RESUMO
Choledocholithiasis is a common presentation of symptomatic cholelithiasis that can result in biliary obstruction, cholangitis, and pancreatitis. A systematic English literature search was conducted in PubMed to determine the appropriate management strategies for choledocholithiasis. The following clinical spotlight review is meant to critically review the available evidence and provide recommendations for the work-up, investigations as well as the endoscopic, surgical and percutaneous techniques in the management of choledocholithiasis.
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Procedimentos Cirúrgicos do Sistema Biliar/métodos , Colangiopancreatografia Retrógrada Endoscópica/métodos , Coledocolitíase/cirurgia , Humanos , Resultado do TratamentoRESUMO
PURPOSE: Separation of the components has become the standard of care for abdominal wall reconstruction, especially in the setting of infected, previously infected, or contaminated wounds. Although the safety and efficacy of this technique have been established, less is known about long-term outcomes. This article focuses on the management of recurrent hernia after components separation for abdominal wall reconstruction. METHODS: We performed a retrospective, institutional review board-approved study of components separation for abdominal wall reconstruction at an academic medical center, over a 10-year period. RESULTS: Between 2000 and 2009, we performed components separation in 136 patients (mean follow-up, 4.4 years). Twenty-six patients (19.1%) developed recurrent hernia (mean age, 49.8 years; body mass index, 30.7; previous abdominal operations, 3.5; hernia size, 342 cm; length of stay, 9.1 days). Mean time to recurrence was 319 days. Of the 16/26 patients who underwent repair of recurrence, 15 had successful repair, leaving 11/136 patients (8.1%) with persistent hernia. Of the 26 recurrences, 22 (85%) occurred within the first half of the study. Repair of recurrent hernias was accomplished by placement of additional mesh in 14/15 patients. CONCLUSIONS: Recurrent hernia after components separation may be related to procedural learning curves and can be successfully treated through repeat repair, yielding high rates of successful abdominal wall reconstruction.
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Parede Abdominal/cirurgia , Hérnia Ventral/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Deiscência da Ferida Operatória/cirurgia , Parede Abdominal/fisiopatologia , Centros Médicos Acadêmicos , Adulto , Idoso , Estudos de Coortes , Feminino , Seguimentos , Hérnia Ventral/fisiopatologia , Humanos , Masculino , Pessoa de Meia-Idade , Procedimentos de Cirurgia Plástica/efeitos adversos , Recidiva , Estudos Retrospectivos , Medição de Risco , Índice de Gravidade de Doença , Retalhos Cirúrgicos/irrigação sanguínea , Telas Cirúrgicas , Deiscência da Ferida Operatória/diagnóstico , Resultado do Tratamento , Cicatrização/fisiologiaRESUMO
BACKGROUND: Abdominal pain attributed to compression of the celiac artery at the level of the median arcuate ligament (MAL) of the diaphragm is an uncommon disorder. Although ultrasound investigation and arteriography can be suggestive of the diagnosis, no definitive criteria exist with only cases reports in the literature. This study presents the only known reported case series in which a combination of open and laparoscopic access techniques of MAL decompression are reported. METHODS: A retrospective review of prospectively collected electronic databases of the University of North Carolina at Chapel Hill was performed for the period February 1999 until February 2009. Patients having undergone operation for celiac artery compression syndrome were identified and participated in a telephone interview. Questions were asked about the success of the operation, the recovery period, and patient satisfaction. RESULTS: Six patients were identified, 3 were male; mean age was 37.7 years. Four underwent open MAL division and celiac ganglion neurolysis, and 2 underwent a laparoscopic approach. Mean follow-up was 48.6 months. All patients experienced symptomatic improvement and were satisfied with their outcome. No patient had symptoms recurrence. CONCLUSION: In this limited experience, MAL division with celiac ganglion neurolysis appears to be an effective treatment for celiac artery compression syndrome in appropriately selected patients. Both the open and laparoscopic approaches are safe with durable midterm follow-up results.
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Arteriopatias Oclusivas/cirurgia , Artéria Celíaca , Descompressão Cirúrgica , Laparoscopia , Adulto , Arteriopatias Oclusivas/etiologia , Arteriopatias Oclusivas/patologia , Dissecação , Feminino , Humanos , Ligamentos/patologia , Ligamentos/cirurgia , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Resultado do Tratamento , Adulto JovemRESUMO
BACKGROUND: The rise in bariatric surgery has driven an increased number of complications from venous thromboembolism (VTE). Evidence supports obesity as an independent risk factor for VTE, but the specific derangements underlying the hypercoagulability of obesity are not well defined. To better characterize VTE risk for the purpose of tailoring prophylactic strategies, we developed a protocol for thrombophilia screening in patients presenting for bariatric surgery at our institution. METHODS: Between April 2004 and April 2006, 180 bariatric surgery candidates underwent serologic screening for inherited thrombophilias (Factor V-Leiden mutation, low Protein C activity, low Protein S activity, Free Protein S deficiency) and acquired thrombophilias (D-Dimer elevation, Fibrinogen elevation, elevation of coagulation factors VIII, IX, and XI, elevation of Lupus anticoagulants and homocysteine level, and Antithrombin III deficiency). Prevalence rate of each thrombophilia in the subject group was compared to the actual prevalence rate of the general population. RESULTS: Most plasma markers of both inherited and acquired thrombophilias were identified in higher than expected proportions, including D-Dimer elevation in 31%, Fibrinogen elevation in 40%, Factor VIII elevation in 50%, Factor IX elevation in 64%, Factor XI elevation in 50%, and Lupus anticoagulant in 13%. CONCLUSIONS: Obesity is a well-described demographic risk factor for VTE. In bariatric surgery candidates routinely screened for serologic markers, both inherited and acquired thrombophilias occurred more frequently than in the general population, and may therefore prove to be useful for individualized VTE risk assessment and prophylaxis.
