Ovarian hilus cell heterotopia.

A systematic pathologic study was done of the paratubal and parametrial tissues, submitted along with distal tubal segments excised for sterilization and with uteri (with or without attached adnexa) removed for common gynecologic conditions. Heterotopic ovarian hilus cell rests were noted in 12 cases, giving an overall incidence of 0.52% (12/2299). These cell rests, confined exclusively to the endosalpinx and perisalpinx, were easily differentiated from pregnancy-related decidual nodules, Walthard rests, foci of paratubal endometriosis, and ectopic adrenal rests.

Hypernephroma with perirenal hemorrhage.

Two cases of hypernephroma with rupture of the renal capsule and localized perirenal hemorrhage are reported. This unusual complication of hypernephroma exhibited a subacute clinical presentation with pain as the major presenting symptom.

Failed tubal sterilization as an etiologic factor in ectopic tubal pregnancy.

An indirect statistical method was used to demonstrate that failed tubal sterilization must be considered as a significant etiologic factor in tubal ectopic pregnancy. Since the exact incidence of poststerilization pregnancies was unknown in our population, a "theoretical" incidence of a 0.71% failure rate was used as the most realistic estimate on the basis of published reports of failed tubal sterilizations. From this figure the "expected" number of poststerilization conceptions, both total and tubal, was computed. The observed incidence of poststerilization ectopic tubal pregnancy was found to be 20 times the "expected" incidence in our population.

Incidental pregnancy luteoma associated with ectopic tubo-ovarian pregnancy: evidence in favor of origin from theca interna of an atretic follicle.

An incidental pregnancy luteoma was identified microscopically in an ovary submitted for ruptured ectopic tubo-ovarian pregnancy. The lesion consisted of a localized, non-encapsulated proliferation of thecal cells in the wall of an atretic follicle and had all the pathologic features of the typical late pregnancy luteoma. This finding is presented to support the origin of the pregnancy luteoma from the theca interna of atretic follicles.

Benign enlargement of the labia minora: report of two cases.

2 cases of bilateral hypertrophy of the labia minora are recorded. The patients presented with vulvar discomfort and redundant labia and reduction vulvoplasty was carried out. The resected specimens showed marked hyperplasia of the non-hair-bearing sebaceous glands, acanthosis, keratosis, and hyperpigmentation of the epithelium and a variable degree of neoangiogenesis and fibrosis in the upper dermis. No cause was established clinically or pathologically. The etiology and pathogenesis of this condition are briefly discussed.

Symptomatic plexiform tumor of the myometrium: report of a case.

The largest benign plexiform tumor of the myometrium on record is presented. The lesion, measuring 7.2 cm in diameter, was clinically palpable and symptomatic. The presence of scattered microfoci of typical smooth muscle differentiation within the tumor supports its smooth muscle origin.

Subcapsular adipocytic infiltration of the human ovary: a clinicopathologic study of eight cases.

A systematic pathologic study of excised ovaries uncovered 8 cases of microscopic adipocytic infiltration of the subcapsular ovarian cortical stroma among 449 patients subjected to unilateral or bilateral oophorectomy with or without hysterectomy for common gynecologic disorders. As this process was only detected in the routine paraffin sections, no fresh tissue was available for ultrastructural, histochemical and biochemical investigations. Its differential diagnosis is presented, and the possible role of obesity is discussed in its causation.

Adenomatoid tumor of the fimbrial endosalpinx: report of two cases with discussion of histogenesis.

Two asymptomatic cases of adenomatoid tumor, confined to the lamina propria of the tubal fimbria, are presented, and their location within strictly Müllerian territory is offered as indirect evidence for the Müllerian origin of this lesion. To stress the individuality of this distinct entity, the name of Müllerian mesothelioma is suggested.

Combined adrenorenal fusion and adrenohepatic adhesion: a case report with review of the literature and discussion of pathogenesis.

The second case of combined adrenorenal fusion and adrenohepatic adhesion on the right side is reported. It is hypothesized that the basic lesion underlying this innocuous anomaly rests in the periadrenal mesenchyme. In the case of fusion of adrenal with kidney or liver the mesenchymal defect causes 1) retardation of capsule formation with parenchymal mixing and 2) failure of local differentiation into fetal and later adult fat cells. In the case of adhesion of adrenal to kidney or liver there is no retardation of capsule formation with parenchymal mixing but only failure to differentiate locally into fat cells. Consequently, there is no physical separation of these organs by interposition of fat cells and there is variable party-wall sharing of the capsule.

Serous papillary neoplasms arising in paramesonephric parovarian cysts. A report of eight cases.

Eight cases of papillary serous cystadenoma arising in paramesonephric parovarian cysts are presented. None of these benign lesions were diagnosed preoperatively as such and were only detected pathologically. In only one case was the tumor-bearing cyst symptomatic owing to its large size. The etiology, pathogenesis, and evolution of this lesion are briefly discussed.

Asymptomatic bilateral hypernephroma: an autopsy case report wtih discussion of possible etiologic factors.

The first case of asymptomatic bilateral synchronous hypernephroma is described in a 52-year-old man who had a long history of alcoholic cirrhosis and died of uncontrollable gastrointestinal bleeding. The literature is reviewed briefly and relevant etiologic factors are discussed.

Gastritic glandularis et cystica profunda: a report of three cases with discussion of etiology and pathogenesis.

Three cases of gastritis glandularis et cystica profunda are presented, two associated with severe chronic gastritis and the other with invasive gastric carcinoma and chronic gastritis. This poorly known entity consists of benign downgrowths of deep gastric glands through the muscularis mucosae into the submucosa. The pattern is primarily adenomatous with secondary cyst formation, which varies in extent and severity. The lesion is related to the chronic gastritis but why it should occur so rarely in such a common condition as chronic gastritis remains obscure. More documented cases are needed before a meaningful analysis can be attempted.