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1.
Odontostomatol Trop ; 33(131): 5-10, 2010 Sep.
Artigo em Francês | MEDLINE | ID: mdl-21328923

RESUMO

The authors report a case of glioma nasopalatine Multifoil in wallet, location-intra nasal and palatal left. The nasal glioma is a rare congenital malformation presenting as a nasal mass composed of neuroglial tissue heteropias resulting from an abnormality in embryonic development. It is a benign tumor that fits into the nosology of the masses of the midline. This abnormality arises primarily a diagnostic problem because often mistaken for a meningo-encephalocele or a nasal dermoid cyst. Localization nose and palate, an hourglass, is extremely rare if not exceptional; The computed tomography (CT) has enabled the accurate assessment of injury and has guided the choice of surgical technique. The resection was done successfully without recurrence. Histology examination of the surgical specimen confirmed the nature of astrocytic neuroglial tumor. The location of the tumor pedide palate to that of the left nostril is special and especially histological diagnosis of this congenital malformation.


Assuntos
Coristoma/congênito , Doenças Maxilares/congênito , Doenças Nasais/congênito , Palato/patologia , Diagnóstico Diferencial , Feminino , Humanos , Lactente , Obstrução Nasal/congênito
2.
Mali Med ; 35(1): 29-34, 2020.
Artigo em Francês | MEDLINE | ID: mdl-37978755

RESUMO

BACKGROUND: Surgical site infections (SSI) complicate most operations in developing countries. A variety of germs is responsible for it. The purpose of this study was to determine the incidence of surgical site infections and the bacteriological profile. PATIENTS AND METHODS: We conducted a prospective study for descriptive purposes. The included patients were treated between August 2016 and July 2017 in the Surgery B department of the University Hospital Center Point G. The study population consisted of all patients operated on and hospitalized for at least 72 hours. Patients who had an infection of the operative site were retained. The incidence of ISOs, the different bacterial strains and their susceptibility to antibiotics were studied. Data was analyzed on SPSS 12.0. RESULTS: The incidence of surgical site infections was 4.7%. The median age of the patients was 29.5 ± 4.34, the sex ratio was 1.66. The average time to onset of infections was 7.33 days. Of the samples taken, 4 bacterial strains were identified: Escherichia coli, Staphylococcus aureus, Acinobacter baumanii and Enterobacter spp. Isolated strains of Escherichia coli and Staphylococcus aureus were sensitive to Cefotaxim, Amikacin, Nitrofurantoin, but resistant to Ceftriaxon, Amoxicillin + Clavulanic acid. The species of Acinobacter baumanii and Enterococcus spp. Were sensitive to Colistin, but resistant to Ceftriaxone, Amoxicillin + clavulanic acid. CONCLUSION: Escherichia coli and Staphylococcus aureus are the main germs of the generally antibiotic-resistant ISOs commonly used in the service.


INTRODUCTION: Les infections du site opératoire (ISO) compliquent la plupart des opérations dans les pays en développement. Une diversité de germes en est responsable. Le but de cette étude était de déterminer l'incidence des infections du site opératoire et leur profil bactériologique. PATIENTS ET MÉTHODES: Nous avons réalisé une étude prospective à visée descriptive. Les patients inclus étaient pris en charge entre Aout 2016 et Juillet 2017 dans le service de chirurgie B du centre hospitalier universitaire du Point G. La population d'étude était constituée de tous les patients opérés et hospitalisés pendant au moins 72 heures. Les patients ayant présenté une infection du site opératoire étaient retenus. L'incidence des ISO, les différentes souches bactériennes et leur sensibilité aux antibiotiques ont été étudiées. Les données ont été analysées sur SPSS 12.0. RÉSULTATS: L'incidence des infections du site opératoire était de 4,7%. L'âge médian des patients était de 29,5 ans ±4,34, le sex ratio de 1,66. Le délai moyen d'apparition des infections était de 7,33 jours. Sur les prélèvements réalisés, 4 souches bactériennes étaient identifiées : Escherichia coli, Staphylococcus aureus, Acinobacter baumanii et Enterobacter spp. Les souches d'Escherichia coli et de Staphylococcus aureus isolées étaient sensibles au Cefotaxime, à Amikacine, à Nitrofurantoïne, mais résistantes à Ceftriaxone, à Amoxicilline+Acide clavulanique. Les espèces d'Acinobacter baumanii et d'Entérocoque spp étaient sensibles à Colistine, mais résistantes à Ceftriaxone, à Amoxicilline+Acide clavulanique. CONCLUSION: Escherichia coli et Staphylococcus aureus sont les principaux germes des ISO généralement résistants aux antibiotiques couramment utilisés dans le service.

