Detalhe da pesquisa
1.
Structural polymorphism of coiled-coils from the stalk domain of SARS-CoV-2 spike protein.
FASEB J
; 36(3): e22199, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35157347
2.
Regulation of Peptidase Activity beyond the Active Site in Human Health and Disease.
Int J Mol Sci
; 24(23)2023 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38069440
3.
Zinc pyrithione is a potent inhibitor of PLPro and cathepsin L enzymes with ex vivo inhibition of SARS-CoV-2 entry and replication.
J Enzyme Inhib Med Chem
; 37(1): 2158-2168, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-35943189
4.
Evolutionary Analysis of Dipeptidyl Peptidase I.
Int J Mol Sci
; 23(3)2022 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35163774
5.
Kinetic Characterization of Cerium and Gallium Ions as Inhibitors of Cysteine Cathepsins L, K, and S.
Int J Mol Sci
; 23(16)2022 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36012257
6.
Regioselective Synthesis of 5- and 3-Hydroxy-N-Aryl-1H-Pyrazole-4-Carboxylates and Their Evaluation as Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase.
Molecules
; 27(15)2022 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35897941
7.
Synthesis and kinetic characterization of hyperbolic inhibitors of human cathepsins K and S based on a succinimide scaffold.
Bioorg Chem
; 115: 105213, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34364050
8.
Interplay between tetrameric structure, enzymatic activity and allosteric regulation of human dipeptidyl-peptidase I.
Arch Biochem Biophys
; 675: 108121, 2019 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31574257
9.
The catalytic domain of cathepsin C (dipeptidyl-peptidase I) alone is a fully functional endoprotease.
Protein Expr Purif
; 157: 21-27, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30703555
10.
Synthesis and biological evaluation of 7-(aminoalkyl)pyrazolo[1,5-a]pyrimidine derivatives as cathepsin K inhibitors.
Bioorg Chem
; 84: 226-238, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30502634
11.
Tetrahydro-1H,5H-pyrazolo[1,2-a]pyrazole-1-carboxylates as inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase.
Bioorg Chem
; 89: 102982, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31132601
12.
Cathepsin K cleavage of SDF-1α inhibits its chemotactic activity towards glioblastoma stem-like cells.
Biochim Biophys Acta Mol Cell Res
; 1864(3): 594-603, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28040478
13.
The two cathepsin B-like proteases of Arabidopsis thaliana are closely related enzymes with discrete endopeptidase and carboxydipeptidase activities.
Biol Chem
; 399(10): 1223-1235, 2018 09 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29924726
14.
The papain-like cysteine proteinases NbCysP6 and NbCysP7 are highly processive enzymes with substrate specificities complementary to Nicotiana benthamiana cathepsin B.
Biochim Biophys Acta Proteins Proteom
; 1865(4): 444-452, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28188928
15.
Synthesis of Novel 5-(N-Boc-N-Benzyl-2-aminoethyl)-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidin-3-carboxamides and Their Inhibition of Cathepsins B and K.
Acta Chim Slov
; 64(4): 782-789, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29318303
16.
Orthocaspases are proteolytically active prokaryotic caspase homologues: the case of Microcystis aeruginosa.
Mol Microbiol
; 98(1): 142-50, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26114948
17.
The death enzyme CP14 is a unique papain-like cysteine proteinase with a pronounced S2 subsite selectivity.
Arch Biochem Biophys
; 603: 110-7, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27246477
18.
Reactions of Medicinal Gold Compounds with Cathepsin B Explored through Electrospray Mass Spectrometry Measurements.
Chempluschem
; 89(2): e202300321, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37930642
19.
Cathepsin K: a unique collagenolytic cysteine peptidase.
Biol Chem
; 394(9): 1163-79, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23629523
20.
A novel photoaffinity-based probe for selective detection of cathepsin L active form.
Chembiochem
; 13(17): 2616-21, 2012 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23125066