A single-set functional training program increases muscle power, improves functional fitness, and reduces pro-inflammatory cytokines in postmenopausal women: A randomized clinical trial.

Introduction: Aging can be associated with reduced muscle power, functional decline, and increased plasma concentrations of proinflammatory cytokines. Functional training (FT) can improve muscle power, functional fitness and reduce plasma cytokines. However, the functional training optimal volume required to produce these adaptations must be clarified. Our study analyzed the effects of multiple-set functional training (MSFT) and single-set functional training (SSFT) on postmenopausal women's muscle power, functional fitness, and inflammatory profile. Methods: Forty-three women were randomly allocated into three groups: multiple-set functional training (n = 16, age 64.13 ± 5.17), single-set functional training (n = 14, age 63.79 ± 4.88), and control group (CG, n = 13, age 64.62 ± 5.44). The bench press and squat exercises evaluated upper and lower limb muscle power. The following tests assessed functional fitness: putting on and taking off a T-shirt, gallon-jug shelf-transfer, standing up and walking around the house, five times sit-to-stand, and 400-m walk. Plasma cytokine (TNF-α, IL-6, and IL 10) concentrations were measured by flow cytometry. Results: Single-set functional training and multiple-set functional training increased upper and lower limbs muscle power and improved functional fitness, except for the putting on and taking off a T-shirt test. Multiple-set functional training reduced TNF-α and IL-6, while single-set functional training reduced only TNF-α. IL-10 was unaffected by exercise. Discussion: Single-set functional training and multiple-set functional training, therefore, promoted similar muscle power and functional fitness improvements over 24 weeks. Multiple-set functional training was more effective than single-set functional training, reducing both TNF and IL-6, while single-set functional training only decreased TNF-α.

Bodyweight and Combined Training Reduce Chronic Low-Grade Inflammation and Improve Functional Fitness of Postmenopausal Women.

Exercise is an important tool against the deleterious effects of aging. Among the possibilities of exercise, bodyweight training (BWT) has been highlighted in the last years as a safe option to improve the health of older people. We compared the effects of 24 weeks of BWT and combined training (CT) on low-grade systematic inflammation and functional fitness in postmenopausal women. For this, 40 women were allocated and submitted to CT (n = 20, 64.43 ± 3.13 years, 29.56 ± 4.80 kg/m²) and BWT (n = 20, 65.10 ± 4.86 years, 28.76 ± 4.26 kg/m²). We measured inflammation by the interleukin-6 (IL-6), interleukin-10 (IL-10), and tumor necrosis factor-α (TNF-α) assessments. For functional fitness, we used tests similar to activities of daily living. At the end of the 16 weeks, data from 24 women were analyzed, CT (n = 14) and BT (n = 10). Both groups reduced TNF-α and IL-6 levels, without differences in IL-10. Regarding functional fitness, both groups demonstrated improvements in all tests after 24 weeks, except for rise from prone position and the 400-meter walk test for CT. In summary, CT and BWT are effective in reducing the plasma concentration of pro-inflammatory cytokines and improving functional fitness in postmenopausal women.

Functional and traditional training improve muscle power and reduce proinflammatory cytokines in older women: A randomized controlled trial.

