RESUMO
A major challenge for Chilean salmon farming is infestation by the ectoparasite Caligus rogercresseyi. In addition, there is evidence that a loss of chemotherapeutic treatment efficacy against important fish pathogens is occurring in salmon farming, including antiparasitic efficacy. Currently, there are known techniques that allow the determination of the susceptibility profile of parasites to antiparasitic treatment. However, there is scarce information about both threshold values and categorization of antiparasitic susceptibility for C. rogercresseyi. Bioassay technique allowed the determination of both mean values and the natural variation of EC50%, which were contrasted with available susceptibility thresholds. Results allowed to determine that parasites from the native fish host, Eleginops maclovinus, are susceptible to azamethiphos, deltamethrin and cypermethrin treatments, showing a high susceptibility profile to antiparasitics.
Assuntos
Antiparasitários/farmacologia , Copépodes/efeitos dos fármacos , Ectoparasitoses/veterinária , Doenças dos Peixes/prevenção & controle , Perciformes , Animais , Ectoparasitoses/parasitologia , Ectoparasitoses/prevenção & controle , Feminino , Doenças dos Peixes/parasitologia , Masculino , Nitrilas/farmacologia , Organotiofosfatos/farmacologia , Piretrinas/farmacologiaRESUMO
Large vessel vasculitis and particularly Temporal Arteritis are systemic diseases that may affect the aorta and its major branches, mainly involving extra cranial branches of the carotid artery. We report a 72-year-old man presenting with weight loss, fever and malaise. Positron emission computed tomography (PET CT) showed an extensive inflammation of the aorta and its major branches. Temporal artery biopsy confirmed the presence of vasculitis with granulomas. Treatment with a high dose of steroids had an excellent clinical response. This case underscores the utility of PET CT in the assessment of this disease.
Assuntos
Aortite/diagnóstico por imagem , Aortite/patologia , Arterite de Células Gigantes/diagnóstico por imagem , Arterite de Células Gigantes/patologia , Idoso , Aortite/tratamento farmacológico , Biópsia , Arterite de Células Gigantes/tratamento farmacológico , Humanos , Masculino , Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada , Artérias Temporais/patologiaRESUMO
Large vessel vasculitis and particularly Temporal Arteritis are systemic diseases that may affect the aorta and its major branches, mainly involving extra cranial branches of the carotid artery. We report a 72-year-old man presenting with weight loss, fever and malaise. Positron emission computed tomography (PET CT) showed an extensive inflammation of the aorta and its major branches. Temporal artery biopsy confirmed the presence of vasculitis with granulomas. Treatment with a high dose of steroids had an excellent clinical response. This case underscores the utility of PET CT in the assessment of this disease.
Assuntos
Humanos , Masculino , Idoso , Aortite/patologia , Aortite/diagnóstico por imagem , Arterite de Células Gigantes/patologia , Arterite de Células Gigantes/diagnóstico por imagem , Aortite/tratamento farmacológico , Artérias Temporais/patologia , Arterite de Células Gigantes/tratamento farmacológico , Biópsia , Tomografia por Emissão de Pósitrons combinada à Tomografia ComputadorizadaRESUMO
La colitis ulcerosa, antes aparentemente excepcional entre nosotros, ha llegado a ser una afección relativamente común. Se analizan los recursos terapéuticos disponibles, los que utilizados adecuadamente han permitido modificar substancialmente la evolución y el pronóstico de la enfermedad.Entre ellos destacan los corticoides los que, después de 40 años, siguen siendo el principal pilar del tratamiento de la colitis ulcerosa. A ellos se han agregado la asulfidina y la cirugía, recursos terapéuticos en relación a los cuales se han realizado evidentes progresos. En cuanto a la asulfidina se han incorporado nuevos preparados o derivados de administración tanto oral como rectal que conservan su eficacia, reduciendo sus efectos laterales. La técnica quirúrgica ha experimentado evidentes progresos en lo que respecta a continencia y a reducción de las secuelas en el funcionamiento sexual. Ello se ha logrado al reemplazar la ileostomía definitiva por la íleo-rectostomía y en particular por la íleo-anastomía.