3.
Mali Med ; 34(4): 11-14, 2019.
Artigo em Francês | MEDLINE | ID: mdl-35897200

RESUMO

PURPOSE: To describe the epidemiological, clinical and therapeutic aspects of acute surgical abdomens at the Koutiala Reference Health Center. PATIENTS AND METHOD: This was a prospective and descriptive study from August 1, 2017 to May 31, 2018. It included all patients operated on for acute abdomen in the General Surgery Department of the Koutiala Reference Health Center. The study did not include the nonoperated surgical acute abdomens, the non-surgical acute abdomens. Clavien-Dindo classification was used to evaluate complications. RESULTS: One hundred patients were registered. Acute surgical abdomens accounted for 8.4% of consultations (n = 1190), 27.7% of surgical procedures (n = 361) and 70% of surgical emergencies (n = 142). The average age was 34.4 years ± 18.5. Men were in the majority with 70%. The mean duration of change in symptomatology was 4.8 days ± 5.4. Patients consulted for abdominal pain (100%), fever (60%), vomiting (88%) and discontinuation of materials and gases (32%). The physical examination noted abdominal distension (53%), abdominal contracture (36%), abdominal defense (56%) and pain in the cul de sac of Douglas (95%). X-rays of the abdomen without preparation and abdominopelvic ultrasonography contributed to the diagnosis in 46% of cases and 18% of cases, respectively. Acute appendicitis (35%) was the most common etiology followed by acute peritonitis (31%) and acute intestinal obstruction (15%). We performed an appendectomy in 45 patients (45%), resection anastomosis (15%) and excision-suture (13%). The average duration of hospitalization was 4.7 days. The morbidity was 12%. According to the Clavien-Dindo classification, 9 patients were grade III and 3 grade V. The mortality was 3%. CONCLUSION: Acute surgical abdomens are the most common emergencies in our practice. The diagnosis is clinical and para-clinical most often. Morbidity and mortality remain elevated. The outcome of treatment depends on early management and mastery of abdominal surgery techniques.


BUT: Décrire les aspects épidémiologiques, cliniques et thérapeutiques des abdomens aigus chirurgicaux au Centre de Santé de Référence de Koutiala. PATIENTS ET MÉTHODES: Il s'agissait d'une étude prospective et descriptive allant du 1er Aout 2017 au 31 Mai 2018. Elle a porté sur tous les patients opérés pour abdomen aigu dans le service de chirurgie générale du centre de santé de référence de Koutiala. N'ont pas été retenus dans notre étude les abdomens aigus chirurgicaux non opérés, les abdomens aigus non chirurgicaux. La classification de Clavien-Dindo a été utilisée pour évaluer les complications. RÉSULTATS: Cent patients ont été enregistrés. Les abdomens aigus chirurgicaux ont représenté 8,4% des consultations (n=1190), 27,7% des interventions chirurgicales (n=361) et 70% des urgences chirurgicales (n=142). L'âge moyen était de 34,4 ans±18,5. Les hommes étaient majoritaires avec 70%. La durée moyenne d'évolution de la symptomatologie était de 4,8 jours±5,4. Les patients ont consulté pour douleur abdominale (100%), la fièvre (60%), les vomissements (88%) et l'arrêt des matières et des gaz (32%). L'examen physique a noté la distension abdominale (53%), la contracture abdominale(36%), la défense abdominale (56%) et la douleur au cul de sac de Douglas (95%). La radiographie de l'abdomen sans préparation et l'échographie abdominopelvienne ont contribué respectivement au diagnostic dans 46% des cas et 18% des cas. Les appendicites aigues(35%) étaient les étiologies les plus fréquentes suivies des péritonites aigues (31%) et les occlusions intestinales aigues (15%). Nous avons réalisé une appendicectomie chez 45 patients (45%), la résection anastomose (15%) et l'excision-suture (13%). La durée moyenne d'hospitalisation était de 4,7 jours. La morbidité était de 12%. Selon la classification de Clavien-Dindo, 9 patients étaient de grade III et 3 de grade V. La mortalité était de 3%. CONCLUSION: Les abdomens aigus chirurgicaux sont des urgences les plus fréquentes dans notre pratique. Le diagnostic est clinique et para clinique le plus souvent. La morbi-mortalité reste élever. Le résultat du traitement dépend de la prise en charge précoce et la maitrise des techniques de chirurgie abdominale.