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Cirurgia Bariátrica , Obesidade/complicações , Trombofilia/epidemiologia , Adulto , Idoso , Cirurgia Bariátrica/efeitos adversos , Índice de Massa Corporal , Estudos de Coortes , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Obesidade/cirurgia , Prevalência , Estudos Retrospectivos , Fatores de Risco , Trombofilia/diagnóstico , Tromboembolia Venosa/etiologia , Adulto JovemRESUMO
BACKGROUND: Despite a growing body of evidence guiding appropriate perioperative thromboprophylaxis in the general population, few data direct strategies to reduce deep venous thrombosis (DVT) and pulmonary embolism (PE) in the morbidly obese. We have implemented a novel protocol for venous thromboembolism (VTE) risk stratification in Roux-en-Y gastric bypass (RYGB) candidates at our institution, which augments clinical assessment with screening for thrombophilias, to guide retrievable inferior vena cava (IVC) filter utilization. METHODS: A retrospective review of prospectively collected data from patients who underwent primary RYGB between 2001 and 2008 at the University of North Carolina at Chapel Hill was completed. During that time, clinical assessment of VTE risk was amplified by focused plasma screening for common thrombophilias (factors VIII, IX, and XI, d-dimer, fibrinogen). Preoperative prophylactic IVC filters were offered to high-risk patients. The database was reviewed for perioperative DVTs, PEs, and filter-related complications. RESULTS: Of 330 patients, in 162 attempts, 160 had prophylactic IVC filters placed with four complications overall (2.47%). No patient had symptoms of PE during the planned 6-week filter period, though one had a PE occur immediately after filter removal (0.63%); in contrast, five of 170 patients (2.94%) without prophylactic IVC filters presented with symptomatic PE (p = 0.216). In total, 147 (91.88%) prophylactic filters were removed. CONCLUSIONS: Risk-group targeted prophylactic inferior vena cava filter placement prior to RYGB is safe with a trend towards reduced occurrence of PE.
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Derivação Gástrica , Complicações Pós-Operatórias/prevenção & controle , Filtros de Veia Cava , Tromboembolia Venosa/prevenção & controle , Feminino , Humanos , Masculino , Cuidados Pré-Operatórios , Embolia Pulmonar/prevenção & controle , Estudos Retrospectivos , Medição de RiscoRESUMO
BACKGROUND: Approximately one-third of U.S. adults are obese. Current evidence suggests that surgical therapies offer the morbidly obese the best hope for substantial and sustainable weight loss, with a resultant reduction in morbidity and mortality. Minimally invasive methods have altered the demand for bariatric procedures. However, no evidence-based clinical reviews yet exist to guide patients and surgeons in selecting the bariatric operation most applicable to a given situation. METHODS: This evidenced-based review is presented in conjunction with a clinical practice guideline developed by the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES). References were reviewed by the authors and graded as to the level of evidence. Recommendations were developed and qualified by the level of supporting evidence available at the time of the associated SAGES guideline publication. The guideline also was reviewed and co-endorsed by the American Society for Metabolic and Bariatric Surgery. RESULTS: Bariatric surgery is the most effective treatment for severe obesity, producing durable weight loss, improvement of comorbid conditions, and longer life. Patient selection algorithms should favor individual risk-benefit considerations over traditional anthropometric and demographic limits. Bariatric care should be delivered within credentialed multidisciplinary systems. Roux-en-Y gastric bypass (RGB), adjustable gastric banding (AGB), and biliopancreatic diversion with duodenal switch (BPD + DS) are validated procedures that may be performed laparoscopically. Laparoscopic sleeve gastrectomy (LSG) also is a promising procedure. Comparative data find that procedures with more dramatic clinical benefits carry greater risks, and those offering greater safety and flexibility are associated with less reliable efficacy. CONCLUSIONS: Laparoscopic RGB, AGB, BPD + DS, and primary LSG have been proved effective. Currently, the choice of operation should be driven by patient and surgeon preferences, as well as by considerations regarding the relative importance placed on discrete outcomes.
