu, Mu-Jie; Niere, Marc; Raith, Fabio; Perry, Caroline; Bornstein, Marc R; Oliphint, Paul; Wang, Lin; McReynolds, Melanie R; Migaud, Marie E; Rabinowitz, Joshua D; Johnson, F Brad; Johnsson, Kai; Ziegler, Mathias; Cambronne, Xiaolu A; Baur, Joseph A.

Nature ; 588(7836): 174-179, 2020 12.

Artigo em Inglês | MEDLINE | ID: mdl-32906142

2.

Dynamics of SLC25A51 reveal preference for oxidized NAD⁺ and substrate led transport.

Goyal, Shivansh; Paspureddi, Akhilesh; Lu, Mu-Jie; Chan, Hsin-Ru; Lyons, Scott N; Wilson, Crystal N; Niere, Marc; Ziegler, Mathias; Cambronne, Xiaolu A.

EMBO Rep ; 24(10): e56596, 2023 10 09.

Artigo em Inglês | MEDLINE | ID: mdl-37575034

3.

Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity.

Houry, Dorothée; Raasakka, Arne; Ferrario, Eugenio; Niere, Marc; Bifulco, Ersilia; Kursula, Petri; Ziegler, Mathias.

J Struct Biol ; 215(3): 108004, 2023 09.

Artigo em Inglês | MEDLINE | ID: mdl-37495196

4.

Identification of evolutionary and kinetic drivers of NAD-dependent signaling.

Bockwoldt, Mathias; Houry, Dorothée; Niere, Marc; Gossmann, Toni I; Reinartz, Ines; Schug, Alexander; Ziegler, Mathias; Heiland, Ines.

Proc Natl Acad Sci U S A ; 116(32): 15957-15966, 2019 08 06.

Artigo em Inglês | MEDLINE | ID: mdl-31341085

5.

Keeping the balance in NAD metabolism.

Strømland, Øyvind; Niere, Marc; Nikiforov, Andrey A; VanLinden, Magali R; Heiland, Ines; Ziegler, Mathias.

Biochem Soc Trans ; 47(1): 119-130, 2019 02 28.

Artigo em Inglês | MEDLINE | ID: mdl-30626706

6.

NAD kinase controls animal NADP biosynthesis and is modulated via evolutionarily divergent calmodulin-dependent mechanisms.

Love, Nick R; Pollak, Nadine; Dölle, Christian; Niere, Marc; Chen, Yaoyao; Oliveri, Paola; Amaya, Enrique; Patel, Sandip; Ziegler, Mathias.

Proc Natl Acad Sci U S A ; 112(5): 1386-91, 2015 Feb 03.

Artigo em Inglês | MEDLINE | ID: mdl-25605906

7.

Generation, Release, and Uptake of the NAD Precursor Nicotinic Acid Riboside by Human Cells.

Kulikova, Veronika; Shabalin, Konstantin; Nerinovski, Kirill; Dölle, Christian; Niere, Marc; Yakimov, Alexander; Redpath, Philip; Khodorkovskiy, Mikhail; Migaud, Marie E; Ziegler, Mathias; Nikiforov, Andrey.

J Biol Chem ; 290(45): 27124-27137, 2015 Nov 06.

Artigo em Inglês | MEDLINE | ID: mdl-26385918

8.

Subcellular Distribution of NAD+ between Cytosol and Mitochondria Determines the Metabolic Profile of Human Cells.

VanLinden, Magali R; Dölle, Christian; Pettersen, Ina K N; Kulikova, Veronika A; Niere, Marc; Agrimi, Gennaro; Dyrstad, Sissel E; Palmieri, Ferdinando; Nikiforov, Andrey A; Tronstad, Karl Johan; Ziegler, Mathias.

J Biol Chem ; 290(46): 27644-59, 2015 Nov 13.

Artigo em Inglês | MEDLINE | ID: mdl-26432643

9.

ADP-ribosylhydrolase 3 (ARH3), not poly(ADP-ribose) glycohydrolase (PARG) isoforms, is responsible for degradation of mitochondrial matrix-associated poly(ADP-ribose).

