Detalhe da pesquisa
1.
Arriba por la Vida Estudio: a randomized controlled trial promoting standing behavior to reduce sitting time among postmenopausal Latinas.
J Behav Med
; 2024 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38722441
2.
Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein.
Hum Mol Genet
; 28(1): 31-50, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30219847
3.
E46K-like α-synuclein mutants increase lipid interactions and disrupt membrane selectivity.
J Biol Chem
; 294(25): 9799-9812, 2019 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31048377
4.
The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease.
PLoS Biol
; 15(3): e2000374, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28257421
5.
Correction: The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease.
PLoS Biol
; 15(4): e1002601, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28379951
6.
Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity.
Proc Natl Acad Sci U S A
; 113(42): E6506-E6515, 2016 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27708160
7.
Small-Molecule-Induced Soluble Oligomers of α-Synuclein with Helical Structure.
Chemistry
; 23(53): 13010-13014, 2017 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28763125
8.
S100A4 protects the myocardium against ischemic stress.
J Mol Cell Cardiol
; 100: 54-63, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27721024
9.
Pathological hypertrophy amelioration by PRAS40-mediated inhibition of mTORC1.
Proc Natl Acad Sci U S A
; 110(31): 12661-6, 2013 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23842089
10.
Burial of the polymorphic residue 129 in amyloid fibrils of prion stop mutants.
J Biol Chem
; 288(5): 2994-3002, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23209282
11.
Mechanistic target of rapamycin complex 2 protects the heart from ischemic damage.
Circulation
; 128(19): 2132-44, 2013 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24008870
12.
Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity.
NPJ Parkinsons Dis
; 9(1): 4, 2023 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36646701
13.
Parkinson-causing mutations in LRRK2 impair the physiological tetramerization of endogenous α-synuclein in human neurons.
NPJ Parkinsons Dis
; 8(1): 118, 2022 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36114228
14.
Synphilin suppresses α-synuclein neurotoxicity in a Parkinson's disease Drosophila model.
Genesis
; 49(5): 392-402, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21584925
15.
Altered conformation of α-synuclein drives dysfunction of synaptic vesicles in a synaptosomal model of Parkinson's disease.
Cell Rep
; 36(1): 109333, 2021 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34233191
16.
Refolding of helical soluble α-synuclein through transient interaction with lipid interfaces.
FEBS Lett
; 592(9): 1464-1472, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29633780
17.
The protonation state of histidine 111 regulates the aggregation of the evolutionary most conserved region of the human prion protein.
Protein Sci
; 25(8): 1563-7, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27184108
18.
Fasudil attenuates aggregation of α-synuclein in models of Parkinson's disease.
Acta Neuropathol Commun
; 4: 39, 2016 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27101974
19.
PRAS40 prevents development of diabetic cardiomyopathy and improves hepatic insulin sensitivity in obesity.
EMBO Mol Med
; 6(1): 57-65, 2014 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24408966
20.
Small molecule-mediated stabilization of vesicle-associated helical α-synuclein inhibits pathogenic misfolding and aggregation.
Nat Commun
; 5: 5857, 2014 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25524885