Detalhe da pesquisa
1.
Comprehensive Analysis of R-Spondin Fusions and RNF43 Mutations Implicate Novel Therapeutic Options in Colorectal Cancer.
Clin Cancer Res
; 28(9): 1863-1870, 2022 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35254413
2.
Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy.
Cell Rep
; 35(5): 109071, 2021 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33951424
3.
First-in-Human, Healthy Volunteers Integrated Protocol of ETC-206, an Oral Mnk 1/2 Kinase Inhibitor Oncology Drug.
Clin Transl Sci
; 13(1): 57-66, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31343094
4.
The LIM/homeodomain protein Islet1 recruits Janus tyrosine kinases and signal transducer and activator of transcription 3 and stimulates their activities.
Mol Biol Cell
; 16(4): 1569-83, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15659653
5.
Induction of Human T-cell and Cytokine Responses Following Vaccination with a Novel Influenza Vaccine.
Sci Rep
; 8(1): 18007, 2018 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30573748
6.
Safety and immunogenicity of a virus-like particle pandemic influenza A (H1N1) 2009 vaccine: results from a double-blinded, randomized Phase I clinical trial in healthy Asian volunteers.
Vaccine
; 32(39): 5041-8, 2014 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25045806
7.
VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
Mol Cancer Ther
; 12(2): 151-61, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23270925
8.
Pharmacodynamic evaluation of the target efficacy of SB939, an oral HDAC inhibitor with selectivity for tumor tissue.
Mol Cancer Ther
; 10(7): 1207-17, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21586629
9.
SB939, a novel potent and orally active histone deacetylase inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer.
Mol Cancer Ther
; 9(3): 642-52, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20197387
10.
Modulation of the interleukin-6 receptor subunit glycoprotein 130 complex and its signaling by LMO4 interaction.
J Biol Chem
; 280(13): 12747-57, 2005 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15677447
11.
Protein kinase C delta associates with the interleukin-6 receptor subunit glycoprotein (gp) 130 via Stat3 and enhances Stat3-gp130 interaction.
J Biol Chem
; 277(51): 49134-42, 2002 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-12361954
12.
A novel sequence in the coiled-coil domain of Stat3 essential for its nuclear translocation.
J Biol Chem
; 278(31): 29252-60, 2003 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12746441
13.
GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction.
EMBO J
; 22(6): 1325-35, 2003 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-12628925