4.
Mali Med ; 34(3): 20-23, 2019.
Artigo em Francês | MEDLINE | ID: mdl-35897222

RESUMO

PURPOSE: the aim of this study was to evaluate the clinical and therapeutic aspects of non-traumatic digestive perforations at the Koutiala Reference Health Center. PATIENTS AND METHODS: This was a prospective and descriptive study from August 1, 2017 to December 31, 2018. Patients admitted and operated on for non-traumatic digestive perforation were included. The parameters studied were age, sex, frequency, clinical aspects, etiologies, treatment and operative follow-up. RESULT: Sixty-one patients were registered. Non-traumatic digestive perforations accounted for 78.2% of cases of acute peritonitis (n = 78). Men were in the majority with 73.8%. The average age was 34.5 years old. The symptomatology was represented by abdominal pain in all patients, vomiting in 56 patients and fever in 42 patients. The mean duration of evolution of the symptomatology was 5.5 days. On physical examination, the most common signs were abdominal contracture with 81.9%, disappearance of prehepatic maturation (52.4%) and pain in rectal examination (95.1%). Radiological pneumoperitoneum was found in 39 patients. The serodiagnosis of Widal was positive in 15 cases. The etiologies were dominated by perforation of infectious origin with 77.0% (46). The perforation was ileal in 28 patients, appendicular in 18 patients and gastroduodenal in 11 patients. Excision-suturing of the perforation was done in 30 patients, resection anastomosis in 8 patients and appendectomy in 18 patients. Morbidity and mortality were respectively 14.7% and 6.5%. CONCLUSION: Non-traumatic digestive perforations are the first cause of peritonitis in our department. The ileal seat is the most common and is most often secondary to typhoid fever. Morbidity and mortality remain high and this result is a reflection of late diagnosis which is the main factor of severity of digestive perforations.


BUT: Evaluer les aspects cliniques et thérapeutiques des perforations digestives non traumatiques au Centre de Santé de Référence de Koutiala. PATIENTS ET MÉTHODES: Il s'agissait d'une étude prospective et descriptive allant du 1erAoût 2017 au 31 décembre 2018. Les patients admis et opérés pour perforation digestive non traumatique étaient inclus. Les paramètres étudiés étaient l'âge, le sexe, la fréquence, les aspects cliniques, les étiologies, le traitement et les suites opératoires. RÉSULTAT: Soixante-un patients ont été enregistrés. Les perforations digestives non traumatiques ont représenté78,2% de causes de péritonite aigue (n=78). Les hommes étaient majoritaires avec 73,8%.L'âge moyen était de 34,5 ans. La symptomatologie était représentée par la douleur abdominale chez tous les patients, les vomissements chez 56 patients etla fièvre chez 42 patients. La durée moyenne d'évolution de la symptomatologie était de 5,5 jours. A l'examen physique, les signes les plus fréquents étaient la contracture abdominale avec 81,9%, la disparition de la matité pré hépatique (52,4%) et la douleur au toucher rectal (95,1%). Un pneumopéritoine radiologique a été trouvé chez 39 patients. Le sérodiagnostic de Widal était positif dans 15 cas. Les étiologies étaient dominées par la perforation d'origine infectieuseavec77,0% (46). La perforation était iléal chez 28 patients, appendiculaire chez 18 patients et gastroduodénale chez 11 patients. L'excision-suture de la perforation a été faite chez 30 patients, la résection anastomose chez 8 patients et l'appendicectomiechez18 patients. La morbidité et la mortalité ont été respectivement de 14,7%de 6,5%. CONCLUSION: Les perforations digestives non traumatiques sont la première cause de péritonite dans notre service. Le siège iléal est le plus fréquent et qui est secondaire le plus souvent à la fièvre typhoïde. La morbi-mortalité reste élever et ce résultat est le reflet du diagnostic tardif qui constitue le principal facteur de gravité des perforations digestives.

5.
Morphologie ; 92(299): 176-80, 2008 Dec.
Artigo em Francês | MEDLINE | ID: mdl-19026585

RESUMO

OBJECTIVE: The goal of this survey was to study the level of emergence of the external carotid artery and the origin of its collateral branches about a dissection of 30 cadavers subjects of West Africa. MATERIAL AND METHOD: We dissected to the laboratory of Abidjan anatomy 30 cool adults' cadavers corresponding to 28 men and two women. At these 30 cadavers, we dissected 60 external carotids. We studied the level of bifurcation of the carotid artery in relation to hyoid bone and thyroid cartilage and the level of the emergence of the collaterals branches of the external carotid artery according to classic description. RESULTS: The origin of the external carotid artery was variable: in 46 cases (75%), the origin was between the hyoid bone and the thyroid cartilage; in 10 cases (15%), this origin was below the thyroid cartilage and in four cases (13%), this origin was over to the hyoid bone. In 46.5% of cases, we find five collaterals branches of the external carotid artery. According to classic description, we find some variations of the emergence of collateral arteries: the facial artery is not below the lingual artery in 28 cases (46.5%); the ascending pharyngeal artery do not emerge at the same level of lingual artery in 46 cases (76.5%) and in 44 cases (73%), the occipital artery do not emerge of the same level of the facial artery. CONCLUSION: Levels of collateral branch emergence in population of West Africa is variable. It is important to know that for practice cervical surgery safety.


