RESUMO
Lobomycosis (lacaziosis) is a chronic, granulomatous, fungal infection of the skin and subcutaneous tissues of humans and dolphins. To date, the causative agent, the yeast-like organism Lacazia loboi, has not been grown in the laboratory, and there have been no recent reports describing attempts to culture the organism. As a result, studies on the efficacy of therapeutics and potential environmental reservoirs have not been conducted. Therefore, the objective of the current study was to utilize both classical and novel microbiological methods in order to stimulate growth of Lacazia cells collected from dolphin lesions. This included the experimental inoculation of novel media, cell culture, and the use of artificial skin matrices. Although unsuccessful, the methods and results of this study provide important insight into new approaches that could be utilized in future investigations of this elusive organism.
Assuntos
Golfinho Nariz-de-Garrafa/microbiologia , Lacazia/crescimento & desenvolvimento , Lacazia/isolamento & purificação , Lobomicose/veterinária , Técnicas Microbiológicas/métodos , Animais , Oceano Atlântico , Granuloma/patologia , Histocitoquímica , Lobomicose/microbiologia , Lobomicose/patologia , MicroscopiaRESUMO
After discussing the rarity of male breast carcinoma, I present the case of a 75-year-old white man who, during an office visit for a second opinion regarding his eczema, was found to have breast cancer. (While examining the patient's integument, I found an inverted nipple and a subareolar mass.) I also discuss the need for dermatologists to emphasize to their patients the importance of complete general skin examinations. This case is, I believe, the first case of invasive primary male breast carcinoma to be reported in the dermatologic literature.
Assuntos
Neoplasias da Mama Masculina/patologia , Carcinoma Ductal de Mama/patologia , Eczema/diagnóstico , Linfonodos/patologia , Idoso , Biópsia por Agulha , Neoplasias da Mama Masculina/diagnóstico , Neoplasias da Mama Masculina/cirurgia , Carcinoma Ductal de Mama/diagnóstico , Carcinoma Ductal de Mama/cirurgia , Doença Crônica , Dermatologia/métodos , Seguimentos , Humanos , Metástase Linfática , Masculino , Mamografia , Mastectomia/métodos , Estadiamento de Neoplasias , Papel do Médico , Medição de Risco , Resultado do TratamentoAssuntos
Mordeduras e Picadas/complicações , Venenos de Cnidários/intoxicação , Eritema Nodoso/etiologia , Hidrozoários , Corticosteroides/uso terapêutico , Animais , Mordeduras e Picadas/terapia , Tratamento de Emergência , Humanos , Hipersensibilidade Tardia/tratamento farmacológico , Hipersensibilidade Tardia/imunologiaAssuntos
Melanoma/patologia , Neoplasias Cutâneas/patologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Melanoma/diagnóstico , Pessoa de Meia-Idade , Invasividade Neoplásica , Metástase Neoplásica , Estadiamento de Neoplasias , Autocuidado , Neoplasias Cutâneas/diagnósticoRESUMO
Numerous aquatic vertebrate species are known to cause cutaneous injury. While many of the injuries occur in regions that harbor such organisms, with the ability of people to travel long distances in short periods of time, these injuries may be seen worldwide. Also, with the increasing tendency of people to keep home aquariums, these injuries may occur anywhere. The majority of such injuries are minor and most go unreported. Some, however may be associated with morbidity and loss of life. Along with such injuries comes the potential for infection by bacteria, algae, or fungi. Some of these organisms are ubiquitous, others are specific to the aquatic environment. Toxins may be transferred from the offending organisms into the wound. Interestingly, some of these same toxins may be beneficial to treating some disease states in man.
Assuntos
Organismos Aquáticos , Mordeduras e Picadas/complicações , Dermatopatias/etiologia , Toxinas Biológicas/efeitos adversos , Ferimentos e Lesões/complicações , Animais , Aquicultura , Mordeduras e Picadas/etiologia , Briozoários , Peixes , Humanos , Microalgas , Animais de Estimação , Toxinas Biológicas/farmacologia , Ferimentos e Lesões/etiologiaRESUMO
Aquatic dermatoses encompass a broad spectrum of cutaneous injuries. These injuries may present through contact with invertebrate organisms such as jellyfish, sea urchins, corals, and molluscs. Each organism is equipped with a unique method of causing harm to man, therefore a myriad of presenting signs and symptoms should be recognized in order to initiate treatment. Aquatic injuries are not limited to areas of the world where these species originate. With the advent of rapid world travel and the hobby of home aquariums, dermatologists play a key role in the early diagnosis and treatment of such injuries. The method of injury, including a discussion of organism identification will be presented. Additionally, treatment of injuries caused by aquatic life will follow.