Detalhe da pesquisa
1.
Human-specific duplicate CHRFAM7A gene is associated with more severe osteoarthritis and amplifies pain behaviours.
Ann Rheum Dis
; 82(5): 710-718, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36627169
2.
Senescent cell population with ZEB1 transcription factor as its main regulator promotes osteoarthritis in cartilage and meniscus.
Ann Rheum Dis
; 82(3): 403-415, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36564153
3.
Targeting FoxO transcription factors with HDAC inhibitors for the treatment of osteoarthritis.
Ann Rheum Dis
; 82(2): 262-271, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36109140
4.
FOXO1 and FOXO3 transcription factors have unique functions in meniscus development and homeostasis during aging and osteoarthritis.
Proc Natl Acad Sci U S A
; 117(6): 3135-3143, 2020 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31980519
5.
Krüppel-like factor-4 and Krüppel-like factor-2 are important regulators of joint tissue cells and protect against tissue destruction and inflammation in osteoarthritis.
Ann Rheum Dis
; 2022 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35534137
6.
Increased autophagy in CD4+ T cells of rheumatoid arthritis patients results in T-cell hyperactivation and apoptosis resistance.
Eur J Immunol
; 46(12): 2862-2870, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27624289
7.
Vascular remodeling underlies rebleeding in hemophilic arthropathy.
Am J Hematol
; 90(11): 1027-35, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26257191
8.
vSPACE: Exploring Virtual Spatial Representation of Articular Chondrocytes at the Single-Cell Level.
bioRxiv
; 2024 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38370845
9.
Shared and Compartment-Specific Processes in Nucleus Pulposus and Annulus Fibrosus During Intervertebral Disc Degeneration.
Adv Sci (Weinh)
; 11(17): e2309032, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38403470
10.
RNA-binding proteins that are highly expressed and enriched in healthy cartilage but suppressed in osteoarthritis.
Front Cell Dev Biol
; 11: 1208315, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37457300
11.
Mocetinostat activates Krüppel-like factor 4 and protects against tissue destruction and inflammation in osteoarthritis.
JCI Insight
; 8(17)2023 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37681413
12.
Suppression of Autoimmune Rheumatoid Arthritis with Hybrid Nanoparticles That Induce B and T Cell Tolerance to Self-Antigen.
ACS Nano
; 16(12): 20206-20221, 2022 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36418226
13.
Urolithin A improves mitochondrial health, reduces cartilage degeneration, and alleviates pain in osteoarthritis.
Aging Cell
; 21(8): e13662, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35778837
14.
The mechanosensitive ion channel PIEZO1 is expressed in tendons and regulates physical performance.
Sci Transl Med
; 14(647): eabj5557, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35648809
15.
Mohawk is a transcription factor that promotes meniscus cell phenotype and tissue repair and reduces osteoarthritis severity.
Sci Transl Med
; 12(567)2020 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33115953
16.
TAFI deficiency causes maladaptive vascular remodeling after hemophilic joint bleeding.
JCI Insight
; 4(19)2019 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31465300
17.
Wwp2 maintains cartilage homeostasis through regulation of Adamts5.
Nat Commun
; 10(1): 2429, 2019 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31160553
18.
Platelet-derived growth factor-coated decellularized meniscus scaffold for integrative healing of meniscus tears.
Acta Biomater
; 76: 126-134, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29908335
19.
FoxO transcription factors modulate autophagy and proteoglycan 4 in cartilage homeostasis and osteoarthritis.
Sci Transl Med
; 10(428)2018 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29444976
20.
FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration.
Aging Cell
; 17(5): e12800, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29963746