Detalhe da pesquisa
1.
An enzymatic Alder-ene reaction.
Nature
; 586(7827): 64-69, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32999480
2.
Discovery and Characterization of Pyridoxal 5'-Phosphate-Dependent Cycloleucine Synthases.
J Am Chem Soc
; 146(21): 14672-14684, 2024 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38743881
3.
Biosynthesis of AS2077715 and Funiculosin: Pathway Reconstitution and Identification of Enzymes that Form the All-cis Cyclopentanetetraol Moiety.
J Am Chem Soc
; 145(12): 6643-6647, 2023 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36920241
4.
Enzymatic cis-Decalin Formation in Natural Product Biosynthesis.
J Am Chem Soc
; 145(6): 3301-3305, 2023 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36723171
5.
Biosynthesis of Polycyclic Natural Products from Conjugated Polyenes via Tandem Isomerization and Pericyclic Reactions.
J Am Chem Soc
; 145(25): 13520-13525, 2023 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37310230
6.
Deciphering chemical logic of fungal natural product biosynthesis through heterologous expression and genome mining.
Nat Prod Rep
; 40(1): 89-127, 2023 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36125308
7.
Prospecting for natural products by genome mining and microcrystal electron diffraction.
Nat Chem Biol
; 17(8): 872-877, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34312563
8.
SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis.
Nature
; 549(7673): 502-506, 2017 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28902839
9.
Enzymatic Benzofuranoindoline Formation in the Biosynthesis of the Strained Bridgehead Bicyclic Dipeptide (+)-Azonazine A.
Angew Chem Int Ed Engl
; 62(40): e202311266, 2023 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37589717
10.
Computational Prediction and Experimental Validation of a Bridged Cation Intermediate in Akanthomycin Biosynthesis.
J Am Chem Soc
; 144(12): 5280-5283, 2022 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35297629
11.
Biosynthesis of Terpenoid-Pyrrolobenzoxazine Hybrid Natural Product CJ-12662.
Angew Chem Int Ed Engl
; 61(12): e202116928, 2022 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35075754
12.
AoiQ Catalyzes Geminal Dichlorination of 1,3-Diketone Natural Products.
J Am Chem Soc
; 143(19): 7267-7271, 2021 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33957045
13.
Biosynthesis of para-Cyclophane-Containing Hirsutellone Family of Fungal Natural Products.
J Am Chem Soc
; 143(15): 5605-5609, 2021 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33834778
14.
Iterative Catalysis in the Biosynthesis of Mitochondrial Complex II Inhibitors Harzianopyridone and Atpenin B.
J Am Chem Soc
; 142(19): 8550-8554, 2020 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32365298
15.
Genome Mining of Alkaloidal Terpenoids from a Hybrid Terpene and Nonribosomal Peptide Biosynthetic Pathway.
J Am Chem Soc
; 142(2): 710-714, 2020 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31885262
16.
Genome-Mined Diels-Alderase Catalyzes Formation of the cis-Octahydrodecalins of Varicidin A and B.
J Am Chem Soc
; 141(2): 769-773, 2019 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30609896
17.
Enzyme-Catalyzed Inverse-Electron Demand Diels-Alder Reaction in the Biosynthesis of Antifungal Ilicicolin H.
J Am Chem Soc
; 141(14): 5659-5663, 2019 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30905148
18.
Enzymatic Intermolecular Hetero-Diels-Alder Reaction in the Biosynthesis of Tropolonic Sesquiterpenes.
J Am Chem Soc
; 141(36): 14052-14056, 2019 09 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31461283
19.
The expanding world of biosynthetic pericyclases: cooperation of experiment and theory for discovery.
Nat Prod Rep
; 36(5): 698-713, 2019 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30311924
20.
Different structures of the two peroxisome proliferator-activated receptor gamma (PPARγ) ligand-binding domains in homodimeric complex with partial agonist, but not full agonist.
Bioorg Med Chem Lett
; 25(13): 2639-44, 2015 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25987371