Detalhe da pesquisa
1.
Azaindoles as Zinc-Binding Small-Molecule Inhibitors of the JAMM Protease CSN5.
Angew Chem Int Ed Engl
; 56(5): 1294-1297, 2017 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27981705
2.
Ligandability Assessment of IL-1ß by Integrated Hit Identification Approaches.
J Med Chem
; 67(10): 8141-8160, 2024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38728572
3.
Discovery of a selective and biologically active low-molecular weight antagonist of human interleukin-1ß.
Nat Commun
; 14(1): 5497, 2023 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37679328
4.
Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases.
J Med Chem
; 63(11): 5697-5722, 2020 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32073845