Assuntos
Artéria Carótida Externa/anatomia & histologia , Adulto , Côte d'Ivoire , Feminino , Variação Genética , Cabeça/irrigação sanguínea , Humanos , Osso Hioide/anatomia & histologia , Complicações Intraoperatórias/prevenção & controle , Masculino , Pescoço/irrigação sanguínea , Pescoço/cirurgia , Cartilagem Tireóidea/anatomia & histologia
6.
Dakar Med ; 53(3): 198-204, 2008.
Artigo em Francês | MEDLINE | ID: mdl-19626791

RESUMO

INTRODUCTION: The sensibility of bacteria in a general way decreased a lot, staphylococci present a resistance to the penicillin in more than 80% of the cases. The aim of our work was to determine the level of sensibility of staphylococci, particularly that of resistant Staphylococcus aureus to Meticilline (SARM). MATERIAL AND METHODS: It is a retrospective study concerning the profile of sensibility of the isolated strains of staphylococci of diverse pathological products.The antibiogramme was realized according to the classic technique and for the test in the oxacilline, the Mueller Hinton + 5% of NaCl was used. RESULTS: during the period of study 1296 strains of staphylococcus were isolated, 153 from hospital Staphylococcus aureus were little sensitive to the penicillin G (10%); however the oxacilline, the gentamicine and the erythromycine were very active (more than 80% of sensibility.The meticillino-sensitive Staphylococcus aureus were also sensitive to the gentamycine, erythromycine and ciprofloxacine; the character of meticillino resistant did not influence the activity of antibiotics as pristinamycin and the vancomycine (100%); however we note a resistance crossed with the erythromycine in more than 95% of the cases. CONCLUSION: the existence although weak of the strains meticillino resistant brings us to propose a regular surveillance of the SARM and to hold as active antibiotics of first line the pristinamycine, ciprofloxacine, gentamicine, with vancomycine as the alternative of last choice in a hospital environment.


Assuntos
Antibacterianos/farmacologia , Farmacorresistência Bacteriana Múltipla , Infecções Estafilocócicas/tratamento farmacológico , Humanos , Estudos Retrospectivos , Staphylococcus
7.
Mali Med ; 33(4): 6-9, 2018.
Artigo em Francês | MEDLINE | ID: mdl-35897235

RESUMO

INTRODUCTION: The brachial plexus consists of the ventral twigs of the last four cervical nerves and the first thoracic nerve. It ensures the motor and sensitive innervations of the thoracic limb. AIM: Our goal was to describe the brachial plexus of the cervical region to the middle third of the arm. METHODOLOGY: We conducted a prospective study at the anatomy Laboratory of the Faculty of Medicine and Dentistry in Bamako from September 2016 to October 2017. We dissected the brachial plexus (PB) of 13 fresh adult corpses on both sides. The inclusion criteria were: Fresh adult corpses with cervical regions and brachial without scarring. The injected or scar-carrying corpses were not included in the cervical and brachial regions. RESULTS: Twenty-six brachial plexus of which 18 bp in men and 8 bp in women were dissected. The average age of the subjects was 42 years (extreme: 18 and 70 years). We noted nerve block variations in 3.8%, fascicular in 3.8% and late terminal in 73.1%. The involvement of the anterior branch of the fourth spinal nerve (C4) was found in 46.2%. CONCLUSION: The brachial plexus is the seat of many anatomical variations whose knowledge is indispensable to treat its lesions.


INTRODUCTION: Le plexus brachial est constitué des rameaux ventraux des quatre derniers nerfs cervicaux et du premier nerf thoracique. Il assure l'innervation motrice et sensitive du membre thoracique. BUT: Notre but était de décrire le plexus brachial de la région cervicale au tiers moyen du bras. MÉTHODE: nous avons réalisé une étude prospective au laboratoire d'anatomie de la Faculté de Médecine et d'Odontostomatologie de Bamako de septembre 2016 à octobre 2017. Nous avons disséqué des deux côtés les plexus brachiaux (PB)de 13 cadavres frais d'adultes. Les critères d'inclusion étaient : cadavres frais d'adulte avec les régions cervicale et brachiale sans cicatrice. N'ont pas été inclus les cadavres injectés ou porteurs de cicatrice au niveau des régions cervicale et brachiale. RÉSULTATS: Vingt-six plexus brachiaux dont 18 PB chez les hommes et 8 PB chez les femmes ont été disséqués. L'âge moyen des sujets était de 42 ans (extrême : 18 et 70 ans). Nous avons noté des variations tronculaires dans 3,8%, fasciculaires dans 3,8% et en fin terminales dans 73,1%. La participation du rameau antérieur du quatrième nerf spinal cervical (C4) a été trouvée dans 46,2%. CONCLUSION: Le plexus brachial est le siège de nombreuses variations anatomiques dont la connaissance est indispensable pour traiter ses lésions.

