Improving livelihoods in East Africa through livestock research and extension: reflections on changes from the 1950s to the early twenty first century.

This paper discusses the major changes in development thinking that, in our view, have characterized livestock research and extension in Africa since the 1950s. It describes the institutional and ideological environment in which research and extension was then conducted and provides examples of early successes aimed at enhancing productivity. There was then a gradual broadening of the scope of research and extension to internalize the wider contexts of the challenges of improving livelihoods. The four main over-arching changes discussed are: poverty-focus, gender-sensitivity, participation and holism. The discussion ends by speculating on directions for the future.

Risk assessment for Escherichia coli O157:H7 in marketed unpasteurized milk in selected East African countries.

We carried out a study to assess the risk associated with the presence of Shiga toxigenic Escherichia coli (STEC) in informally marketed unpasteurized milk in urban East Africa. Data for the risk models were obtained from on-going and recently completed studies in Kenya and Uganda. Inputs for the model were complemented with data from published literature in similar populations. A fault-tree scenario pathway and modular process risk model approach were used for exposure assessment. Hazard characterization was based on a socioeconomic study with dose-responses derived from the literature. We used a probabilistic approach with Monte Carlo simulation and inputs from farm and household surveys. The qualitative analysis suggested a low to moderate risk of infection from consuming milk and that the widespread consumer practice of boiling milk before consumption was an important risk mitigator. Quantitative analysis revealed that two to three symptomatic STEC infections could be expected for every 10,000 unpasteurized milk portions consumed, with a possible range of 0 to 22 symptomatic cases. Sensitivity analyses to assess the uncertainty and variability associated with the model revealed that the factor with the greatest influence on disease incidence was the prevalence of STEC in dairy cattle. Risk assessment is a potentially useful method for managing food safety in informal markets.

Feeding practices and effects of gastrointestinal parasite infections on live weight gain of small ruminants in smallholder mixed farms in Kenya.

The objective of this study was to quantify the effects of gastrointestinal nematodosis on live weight gain (LWG) of sheep and goats kept in smallholder farms in Kenya. A total of 307 sheep and goats from smallholder farms were sampled using a 2-stage cluster and systematic random approach. Sampled farms were visited once a month for nine months during which a health and production survey questionnaire was administered, animals weighed and fecal samples taken for fecal egg count. Descriptive statistics and a generalized linear mixed model were performed in SAS. The mean LWG of suckling kids and lambs was low (mean=46 g/day). High fecal egg count and lack of feed supplementation were identified as the main factors limiting growth. Improved helminth control and nutrition are required to optimize production.

Investigation of the risk of exposure to antimicrobial residues present in marketed milk in Tanzania.

Concerns about food safety are increasing in developing countries where urbanization and changing life styles are associated with greater dependence on marketed foods. Ensuring the safety of animal products supplied from smallholder and pastoral systems in these countries presents a great challenge. The risk of consumer exposure to marketed milk containing antimicrobial residues was investigated by testing 986 samples of unpasteurized milk collected in dry and wet seasons from market agents along milk supply chains in and around Mwanza and Dar es Salaam in Tanzania during 1999 and 2000 and estimating the frequency of consuming such milk. With the Charm-AIM screening test kit, antimicrobial residues were detected in 36% of marketed milk samples, suggesting an average risk of about 11 exposures per month for a daily consumer of milk. The higher prevalence levels of the residues were not significantly different by site or season, as had been hypothesized. Recommendations to address this problem are (i) creation of awareness among policy makers, who are currently unaware of the milk safety problem, and development of potential interventions to address the problem, (ii) testing for the residues at milk collection centers, and (iii) further investigation of milk production practices used by the predominantly smallholder producers and market agents. Risks should be characterized and estimated to provide a basis for designing appropriate extension messages and effective management strategies for protecting the health of consumers without unnecessarily jeopardizing the livelihood benefits derived from dairying by producers and market agents.

Risk of infection with Brucella abortus and Escherichia coli O157:H7 associated with marketing of unpasteurized milk in Kenya.

