Detalhe da pesquisa
1.
Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation.
J Neurosci
; 33(22): 9498-507, 2013 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23719816
2.
Imbalance of Hsp70 family variants fosters tau accumulation.
FASEB J
; 27(4): 1450-9, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23271055
3.
Cdc37/Hsp90 protein complex disruption triggers an autophagic clearance cascade for TDP-43 protein.
J Biol Chem
; 287(29): 24814-20, 2012 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22674575
4.
Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism.
J Biol Chem
; 287(48): 40661-9, 2012 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23035116
5.
The Hsp90 kinase co-chaperone Cdc37 regulates tau stability and phosphorylation dynamics.
J Biol Chem
; 286(19): 16976-83, 2011 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21367866
6.
The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules.
J Neurosci
; 30(2): 591-9, 2010 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20071522
7.
Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice.
J Neurosci
; 30(46): 15374-82, 2010 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-21084594
8.
Hsc70 rapidly engages tau after microtubule destabilization.
J Biol Chem
; 285(22): 16798-805, 2010 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20308058
9.
The diarylheptanoid (+)-aR,11S-myricanol and two flavones from bayberry (Myrica cerifera) destabilize the microtubule-associated protein tau.
J Nat Prod
; 74(1): 38-44, 2011 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21141876
10.
Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency.
PLoS One
; 9(9): e107241, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25191701
11.
The role of FKBP5 in mood disorders: action of FKBP5 on steroid hormone receptors leads to questions about its evolutionary importance.
CNS Neurol Disord Drug Targets
; 12(8): 1157-62, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24040820
12.
Accelerated neurodegeneration through chaperone-mediated oligomerization of tau.
J Clin Invest
; 123(10): 4158-69, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23999428
13.
Rhodacyanine derivative selectively targets cancer cells and overcomes tamoxifen resistance.
PLoS One
; 7(4): e35566, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22563386
14.
Neuronal life span versus health span: principles of natural selection at work in the degenerating brain.
J Mol Neurosci
; 45(3): 467-72, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21559875
15.
A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51.
PLoS One
; 6(9): e24840, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21935478
16.
Hsp70 ATPase Modulators as Therapeutics for Alzheimer's and other Neurodegenerative Diseases.
Mol Cell Pharmacol
; 2(2): 43-46, 2010 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20523917
17.
Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden.
Mol Neurodegener
; 5: 45, 2010 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21040568