8.
Morphologie ; 90(291): 175-9, 2006 Dec.
Artigo em Francês | MEDLINE | ID: mdl-17432048

RESUMO

INTRODUCTION: Dividing the subscapularis muscle along its fibers axis allows approaching the glenohumeral joint. The more medial its division, the more possible injury of its nerve supply. AIM: The aim of our study was to assess the subscapularis nerve supply through cartography of the entry points of subscapularis nerves from simple landmarks, reproducible by triangulation. MATERIAL AND METHODS: On 18 formalin-preserved shoulders, after dissection of the subscapularis nerves, distances were measured between entry points of subscapularis nerves and the following landmarks: center of the minor tubercle (tm), upper and lower poles of the glenoid cavity (cgs and cgi), apex of the coracoid process (pc). RESULTS: There were in average 3.33 subscapularis nerves (2-4). These different nerves split most often before entering subscapularis muscle; there were in average 5.05 entry points (3-6). Distances between entry points and clinical landmarks were as follows: cgs, 3.9-6.45 cm; cgi, 3.7-5.54 cm; tm, 5.9-7.15 cm; pc, 4.9-7.66 cm. Reporting these measurements onto a frame allowed to show that all these points were located in average medially to the scapular notch and at more than 3 cm from the anterior border of the glenoid cavity. CONCLUSION: If the transverse division does not extend farther than 3 cm from the anterior border of the glenoid cavity and from the medial border of the root of the coracoid process, there should not be any injury of the subscapularis nerves.


Assuntos
Músculo Esquelético/inervação , Ombro , Cadáver , Feminino , Humanos , Masculino
9.
Odontostomatol Trop ; 29(114): 23-7, 2006 Jun.
Artigo em Francês | MEDLINE | ID: mdl-16910114

RESUMO

The opportinistics complaints of the AIDS occur all along the episode of the infection and depend on the individual's body immunity and on the existence or no of an anti-retroviral treatment. The buccal appearences on the face are relatively frequent. They are dominated by the buccal mycosis, the lymphatic ganglion's complaints, the inflammation of gums and buccal mucous, and the tooth decay in our context. Some authors suggest a classification that can make easy their study and treatment. Complaints like the herpes simplex infection, the herpes zoster infection, are usually found during the symptomatic stage non AIDS, whereas others like KAPOSI's disease are typical to AIDS disease. The availlability of an anti-retroviral treatment and a specialized one strenghten the efficiency of the reimbursement and improve the prognosis.


Assuntos
Infecções Oportunistas Relacionadas com a AIDS/diagnóstico , Doenças da Boca/diagnóstico , Síndrome da Imunodeficiência Adquirida/tratamento farmacológico , Adulto , Instituições de Assistência Ambulatorial , Fármacos Anti-HIV/uso terapêutico , Burkina Faso , Candidíase Bucal/diagnóstico , Escolaridade , Feminino , Infecções por HIV/tratamento farmacológico , Hospitais Universitários , Humanos , Doenças Linfáticas/diagnóstico , Masculino , Pessoa de Meia-Idade , Ocupações , Estudos Prospectivos , Fatores Sexuais , Fatores Socioeconômicos , Estomatite/diagnóstico , Estomatite Herpética/diagnóstico
10.
Morphologie ; 89(285): 76-81, 2005 Jun.
Artigo em Francês | MEDLINE | ID: mdl-16110743

RESUMO

PURPOSE: The aim of this study is to precise the variations of portal vein branches and also to elucidate anatomic basis of partial hepatectomy. MATERIAL AND METHODS: Thirty-two post-mortem specimens, with ages ranged from one day to sixty-five years in both two sexes, were dissected. Latex and Rhodopas were used for visualizing and drawing the portal vein course and its branches. RESULTS: Nine types of different variations of portal vein branches were observed. Most of cases were similar to those previously reported in literature. But four types must be especially noted, because they were not available in literature. DISCUSSION: this study updates the anatomy of portal vein and its tributaries, and also finds out four types of distribution which must be known by surgeons with regards to partial hepatectomy.


Assuntos
Veia Porta/anormalidades , Veia Porta/anatomia & histologia , Adolescente , Adulto , Idoso , Cadáver , Criança , Pré-Escolar , Feminino , Variação Genética , Humanos , Lactente , Recém-Nascido , Masculino , Pessoa de Meia-Idade
11.
AIDS ; 3(8): 509-12, 1989 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-2508711

RESUMO

In September 1987, a seroprevalence study of HIV-1 and HIV-2 infection was conducted among 956 people from different groups in Abidjan, Côte d'Ivoire. Groups examined were hospitalized patients (Internal Medicine and Infectious Disease Departments, Centre Hospitalier Universitaire de Treichville, Abidjan), outpatients at tuberculosis treatment centers, blood donors, women attending an antenatal clinic, and patients attending sexually transmitted disease (STD) clinics. Total HIV infection prevalence ranged from 10% in STD clinic patients and pregnant women to 45% in hospitalized patients on an infectious diseases service. Within groups, HIV-1 infection was 2-6.5 times more prevalent than infection with HIV-2. One-quarter of HIV-seropositive people were serologically reactive to both HIV-1 and HIV-2 on enzyme-linked immunosorbent assay and Western blot. Clinical conditions previously observed in patients with HIV-1 infection were observed in people infected with HIV-2 only, as well as in those with HIV-1 infection and dual serologic reactivity. An isolate of HIV-2 was obtained on culture from a person with wasting disease and chronic fever. The results of this study suggest that infection with HIV-1 and HIV-2 is epidemic in Côte d'Ivoire, and that HIV-2 may be associated with AIDS.


