Detalhe da pesquisa
1.
The P5-type ATPase ATP13A1 modulates major histocompatibility complex I-related protein 1 (MR1)-mediated antigen presentation.
J Biol Chem
; 298(2): 101542, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34968463
2.
Genome-wide genetic screening with chemically mutagenized haploid embryonic stem cells.
Nat Chem Biol
; 13(1): 12-14, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27820796
3.
Gain- and Loss-of-Function Mutations in the Breast Cancer Gene GATA3 Result in Differential Drug Sensitivity.
PLoS Genet
; 12(9): e1006279, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27588951
4.
Synthetic lethal vulnerabilities of cancer.
Annu Rev Pharmacol Toxicol
; 55: 513-31, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25340932
5.
Megabase-scale deletion using CRISPR/Cas9 to generate a fully haploid human cell line.
Genome Res
; 24(12): 2059-65, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25373145
6.
Comparison of genetic variants in matched samples using thesaurus annotation.
Bioinformatics
; 32(5): 657-63, 2016 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26545822
7.
Functional genomics to uncover drug mechanism of action.
Nat Chem Biol
; 11(12): 942-8, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26575241
8.
Light-assisted small-molecule screening against protein kinases.
Nat Chem Biol
; 11(12): 952-4, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26457372
9.
A thesaurus of genetic variation for interrogation of repetitive genomic regions.
Nucleic Acids Res
; 43(10): e68, 2015 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25820428
10.
Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7.
Angew Chem Int Ed Engl
; 56(49): 15555-15559, 2017 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28976073
11.
A reversible gene trap collection empowers haploid genetics in human cells.
Nat Methods
; 10(10): 965-71, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24161985
12.
Targeting a cell state common to triple-negative breast cancers.
Mol Syst Biol
; 11(1): 789, 2015 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25699542
13.
TOPS: a versatile software tool for statistical analysis and visualization of combinatorial gene-gene and gene-drug interaction screens.
BMC Bioinformatics
; 15: 98, 2014 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24712852
14.
A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer.
Nat Chem Biol
; 7(11): 787-93, 2011 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21946274
15.
Regulation of monoubiquitinated PCNA by DUB autocleavage.
Nat Cell Biol
; 8(4): 339-47, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16531995
16.
Identification of oncostatin M as a STAT5-dependent mediator of bone marrow remodeling in KIT D816V-positive systemic mastocytosis.
Am J Pathol
; 178(5): 2344-56, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21457934
17.
p19(ARF) /p14(ARF) controls oncogenic functions of signal transducer and activator of transcription 3 in hepatocellular carcinoma.
Hepatology
; 54(1): 164-72, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21452288
18.
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB.
Nature
; 424(6950): 797-801, 2003 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-12917690
19.
Perturbation-Driven Entropy as a Source of Cancer Cell Heterogeneity.
Trends Cancer
; 6(6): 454-461, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32460001
20.
Quantitative genetic screening reveals a Ragulator-FLCN feedback loop that regulates the mTORC1 pathway.
Sci Signal
; 13(649)2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32934076