Niere, Marc; Mashimo, Masato; Agledal, Line; Dölle, Christian; Kasamatsu, Atsushi; Kato, Jiro; Moss, Joel; Ziegler, Mathias.

J Biol Chem ; 287(20): 16088-102, 2012 May 11.

Artigo em Inglês | MEDLINE | ID: mdl-22433848

10.

Pathways and subcellular compartmentation of NAD biosynthesis in human cells: from entry of extracellular precursors to mitochondrial NAD generation.

Nikiforov, Andrey; Dölle, Christian; Niere, Marc; Ziegler, Mathias.

J Biol Chem ; 286(24): 21767-78, 2011 Jun 17.

Artigo em Inglês | MEDLINE | ID: mdl-21504897

11.

Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferases.

Lau, Corinna; Dölle, Christian; Gossmann, Toni I; Agledal, Line; Niere, Marc; Ziegler, Mathias.

J Biol Chem ; 285(24): 18868-76, 2010 Jun 11.

Artigo em Inglês | MEDLINE | ID: mdl-20388704

12.

Visualization of subcellular NAD pools and intra-organellar protein localization by poly-ADP-ribose formation.

Dölle, Christian; Niere, Marc; Lohndal, Emilia; Ziegler, Mathias.

Cell Mol Life Sci ; 67(3): 433-43, 2010 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-19902144

13.

Compartment-Specific Poly-ADP-Ribose Formation as a Biosensor for Subcellular NAD Pools.

VanLinden, Magali R; Niere, Marc; Nikiforov, Andrey A; Ziegler, Mathias; Dölle, Christian.

Methods Mol Biol ; 1608: 45-56, 2017.

Artigo em Inglês | MEDLINE | ID: mdl-28695502

14.

Combination of engineered neural cell adhesion molecules and GDF-5 for improved neurite extension in nerve guide concepts.

Niere, Marc; Braun, Bettina; Gass, Rea; Sturany, Sabine; Volkmer, Hansjürgen.

Biomaterials ; 27(18): 3432-40, 2006 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-16497371

15.

An organellar nα-acetyltransferase, naa60, acetylates cytosolic N termini of transmembrane proteins and maintains Golgi integrity.

Aksnes, Henriette; Van Damme, Petra; Goris, Marianne; Starheim, Kristian K; Marie, Michaël; Støve, Svein Isungset; Hoel, Camilla; Kalvik, Thomas Vikestad; Hole, Kristine; Glomnes, Nina; Furnes, Clemens; Ljostveit, Sonja; Ziegler, Mathias; Niere, Marc; Gevaert, Kris; Arnesen, Thomas.

Cell Rep ; 10(8): 1362-74, 2015 Mar 03.

Artigo em Inglês | MEDLINE | ID: mdl-25732826

16.

NAD+ surfaces again.

Ziegler, Mathias; Niere, Marc.

Biochem J ; 382(Pt 3): e5-6, 2004 Sep 15.

Artigo em Inglês | MEDLINE | ID: mdl-15352307

17.

The phosphate makes a difference: cellular functions of NADP.

Agledal, Line; Niere, Marc; Ziegler, Mathias.

Redox Rep ; 15(1): 2-10, 2010.

Artigo em Inglês | MEDLINE | ID: mdl-20196923

18.

The NMN/NaMN adenylyltransferase (NMNAT) protein family.

Lau, Corinna; Niere, Marc; Ziegler, Mathias.

Front Biosci (Landmark Ed) ; 14(2): 410-31, 2009 01 01.

Artigo em Inglês | MEDLINE | ID: mdl-19273075

19.

Functional localization of two poly(ADP-ribose)-degrading enzymes to the mitochondrial matrix.

Niere, Marc; Kernstock, Stefan; Koch-Nolte, Friedrich; Ziegler, Mathias.

Mol Cell Biol ; 28(2): 814-24, 2008 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-17991898

20.

NAD kinase levels control the NADPH concentration in human cells.

Pollak, Nadine; Niere, Marc; Ziegler, Mathias.

J Biol Chem ; 282(46): 33562-33571, 2007 Nov 16.

Artigo em Inglês | MEDLINE | ID: mdl-17855339

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