Detalhe da pesquisa
1.
Design and synthesis of 4-acetoxypentanamide derivatives of spliceostatin A and their biological evaluation towards prostate cancer treatment.
Bioorg Med Chem Lett
; 91: 129333, 2023 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37207846
2.
Microtubule inhibitors identified through nonbiased screening enhance DNA transfection efficiency by delaying p62-dependent ubiquitin recruitment.
Genes Cells
; 26(9): 739-751, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34212463
3.
Discovery of peroxisome proliferator-activated receptor α (PPARα) activators with a ligand-screening system using a human PPARα-expressing cell line.
J Biol Chem
; 293(26): 10333-10343, 2018 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29764933
4.
Structural development of 1H-pyrazolo-[3,4-b]pyridine-4-carboxylic acid derivatives as human peroxisome proliferator-activated receptor alpha (PPARα)-selective agonists.
Bioorg Med Chem Lett
; 29(16): 2124-2128, 2019 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31320147
5.
Unbiased compound screening with a reporter gene assay highlights the role of p13 in the cardiac cellular stress response.
Biochem Biophys Res Commun
; 495(2): 1992-1997, 2018 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29180011
6.
Semisynthesis and biological evaluation of a cotylenin A mimic derived from fusicoccin A.
Bioorg Med Chem Lett
; 28(4): 646-650, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29398541
7.
Bayesian approach enabled objective comparison of multiple human iPSC-derived Cardiomyocytes' Proarrhythmia sensitivities.
J Pharmacol Toxicol Methods
; : 107531, 2024 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38852688
8.
Celastrol suppresses humoral immune responses and autoimmunity by targeting the COMMD3/8 complex.
Sci Immunol
; 8(81): eadc9324, 2023 03 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37000855
9.
The K-Ras(G12D)-inhibitory peptide KS-58 suppresses growth of murine CT26 colorectal cancer cell-derived tumors.
Sci Rep
; 12(1): 8121, 2022 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35581303
10.
Gosha-jinki-Gan (GJG) shows anti-aging effects through suppression of TNF-α production by Chikusetsusaponin V.
Gene
; 815: 146178, 2022 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34995733
11.
Physicochemical and Biochemical Evaluation of Amorphous Solid Dispersion of Naringenin Prepared Using Hot-Melt Extrusion.
Front Nutr
; 9: 850103, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35571922
12.
Design and synthesis of pyrido[2,3-d]pyrimidine derivatives for a novel PAC1 receptor antagonist.
Eur J Med Chem
; 231: 114160, 2022 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35124531
13.
Discovery of Benzylpiperazine Derivatives as CNS-Penetrant and Selective Histone Deacetylase 6 Inhibitors.
ACS Med Chem Lett
; 13(7): 1077-1082, 2022 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35859864
14.
Design, Synthesis, and Monoamine Oxidase B Selective Inhibitory Activity of N-Arylated Heliamine Analogues.
ACS Med Chem Lett
; 13(10): 1582-1590, 2022 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36262392
15.
A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke.
Nat Commun
; 12(1): 4293, 2021 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34257294
16.
MARCKS-like protein, a membrane protein identified for its expression in developing neural retina, plays a role in regulating retinal cell proliferation.
Biochem J
; 408(1): 51-9, 2007 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17688421
17.
Opposing roles for SNAP23 in secretion in exocrine and endocrine pancreatic cells.
J Cell Biol
; 215(1): 121-138, 2016 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27697926
18.
Large-scale identification of proteins expressed in mouse embryonic stem cells.
Proteomics
; 5(5): 1346-61, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15742316
19.
Cell surface labeling and mass spectrometry reveal diversity of cell surface markers and signaling molecules expressed in undifferentiated mouse embryonic stem cells.
Mol Cell Proteomics
; 4(12): 1968-76, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16176923
20.
In vivo cross-linking of nucleosomal histones catalyzed by nuclear transglutaminase in starfish sperm and its induction by egg jelly triggering the acrosome reaction.
Eur J Biochem
; 270(18): 3750-9, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12950258