Assuntos
Síndrome da Imunodeficiência Adquirida/epidemiologia , HIV-1/imunologia , HIV-2/imunologia , Síndrome da Imunodeficiência Adquirida/imunologia , Síndrome da Imunodeficiência Adquirida/microbiologia , Adolescente , Adulto , África Ocidental , Idoso , Idoso de 80 Anos ou mais , Western Blotting , Ensaio de Imunoadsorção Enzimática , Feminino , Anticorpos Anti-HIV/análise , Soropositividade para HIV/epidemiologia , Soropositividade para HIV/imunologia , HIV-1/isolamento & purificação , HIV-2/isolamento & purificação , Humanos , Masculino , Pessoa de Meia-Idade
12.
Am J Trop Med Hyg ; 45(3): 297-308, 1991 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-1928564

RESUMO

The protective effect of African IgG antibodies against Plasmodium falciparum malaria was investigated by passive transfer in Thai patients. Sera from 333 African adults were collected in the Cote d'Ivoire and subjected to extensive screening. One hundred fifty-three samples were discarded for safety reasons, and IgG was extracted from those remaining under conditions allowing their use by the intravenous (iv) route. Eight Thai patients with P. falciparum parasitemia were treated by iv inoculation of the IgG: six with a 100 mg/kg dose given over three days, one with a single 20 mg/kg dose, and one with a single 200 mg/kg dose. To ensure a safety margin of at least 48 hours, subjects were chosen among patients having a recrudescent parasitemia following quinine treatment failure at the RI level. At that stage, symptoms were mild or absent and parasitemia was low but increasing (range 4, 200-9,000/microliters). The IgG pool exerted a profound, stage-specific, but non-sterilizing effect on each of the strains tested, and proved to be safe. Asexual parasitemia decreased by a mean 728-fold (range 46-1,086), while gametocytes were unaffected. Clearance of parasites and symptoms was as fast or faster than with drugs, and was consistent in the eight patients treated, suggesting that target antigens were equally expressed in geographically remote isolates. In peripheral blood smears, no mature forms were seen at any time during the followup, which does not support the hypothesis that reversal of cytoadherence occurred. After the disappearance of the transferred antibodies, recrudescent parasites from three patients were found to be susceptible to the same extent (mean decrease of 1,310-fold) to the same IgG preparation, indicating that selection of parasites able to escape the effect of antibodies had not occurred. No adverse side-effects were detected during the followup, which lasted one year.


Assuntos
Imunização Passiva , Imunoglobulina G/uso terapêutico , Imunoglobulinas Intravenosas/uso terapêutico , Malária Falciparum/terapia , Plasmodium falciparum/imunologia , Adulto , Animais , Anticorpos Antiprotozoários/uso terapêutico , Seguimentos , Humanos , Contagem de Leucócitos , Fígado/patologia , Malária Falciparum/imunologia , Plasmodium vivax/crescimento & desenvolvimento , Baço/patologia
13.
Gastroenterol Clin Biol ; 15(10): 711-6, 1991.
Artigo em Francês | MEDLINE | ID: mdl-1667767

RESUMO

Only a few reports have established the importance of chronic gastritis and Helicobacter pylori infection in Africa. The aim of this study was to ascertain the prevalence of chronic gastritis and Helicobacter pylori infection in a symptomatic population in Abidjan, Côte-d'Ivoire. The study included 277 consecutive patients referred for gastroscopy. Two hundred nine patients complained of abdominal pain without gastroduodenal ulcer or cancer: 26 had a duodenal ulcer, 23 had a gastric ulcer, and 6 had gastric cancer. The remaining 14 patients underwent gastroscopy for various other reasons. Chronic gastritis was present in 89 percent of cases, of which 96 percent showed signs of activity. There were four cases of lymphocytic gastritis. Patients with antral chronic gastritis were older (39.43 +/- 14.3 years) than those with normal antral mucosa (33.7 +/- 12 years, P less than 0.05). Helicobacter pylori was present in 91.3 percent of cases, representing all patients with active chronic gastritis, and 60 percent of the patients with normal gastric mucosa. Chronic gastritis was present in 86 percent of patients with abdominal pain, in 100 percent of those with duodenal of gastric ulcer, and Helicobacter pylori were observed in 90, 100, and 91 percent of the same patient groups, respectively. This study demonstrates the high prevalence of chronic gastritis and the very high level of Helicobacter pylori infection in Ivorian patients complaining of various gastrointestinal symptoms. The usefulness and feasibility of therapeutic trials still have to be investigated.


