Detalhe da pesquisa
1.
MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis.
Mol Cell
; 74(3): 571-583.e8, 2019 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30898438
2.
Design and synthesis of quinazolin-4-one derivatives as potential anticancer agents and investigation of their interaction with RecQ helicases.
Bioorg Chem
; 144: 107086, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38219478
3.
Structure of the human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp bound to a dsDNA-ssDNA junction.
Nucleic Acids Res
; 50(14): 8279-8289, 2022 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35819203
4.
Cryo-EM structure of the Smc5/6 holo-complex.
Nucleic Acids Res
; 50(16): 9505-9520, 2022 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35993814
5.
Nse5/6 is a negative regulator of the ATPase activity of the Smc5/6 complex.
Nucleic Acids Res
; 49(8): 4534-4549, 2021 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33849072
6.
Phosphorylation-dependent assembly and coordination of the DNA damage checkpoint apparatus by Rad4(TopBP1).
Mol Cell
; 51(6): 723-736, 2013 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-24074952
7.
Are SMC Complexes Loop Extruding Factors? Linking Theory With Fact.
Bioessays
; 41(1): e1800182, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30506702
8.
The structural basis for substrate recognition by mammalian polynucleotide kinase 3' phosphatase.
Mol Cell
; 44(3): 385-96, 2011 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22055185
9.
DIS3 isoforms vary in their endoribonuclease activity and are differentially expressed within haematological cancers.
Biochem J
; 475(12): 2091-2105, 2018 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29802118
10.
A Hypomorphic PALB2 Allele Gives Rise to an Unusual Form of FA-N Associated with Lymphoid Tumour Development.
PLoS Genet
; 12(3): e1005945, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26990772
11.
Chromatin association of the SMC5/6 complex is dependent on binding of its NSE3 subunit to DNA.
Nucleic Acids Res
; 44(3): 1064-79, 2016 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26446992
12.
Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2.
Biochem J
; 473(13): 1869-79, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27099339
13.
The XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 function.
Nucleic Acids Res
; 43(14): 6934-44, 2015 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26130715
14.
PP2A/B55 and Fcp1 regulate Greatwall and Ensa dephosphorylation during mitotic exit.
PLoS Genet
; 10(1): e1004004, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24391510
15.
The BAH domain of Rsc2 is a histone H3 binding domain.
Nucleic Acids Res
; 41(19): 9168-82, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23907388
16.
Development of an oligonucleotide-based fluorescence assay for the identification of tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors.
Anal Biochem
; 454: 17-22, 2014 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24637157
17.
Structural basis for recruitment of BRCA2 by PALB2.
EMBO Rep
; 18(7): 1264, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28673926
18.
TopBP1 utilises a bipartite GINS binding mode to support genome replication.
Nat Commun
; 15(1): 1797, 2024 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38413589
19.
Structure and function of the Rad9-binding region of the DNA-damage checkpoint adaptor TopBP1.
Nucleic Acids Res
; 39(1): 313-24, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20724438
20.
Schizosaccharomyces pombe Rtf2 is important for replication fork barrier activity of RTS1 via splicing of Rtf1.
Elife
; 122023 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37615341