BACKGROUND: Aging is a natural process that, even in the nonattendance of complex diseases, is associated with a numerous behavioral change that attributes reduced muscle mass, power, strength and function. In addition, aging linked to low-grade inflammatory status, characterized by increased plasma concentrations of inflammatory cytokines such as TNF-α and IL-6. Physical exercise is the main non-pharmacological strategy for improving the physical fitness of the aged individuals. However, it is still controversial whether exercise can reduce aging-mediated inflammation. OBJECTIVE: To analyze the effects of functional (FT) and traditional (TT) training practice on muscle power and inflammatory profile in physically active older women. METHODS: The study has been performed for twenty-six weeks in which twenty-four weeks utilized for training sessions and two weeks for physical and biochemical assessments. Forty-three older women (age FT: 64.25 ± 4.70, range: 60-75; TT: 64.90 ± 3.03, range: 60-71; Control: 65.91 ± 5.79, range: 60-75) were randomly divided into three groups: Functional (FT; n = 16); Traditional (TT; n = 16) training groups; and Control Group (CG; n = 11) respectively. Muscle power tests were performed by push (Bench press) and squatting (Squat) actions. The jumping ability was performed through Counter Movement Jump (CMJ). In addition, isometric strength were assessed by Hand Grip Test. Plasma cytokine concentration was measured using flow cytometry. RESULTS: Functional and traditional training sessions subjected to aged women demonstrated a significant enhancement in their physical activity and muscle power. The trained individuals from above two groups showed significant improvements in all analyzed parameters excluding hand-grip. Functional and traditional training exercise reduced the plasma concentrations of TNF-α (FT: p = 0.0001; TT: p = 0.0410) and whereas FT group has reduced IL-6 (p = 0.0072), but did not affect the alterations of pre and post measurements of IL-2 (FT: p = 0.0651; TT: p = 0.2146) and IL-10 values (FT: p = 0.2658; TT: p = 0.3116). There was no significant difference in any of the test parameters between FT and TT groups. CONCLUSION: The functional and traditional training practices showed equivalent beneficial outcomes by increasing muscle power and reducing systemic markers associated with inflammation.

Influence of functional and traditional training on muscle power, quality of movement and quality of life in the elderly: a randomized and controlled clinical trial / Influência dos treinamentos funcional e tradicional na potência muscular, qualidade de movimento e qualidade de vida em idosas: um ensaio clínico randomizado e controlado

Abstract Aging causes a reduction in the adaptive capacity of the organism. Therefore, there is a decrease in physical fitness, making it difficult to perform basic movements and the development of muscular power. Thus, to minimize this reduction, functional and traditional training can both be used; however there is no clarity about which is most effective. The aim of this study was to identify the influence of functional and traditional training on muscle power, quality of movement and quality of life in the elderly. Fortyfour older women were randomly divided into functional group (FG n=18), traditional group (TG n=15) and control group (CG n=11). Thirty-six sessions lasting 50 minutes were performed. Quality of life (WHOQOL-bref ), quality of movement (FMS) and muscular power were evaluated. FG and TG increased significantly in relation to control group and to the initial FMS values. In FG and TG, muscle power significantly improved compared to pre-test, but not in relation to the control group. Regarding quality of life, only FG presented significant improvement. Both applied methods demonstrate the ability to improve the quality of movement and muscle power. However, functional training achieved better results in quality of life and movement.

Resumo O envelhecimento ocasiona uma redução na capacidade adaptativa do organismo. Por conseguinte, há uma diminuição na aptidão física dificultando a realização de movimentos básicos e o desenvolvimento de potência muscular. Desse modo, entre a formas de minimizar essa redução tanto treinamento funcional quanto o tradicional podem ser utilizado, contudo não há clareza sobre qual o mais eficaz. Objetivou-se identificar a influência dos treinamentos funcional e tradicional na potência muscular, qualidade de movimento e de vida em idosas. Quarenta e quatro idosas foram randomicamente divididas em grupo funcional (GF n=18), tradicional (GT n=15) e controle (GC n=11). Foram realizadas 36 sessões com duração de 50 minutos. Foram avaliadas a qualidade de vida (WHOQOL-bref), qualidade de movimento (FMS) e potência muscular. O GF e GT aumentaram significativamente em relação ao grupo controle e aos valores iniciais no FMS. Na potência muscular os grupos GF e GT melhoraram significativamente comparado ao pré-teste, mas não em relação ao controle. Na qualidade de vida apenas o GF apresentou melhora significativa. Ambos os métodos aplicados demostram a capacidade de melhorar a qualidade de movimento e potência muscular. Contudo o treinamento funcional obteve resultados superiores na qualidade de vida e de movimento.