Assuntos
Gastrite Atrófica/epidemiologia , Gastrite/epidemiologia , Infecções por Helicobacter/epidemiologia , Helicobacter pylori/isolamento & purificação , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Doença Crônica , Côte d'Ivoire/epidemiologia , Endoscopia Gastrointestinal , Feminino , Gastrite/diagnóstico por imagem , Gastrite/microbiologia , Gastrite Atrófica/diagnóstico por imagem , Gastrite Atrófica/microbiologia , Infecções por Helicobacter/diagnóstico por imagem , Infecções por Helicobacter/microbiologia , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Radiografia
14.
Bull Soc Pathol Exot ; 95(4): 287-91, 2002 Nov.
Artigo em Francês | MEDLINE | ID: mdl-12596381

RESUMO

OBJECTIVE: A certain number of authors have in literature pointed out multifocal forms of Buruli ulcer but no study was ever dedicated to them. The purpose of this study is to be more specific about the clinical aspects and to show how difficult it is for those multifocal forms of Buruli ulcer to be operated on. METHOD: The 11 patients who were accepted for the study were subjected to an interrogation, a thorough clinical examination, research of BAAR in ulcers and operative pieces with a direct examination after Ziehl-Neelsen colouring. Each of these patients underwent a surgical treatment under general anaesthesia or spinal anaesthesia depending on the seat of the lesions under cover of pre and post operative therapy by antibiotics. RESULTS: Initial lesions preferentially were located at limbs level; new foci appeared within an average period of 3 months, ranging from 1 to 15 months in some cases. All body parts could be the seats of secondary foci. Depending on the patients, the number of foci varied from 3 to 7. Furthermore, amputation has been necessary for the complete healing of four patients. The average operation was 2.4 by patient ranged from 2 to 5. We observed the healing of all the patients within an average hospitalisation time of 6.3 months running sometimes from 4 to 13 months. In addition to amputations, 4 patients presented after-effects as articular stiffness, retractions of the hand's dorsal face and knee's retraction. CONCLUSION: Those multifocal forms can, with good reason, be considered as malignant form of Buruli ulcer.


Assuntos
Infecções por Mycobacterium não Tuberculosas/patologia , Infecções por Mycobacterium não Tuberculosas/cirurgia , Mycobacterium ulcerans , Úlcera Cutânea/patologia , Úlcera Cutânea/cirurgia , Adolescente , Adulto , Idoso , Amputação Cirúrgica , Antibacterianos/uso terapêutico , Criança , Pré-Escolar , Terapia Combinada , Côte d'Ivoire/epidemiologia , Doenças Endêmicas/estatística & dados numéricos , Feminino , Humanos , Tempo de Internação/estatística & dados numéricos , Masculino , Anamnese , Pessoa de Meia-Idade , Infecções por Mycobacterium não Tuberculosas/epidemiologia , Infecções por Mycobacterium não Tuberculosas/microbiologia , Exame Físico , Estudos Prospectivos , Transplante de Pele , Úlcera Cutânea/classificação , Úlcera Cutânea/microbiologia , Resultado do Tratamento , Cicatrização
15.
Bull Soc Pathol Exot ; 91(2): 156-7, 1998.
Artigo em Francês | MEDLINE | ID: mdl-9642472

RESUMO

One case of total splenic atrophy is reported in a patient with SS homozygous sickle-cell disease presenting no related malformation, thus recalling the IVEMARK syndrome. An abdominal echography and computed tomography are indispensable in order to confirm the absence of the anatomic spleen; this makes for a better follow-up of sickle-cell disease.


Assuntos
Anemia Falciforme/patologia , Baço/anormalidades , Adolescente , Anemia Falciforme/diagnóstico por imagem , Anemia Falciforme/genética , Homozigoto , Humanos , Tomografia Computadorizada por Raios X , Ultrassonografia
16.
Bull Soc Pathol Exot ; 91(3): 229-31, 1998.
Artigo em Francês | MEDLINE | ID: mdl-9773197

RESUMO

The authors examine radiographic aspects of osteo-articular and soft tissue lesions on the basis of 30 files of in-patients suffering from Buruli ulcers. They specify the chronology and precociousness of certain signs: soft tissue lesions, bone demineralization, periostal apposition two months after the beginning of signs, and later osteolysis and joint complications. These lesions are not specific and occur contiguously to soft tissue lesions. The authors specify the part of secondary-infection germs in the appearance of bone lesions.


Assuntos
Doenças Ósseas/microbiologia , Artropatias/microbiologia , Infecções por Mycobacterium não Tuberculosas/diagnóstico por imagem , Mycobacterium ulcerans , Úlcera Cutânea/microbiologia , Adolescente , Infecções Bacterianas , Doenças Ósseas/diagnóstico por imagem , Feminino , Humanos , Artropatias/diagnóstico por imagem , Masculino , Osteólise/diagnóstico por imagem , Osteólise/microbiologia , Radiografia , Estudos Retrospectivos , Superinfecção
17.
Rev Med Interne ; 14(2): 89-92, 1993 Feb.
Artigo em Francês | MEDLINE | ID: mdl-8378631

RESUMO

Pain induced by pinching the peritoneum betrays a pathology of that membrane. It is absent when the peritoneum is perfectly healthy. Pain is elicited by a special palpation technique. Clinically and statistically, the presence of this pain is pathognomonic, but it does not inform on the aetiology. In the present study the most frequent causes of positive abdominal peritoneal pinching test were peritoneal tuberculosis, followed by portal hypertension with or without liver cirrhosis.


