Detalhe da pesquisa
1.
Landscape and function of multiple mutations within individual oncogenes.
Nature
; 582(7810): 95-99, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32494066
2.
Binding Mechanism between Platelet Glycoprotein and Cyclic Peptide Elucidated by McMD-Based Dynamic Docking.
J Chem Inf Model
; 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38751042
3.
Network-based prediction approach for cancer-specific driver missense mutations using a graph neural network.
BMC Bioinformatics
; 24(1): 383, 2023 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37817080
4.
Inhibition of the bone morphogenetic protein pathway suppresses tumor growth through downregulation of epidermal growth factor receptor in MEK/ERK-dependent colorectal cancer.
Cancer Sci
; 114(9): 3636-3648, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37357017
5.
Deep Learning-Based Differential Diagnosis of Follicular Thyroid Tumors Using Histopathological Images.
Mod Pathol
; 36(11): 100296, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37532181
6.
CBNplot: Bayesian network plots for enrichment analysis.
Bioinformatics
; 38(10): 2959-2960, 2022 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35561164
7.
Improving Compound-Protein Interaction Prediction by Self-Training with Augmenting Negative Samples.
J Chem Inf Model
; 63(15): 4552-4559, 2023 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37460105
8.
VGAE-MCTS: A New Molecular Generative Model Combining the Variational Graph Auto-Encoder and Monte Carlo Tree Search.
J Chem Inf Model
; 63(23): 7392-7400, 2023 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37993764
9.
Individual health-disease phase diagrams for disease prevention based on machine learning.
J Biomed Inform
; 144: 104448, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37467834
10.
eSkip-Finder: a machine learning-based web application and database to identify the optimal sequences of antisense oligonucleotides for exon skipping.
Nucleic Acids Res
; 49(W1): W193-W198, 2021 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34104972
11.
Development and validation of ischemic heart disease and stroke prognostic models using large-scale real-world data from Japan.
Environ Health Prev Med
; 28: 16, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36792224
12.
Protein-ligand binding affinity prediction of cyclin-dependent kinase-2 inhibitors by dynamically averaged fragment molecular orbital-based interaction energy.
J Comput Chem
; 43(20): 1362-1371, 2022 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35678372
13.
AI-Driven Synthetic Route Design Incorporated with Retrosynthesis Knowledge.
J Chem Inf Model
; 62(6): 1357-1367, 2022 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35258953
14.
Single-Image Super-Resolution Improvement of X-ray Single-Particle Diffraction Images Using a Convolutional Neural Network.
J Chem Inf Model
; 62(14): 3352-3364, 2022 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35820663
15.
Repertoires of G protein-coupled receptors for Ciona-specific neuropeptides.
Proc Natl Acad Sci U S A
; 116(16): 7847-7856, 2019 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30936317
16.
Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations.
Proc Natl Acad Sci U S A
; 116(20): 10025-10030, 2019 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31043566
17.
Oncogenic mutations Q61L and Q61H confer active form-like structural features to the inactive state (state 1) conformation of H-Ras protein.
Biochem Biophys Res Commun
; 565: 85-90, 2021 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34102474
18.
Trp53 Mutation in Keratin 5 (Krt5)-Expressing Basal Cells Facilitates the Development of Basal Squamous-Like Invasive Bladder Cancer in the Chemical Carcinogenesis of Mouse Bladder.
Am J Pathol
; 190(8): 1752-1762, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32339497
19.
Metagenomic profiling of gut microbiome in early chronic kidney disease.
Nephrol Dial Transplant
; 36(9): 1675-1684, 2021 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32869063
20.
Discovery of natural TRPA1 activators through pharmacophore-based virtual screening and a biological assay.
Bioorg Med Chem Lett
; 31: 127639, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33129991