As part of a study to assess zoonotic milk-borne health risks, seasonal survey data and unpasteurized milk samples were collected between January 1999 and February 2000 from randomly selected informal milk market agents (220 and 236 samples in the dry and wet seasons, respectively) and from households purchasing raw milk (213 and 219 samples in the dry and wet seasons, respectively) in rural and urban locations in central Kenya and screened for antibodies to Brucella abortus (B. abortus) and presence of Escherichia coli (E. coli) O157:H7. The latter was assessed based on samples from consumer households only. Antibodies to B. abortus were screened using the indirect antibody Enzyme Linked Immunosorbent Assay (ELISA) and the Milk Ring Test (MRT). The presence of E. coli O157:H7 was assessed by culture, biochemical characterisation, serological testing for production of verocytotoxin one (VT1) and two (VT2) and polymerase chain reaction (PCR) analysis for the presence of genes encoding for the toxins. The prevalence of antibodies to B. abortus varied considerably ranging from none in milk sold in small units and originating from intensive production systems to over 10% in samples that were bulked or originating from extensive production systems. E. coli O157:H7 was isolated from two samples (0.8%), one of which produced VT1. All urban consumers (100%) and nearly all rural consumers (96%) of marketed milk boiled the milk before consumption, mainly in tea, thus greatly reducing chances of exposure to live pathogens and potential health risks.

Comparison of African swine fever virus prevalence and risk in two contrasting pig-farming systems in South-west and Central Kenya.

We describe a horizontal survey of African swine fever virus (ASFV) prevalence and risk factors associated with virus infection in domestic pigs in two contrasting production systems in Kenya. A free range/tethering, low input production system in Ndhiwa District of South-western Kenya is compared with a medium input stall fed production system in Kiambu District of Central Kenya. Analysis of variance (ANOVA) of data derived from cluster analysis showed that number of animals, number of breeding sows and number of weaner pigs were a significant factor in classifying farms in Nhiwa and Kiambu. Analysis of blood and serum samples using a PCR assay demonstrated an average animal level positivity to ASFV of 28% in two independent samplings in South-western Kenya and 0% PCR positivity in Central Kenya. No animals were sero-positive in either study site using the OIE indirect-ELISA and none of the animals sampled exhibited clinical symptoms of ASF. The farms that contained ASFV positive pigs in Ndhiwa District were located in divisions bordering the Ruma National Park from which bushpig (Potamochoerus larvatus) incursions into farms had been reported. ASFV prevalence (P<0.05) was significantly higher at distances between 6 and 16km from the National Park than at distances closer or further away. One of the 8 bushpigs sampled from the park, from which tissues were obtained was PCR positive for ASFV. The data therefore indicated a potential role for the bushpig in virus transmission in South-western Kenya, but there was no evidence of a direct sylvatic virus transmission cycle in Central Kenya. ASF control strategies implemented in these areas will need to take these epidemiological findings into consideration.

Invited review: Role of livestock in human nutrition and health for poverty reduction in developing countries.

Livestock keeping is critical for many of the poor in the developing world, often contributing to multiple livelihood objectives and offering pathways out of poverty. Livestock keeping also affects an indispensable asset of the poor, their human capital, through its impact on their own nutrition and health. This paper outlines the linkages between livestock keeping and the physical well-being of the poor, and examines a number of commonly held beliefs that misrepresent livestock development issues related to these linkages. These beliefs limit the scope of intervention programs to promote livestock and limit their potential contribution to poverty reduction. Recognition of the complexity of the role livestock play in household decision-making and of the opportunities foregone due to these misconceptions can enhance the ability of livestock to contribute to human well-being in the developing world.

Impact of mastitis control measures on milk production and mastitis indicators in smallholder dairy farms in Kiambu district, Kenya.

Bovine mastitis and mastitis control were investigated on smallholder farms in central Kenya. After an initial observational study, a clinical trial to assess the impact of three different mastitis control strategies--(1) improved udder hygiene, (2) treatment of subclinical cases, and (3) a combination of these--was conducted on 100 randomly selected farms with 332 lactating cows. Before the implementation of control measures, the milk yield was low (mean 6.5 kg/day; median 6 kg/day) and somatic cell counts (SCC) were high, with 80% and 43% of cows having milk with SCC greater than 250 x 10(3) cells/ml and 600 x 10(3) cells/ml, respectively. Infectious pathogens were also commonly isolated, with 63% of cows being positive for pathogenic bacteria. Neither intervention strategy alone had any effect on mastitis indicators or milk yield. In combination, the measures had some impact, lowering the prevalence of contagious pathogens by 18%, but this was not reflected in a significantly increased milk yield, lowered SCC or reduced incidence of clinical mastitis.