Assuntos
Dor/etiologia , Palpação/métodos , Doenças Peritoneais/diagnóstico , Adulto , Feminino , Humanos , Masculino , Peritônio , Pesquisa
18.
J Radiol ; 85(5 Pt 1): 639-42, 2004 May.
Artigo em Francês | MEDLINE | ID: mdl-15205656

RESUMO

OBJECTIVES: To determine the value of perineal sonography in the diagnosis of urethral stenosis and evaluation of surrounding fibrosis. Materials and methods. Fifty-eight healthy subjects underwent urethral sonography. Thirty-two patients with suspected urethral stenosis underwent sonography after retrograde distension of the urethra using normal saline and retrograde urethrogram and voiding cystourethrogram. RESULTS: The mean diameters of the healthy urethra varied from 11 to 15 mm. The mean thickness of normal periurethral tIssue was between 2 and 4mm. Sonography detected 34 stenoses (97.4%). The length of the stenosis was significantly longer at sonography compared to retrograde urethrogram and voiding cystourethrogram. No significant difference was found between both techniques when measuring urethral diameter. In all cases, the thickness of periurethral tIssues was greater at the stenotic level than at a normal level, irrespective of the involved segment. There was no correlation between the thickness of periurethral tIssues and the degree of stenosis. CONCLUSION: Urethral sonography is a method that permits diagnosis of urethral stenosis and evaluation of periurethral fibrosis. It may replace retrograde urethrogram and voiding cystourethrogram in the diagnosis of post infectious stenosis.


Assuntos
Períneo , Estreitamento Uretral/diagnóstico por imagem , Adulto , População Negra , Estudos de Casos e Controles , Côte d'Ivoire , Diagnóstico Diferencial , Fibrose , Humanos , Masculino , Pessoa de Meia-Idade , Seleção de Pacientes , Estudos Prospectivos , Valores de Referência , Sensibilidade e Especificidade , Índice de Gravidade de Doença , Ultrassonografia/métodos , Ultrassonografia/normas , Estreitamento Uretral/classificação , Estreitamento Uretral/patologia , Urodinâmica , Urografia/métodos , Urografia/normas
19.
Ann Urol (Paris) ; 37(5): 223-8, 2003 Oct.
Artigo em Francês | MEDLINE | ID: mdl-14606306

RESUMO

Studies on the anatomy of the renal arteries in Black Africans being scarce, the authors have made their contribution to the knowledge of the renal arteries. They have provided a comparison between the anatomy of the renal arteries studied in the literature in relation to a white patient and black patient. It is a prospective study based on the change in the number of the renal arteries of 44 Black Africans' maccabees quite fresh, not yet embalmed that have been dissected in order, as received in the anatomy laboratory of Abidjan. That work has allowed to notice some results that are more or less similar to those revealed in the literature, i.e. in 80% of the cases, the kidney is irrigated by an artery, and in 20% of the cases, we have more than one artery for one kidney. No kidney is vascularized by more than two arteries. These results underline how important it is to have good anatomical knowledge of this region in renal surgery. This is possible thanks to medical imagery and arteriography which helps in preventing operative accidents and in preserving the kidney.


Assuntos
Rim/irrigação sanguínea , Artéria Renal/anatomia & histologia , Adulto , População Negra , Cadáver , Criança , Côte d'Ivoire , Humanos , Recém-Nascido
20.
Sante ; 7(3): 169-72, 1997.
Artigo em Francês | MEDLINE | ID: mdl-9296807

RESUMO

A prospective study of 100 newborns and young babies suffering from purulent meningitis was carried out over a period of 11 months in the radiology department of CHU in Treichville. All the children included in the study were hospitalised in the pediatric department of the CHU. We found cerebral complications in 76% of cases. The most frequent complication was ventricular dilation which occurred in 82.6% of cases. Pericerebral bleeding occurred in 9.3%, cerebral ischemia in 3.5%, brain abscesses in 2.3% and ventriculitis in 2.3% of cases. Our study demonstrated the two important uses of trans-fontanelle ultrasound scans in the study of meningitis: (i) in diagnosis, for the detection of cerebral complications; (ii) in treatment, interventional use of ultrasound makes it possible to evacuate intra-cranial septic fluids.


Assuntos
Suturas Cranianas/diagnóstico por imagem , Meningites Bacterianas/diagnóstico por imagem , Côte d'Ivoire , Humanos , Lactente , Recém-Nascido , Meningites Bacterianas/complicações , Meningites Bacterianas/terapia , Estudos Prospectivos , Reprodutibilidade dos Testes , Supuração , Ultrassonografia , Saúde da População Urbana
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