Detalhe da pesquisa
1.
Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d.
Cell
; 175(1): 212-223.e17, 2018 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30241607
2.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.
Cell
; 175(7): 1756-1768.e17, 2018 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30550785
3.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.
Cell
; 178(2): 507-508, 2019 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31299203
4.
Synthetic fluorescent MYC probe: Inhibitor binding site elucidation and development of a high-throughput screening assay.
Bioorg Med Chem
; 42: 116246, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34130216
5.
Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states.
J Biol Chem
; 294(3): 953-967, 2019 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30478170
6.
Comparative Analysis of Cleavage Specificities of Immobilized Porcine Pepsin and Nepenthesin II under Hydrogen/Deuterium Exchange Conditions.
Anal Chem
; 92(16): 11018-11028, 2020 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32658454
7.
Deconvoluting AMP-activated protein kinase (AMPK) adenine nucleotide binding and sensing.
J Biol Chem
; 292(30): 12653-12666, 2017 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28615457
8.
Directed evolution of an ultrastable carbonic anhydrase for highly efficient carbon capture from flue gas.
Proc Natl Acad Sci U S A
; 111(46): 16436-41, 2014 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25368146
9.
Two-Site Evaluation of the Repeatability and Precision of an Automated Dual-Column Hydrogen/Deuterium Exchange Mass Spectrometry Platform.
Anal Chem
; 88(12): 6607-14, 2016 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27224086
10.
Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179.
Sci Signal
; 16(795): eadd9539, 2023 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37490546
11.
Patient-derived Siglec-6-targeting antibodies engineered for T-cell recruitment have potential therapeutic utility in chronic lymphocytic leukemia.
J Immunother Cancer
; 10(11)2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36442911
12.
Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gß5 signaling complex.
Science
; 375(6576): 86-91, 2022 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34793198
13.
One-step construction of circularized nanodiscs using SpyCatcher-SpyTag.
Nat Commun
; 12(1): 5451, 2021 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34521837
14.
Structures of the human LONP1 protease reveal regulatory steps involved in protease activation.
Nat Commun
; 12(1): 3239, 2021 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34050165
15.
Conformational Changes of RORγ During Response Element Recognition and Coregulator Engagement.
J Mol Biol
; 433(22): 167258, 2021 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34547329
16.
Structure-Activity Relationship and Biological Investigation of SR18292 (16), a Suppressor of Glucagon-Induced Glucose Production.
J Med Chem
; 64(2): 980-990, 2021 01 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33434430
17.
Structure of an AMPK complex in an inactive, ATP-bound state.
Science
; 373(6553): 413-419, 2021 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34437114
18.
Unique Polypharmacology Nuclear Receptor Modulator Blocks Inflammatory Signaling Pathways.
ACS Chem Biol
; 14(5): 1051-1062, 2019 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30951276
19.
Definition of functionally and structurally distinct repressive states in the nuclear receptor PPARγ.
Nat Commun
; 10(1): 5825, 2019 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31862968
20.
HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists.
Elife
; 82019 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31172947