Detalhe da pesquisa
1.
Hepatocytes of Wistar and Sprague Dawley rats differ significantly in their central metabolism.
J Cell Biochem
; 119(1): 909-917, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28671274
2.
Proteomic Characterization of Primary Mouse Hepatocytes in Collagen Monolayer and Sandwich Culture.
J Cell Biochem
; 119(1): 447-454, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28594086
3.
Metabolic fate of desomorphine elucidated using rat urine, pooled human liver preparations, and human hepatocyte cultures as well as its detectability using standard urine screening approaches.
Anal Bioanal Chem
; 408(23): 6283-94, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-27372715
4.
A shift in paradigm towards human biology-based systems for cholestatic-liver diseases.
J Physiol
; 593(23): 5043-55, 2015 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26417843
5.
Long-term maintenance of HepaRG cells in serum-free conditions and application in a repeated dose study.
J Appl Toxicol
; 34(10): 1078-86, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24114766
6.
Metabolic profiling using HPLC allows classification of drugs according to their mechanisms of action in HL-1 cardiomyocytes.
Toxicol Appl Pharmacol
; 252(2): 183-91, 2011 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21320520
7.
Cardiotoxicity testing using pluripotent stem cell-derived human cardiomyocytes and state-of-the-art bioanalytics: a review.
J Appl Toxicol
; 31(3): 191-205, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21328588
8.
Toward preclinical predictive drug testing for metabolism and hepatotoxicity by using in vitro models derived from human embryonic stem cells and human cell lines - a report on the Vitrocellomics EU-project.
Altern Lab Anim
; 39(2): 147-71, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21639679
9.
Gene expression profile of CD14+ blood monocytes following lifestyle-induced weight loss in individuals with metabolic syndrome.
Sci Rep
; 10(1): 17855, 2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33082492
10.
Enhanced cellular uptake and cytotoxicity studies of organometallic bioconjugates of the NLS peptide in Hep G2 cells.
Chembiochem
; 10(3): 493-502, 2009 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-19115329
11.
Effects of drugs in subtoxic concentrations on the metabolic fluxes in human hepatoma cell line Hep G2.
Toxicol Appl Pharmacol
; 240(3): 327-36, 2009 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19607853
12.
An integrated approach to improved toxicity prediction for the safety assessment during preclinical drug development using Hep G2 cells.
Toxicol Appl Pharmacol
; 237(2): 221-31, 2009 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19332084
13.
The Gut Microbiota and Hematopoietic Stem Cell Transplantation: Challenges and Potentials.
J Innate Immun
; 11(5): 405-415, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30286447
14.
Increased Circulating VAP-1 Levels Are Associated with Liver Fibrosis in Chronic Hepatitis C Infection.
J Clin Med
; 8(1)2019 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30658395
15.
Synthesis and pharmacological activities of 7-azaindole derivatives.
Pak J Pharm Sci
; 21(1): 36-9, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18166517
16.
Accessing 3D microtissue metabolism: Lactate and oxygen monitoring in hepatocyte spheroids.
Biosens Bioelectron
; 87: 941-948, 2017 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27665516
17.
Towards a 21st-century roadmap for biomedical research and drug discovery: consensus report and recommendations.
Drug Discov Today
; 22(2): 327-339, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27989722
18.
In Silico Modeling for the Prediction of Dose and Pathway-Related Adverse Effects in Humans From In Vitro Repeated-Dose Studies.
Toxicol Sci
; 149(1): 55-66, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26420750
19.
Novel human hepatic organoid model enables testing of drug-induced liver fibrosis in vitro.
Biomaterials
; 78: 1-10, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26618472
20.
Antibacterial activity of 1-methyl-7-methoxy-beta-carboline and its phenacyl and coumarine analogues.
Pak J Pharm Sci
; 18(3): 39-41, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16380342