Clinical evaluation of the effects of ketamine sedation on pediatric dental patients.

This study was undertaken to determine the dosages, treatment times and side effects of ketamine HCI with and without two benzodiazepines when used for sedation on a group of precooperative children at the UCLA Children's Dental Center. Ketamine was evaluated when used alone, and in conjunction with two benzodiazepines, diazepam or a new water-soluble midazolam. An anti-muscarinic, atropine or glycopyrrolate, and nitrous oxide-oxygen were included in all sedations. Mean treatment times were increased significantly when ketamine and a benzodiazepine were used in combination. Additionally, mean ketamine dosages were decreased significantly when ketamine was utilized in combination with a benzodiazepine. All children tolerated the sedation well and there were no severe adverse reactions. Side effects included nausea, vomiting, and a rise in post-operative temperatures.

Bleeding control after extractions in a patient with aplastic anemia during bone marrow transplantation: report of case.

This report describes a method of bleeding control at dental extraction sites using medicaments (thrombin, cocaine, Amicar, Surgicel) in conjunction with a dental appliance containing vinyl polysiloxane silicone putty (Optosil) to provide greater coverage and pressure at the extraction sites. The acrylic splint was used to control bleeding in a 15-year-old male, with an aplastic pancytopenia anemia, who had required removal of severely mobile exfoliating teeth prior to a bone marrow transplantation procedure.