Detalhe da pesquisa
1.
ApoE Isoforms Inhibit Amyloid Aggregation of Proinflammatory Protein S100A9.
Int J Mol Sci
; 25(4)2024 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38396791
2.
Plasma IAPP-Autoantibody Levels in Alzheimer's Disease Patients Are Affected by APOE4 Status.
Int J Mol Sci
; 24(4)2023 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36835187
3.
Tandem Ring Opening/Intramolecular [2 + 2] Cycloaddition Reaction for the Synthesis of Cyclobutane Fused Thiazolino-2-Pyridones.
J Org Chem
; 86(23): 16582-16592, 2021 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34767366
4.
K2S2O8-mediated coupling of 6-amino-7-aminomethyl-thiazolino-pyridones with aldehydes to construct amyloid affecting pyrimidine-fused thiazolino-2-pyridones.
Org Biomol Chem
; 19(44): 9758-9772, 2021 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34730163
5.
Intramolecular Povarov Reactions for the Synthesis of Chromenopyridine Fused 2-Pyridone Polyheterocycles Binding to α-Synuclein and Amyloid-ß Fibrils.
J Org Chem
; 85(21): 14174-14189, 2020 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33099999
6.
Morphological analysis of Apolipoprotein E binding to Aß Amyloid using a combination of Surface Plasmon Resonance, Immunogold Labeling and Scanning Electron Microscopy.
BMC Biotechnol
; 19(1): 97, 2019 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31829176
7.
Pyridine-Fused 2-Pyridones via Povarov and A3 Reactions: Rapid Generation of Highly Functionalized Tricyclic Heterocycles Capable of Amyloid Fibril Binding.
J Org Chem
; 84(7): 3887-3903, 2019 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30862161
8.
Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals.
Environ Sci Technol
; 52(20): 11865-11874, 2018 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30226982
9.
Structure-Based Virtual Screening Protocol for in Silico Identification of Potential Thyroid Disrupting Chemicals Targeting Transthyretin.
Environ Sci Technol
; 50(21): 11984-11993, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27668830
10.
The N-terminal region of amyloid ß controls the aggregation rate and fibril stability at low pH through a gain of function mechanism.
J Am Chem Soc
; 136(31): 10956-64, 2014 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25014209
11.
Transthyretin is dysregulated in preeclampsia, and its native form prevents the onset of disease in a preclinical mouse model.
Am J Pathol
; 183(5): 1425-1436, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24035612
12.
The role of pro-inflammatory S100A9 in Alzheimer's disease amyloid-neuroinflammatory cascade.
Acta Neuropathol
; 127(4): 507-22, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24240735
13.
Ca(2+) enhances Aß polymerization rate and fibrillar stability in a dynamic manner.
Biochem J
; 450(1): 189-97, 2013 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23171033
14.
Interactions between DNA, transcriptional regulator Dreb2a and the Med25 mediator subunit from Arabidopsis thaliana involve conformational changes.
Nucleic Acids Res
; 40(13): 5938-50, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22447446
15.
Structural topology and activation of an initial adenylate kinase-substrate complex.
Biochemistry
; 52(6): 1055-61, 2013 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23339454
16.
Modulation of α-synuclein fibrillization by ring-fused 2-pyridones: templation and inhibition involve oligomers with different structure.
Arch Biochem Biophys
; 532(2): 84-90, 2013 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23399432
17.
Mechanisms of protein oligomerization: inhibitor of functional amyloids templates α-synuclein fibrillation.
J Am Chem Soc
; 134(7): 3439-44, 2012 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22260746
18.
Characterization of SPINK9, a KLK5-specific inhibitor expressed in palmo-plantar epidermis.
Biol Chem
; 393(5): 369-77, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22505519
19.
The effect of capsular repair, bone block healing, and position on the results of the Bristow-Latarjet procedure (study III): long-term follow-up in 319 shoulders.
J Shoulder Elbow Surg
; 21(5): 647-60, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21719316
20.
Endogenous Human Proteins Interfering with Amyloid Formation.
Biomolecules
; 12(3)2022 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35327638