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Cirurgia Bariátrica/métodos , Laparoscopia , Obesidade Mórbida/cirurgia , Adulto , Cirurgia Bariátrica/efeitos adversos , Medicina Baseada em Evidências , Humanos , Seleção de Pacientes , Cuidados Pré-Operatórios , Resultado do TratamentoRESUMO
The vertical sleeve gastrectomy is a bariatric procedure that was originally described as the initial step in the biliopancreatic diversion. It demonstrated effectiveness in weight loss as a single procedure, and the laparoscopic vertical sleeve gastrectomy, as a stand-alone procedure, is now the most commonly performed bariatric surgery worldwide. Due to its relative technical ease and long-term data that have established its durability in treating obesity and its related comorbid conditions, the sleeve gastrectomy has grown in popularity among patients and surgeons. While there are variations in the technical aspects of performing a laparoscopic sleeve gastrectomy, key steps must be undertaken to produce safe and effective outcomes. This article reviews the indications for bariatric surgery, patient selection, surgical technique and tips, perioperative care and complications after sleeve gastrectomy.
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Cirurgia Bariátrica/métodos , Gastrectomia/métodos , Laparoscopia/métodos , Obesidade Mórbida/cirurgia , Cirurgia Bariátrica/efeitos adversos , Feminino , Gastrectomia/efeitos adversos , Humanos , Laparoscopia/efeitos adversos , Masculino , Pessoa de Meia-Idade , Seleção de Pacientes , Assistência Perioperatória/métodos , Complicações Pós-Operatórias/epidemiologia , Resultado do Tratamento , Redução de PesoRESUMO
Bariatric surgery reduces mortality for Americans who meet candidacy criteria and have insurance coverage. Unfortunately, some medically suitable candidates are denied or delayed during insurance approval processes. The long-term impact of such care delays on survival is unknown. Using a prospectively maintained bariatric intake database, we identified consecutive applicants who were evaluated and medically cleared by our multidisciplinary care team and for whom insurance approval was requested. We compared survival in those who were initially approved by their insurance carriers (controls) and those who were initially denied coverage (subjects). Mortality was determined using the Social Security Death Index. Kaplan-Meier survival curves were plotted and the log-rank test for significance was applied. From August 2003 to December 2008, 463 patients (391 females, mean age 45 ± 10 years, mean body mass index 52.5 ± 9.4 kg/m(2)) were medically cleared for a bariatric procedure. Of these, 363 were approved by insurance on initial request, whereas 100 were denied. Given the study's intention to measure the aggregate impact of delays and denials, nine patients who later came to operation after appeal or coverage change were maintained in the subject cohort. During 0- to 113-month follow-up, six subjects (6%) died compared with seven controls (1.9%), corresponding to a statistically significant survival benefit for patients initially approved for bariatric surgery without delay or denial (P < 0.001). In conclusion, access to bariatric surgical care was impeded by insurance certification processes in 22 per cent of medically acceptable candidates. Processes that delay or restrict efficient access to bariatric surgery are associated with a 3-fold mortality increase.
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Cirurgia Bariátrica/mortalidade , Acessibilidade aos Serviços de Saúde , Cobertura do Seguro , Seguro Saúde , Obesidade/mortalidade , Adolescente , Adulto , Cirurgia Bariátrica/economia , Bases de Dados Factuais , Feminino , Humanos , Estimativa de Kaplan-Meier , Masculino , Pessoa de Meia-Idade , North Carolina , Obesidade/economia , Obesidade/cirurgia , Adulto JovemAssuntos
Procedimentos Cirúrgicos do Sistema Biliar , Laparoscopia , Doenças Biliares/cirurgia , Procedimentos Cirúrgicos do Sistema Biliar/métodos , Procedimentos Cirúrgicos do Sistema Biliar/normas , Colangiopancreatografia Retrógrada Endoscópica , Colecistectomia Laparoscópica/métodos , Colecistectomia Laparoscópica/normas , Coledocolitíase/cirurgia , Ducto Colédoco/cirurgia , Humanos , Laparoscopia/efeitos adversos , Laparoscopia/métodos , Laparoscopia/normas , Laparotomia , Cuidados Pós-Operatórios , Cuidados Pré-OperatóriosRESUMO
BACKGROUND: With the increasing use of simulation in surgical training there is an increasing need for low cost methods of objective assessment. METHODS: Hand-motion data (3 degrees of freedom) were acquired using microelectromechanical gyroscope tracking devices worn on both hands during an intracorporeal suture/knot-tying laparoscopic task performed by FLS-certified and non-FLS-certified surgeons. Each data sample was processed into a symbolic time series, and the Lempel-Ziv complexity metric was calculated for each hand for the whole task and the first 60 seconds of the task from the dominant hand. RESULTS: FLS-certified surgeons had more complex hand-motion patterns. This was statistically significant only for the dominant hand (P = .02) but was still statistically significant when calculated from the first 60 seconds of the task (P = .04) and therefore independent of the total time taken to complete the task. CONCLUSIONS: Hand-motion patterns were quantified and shown to be different between FLS-certified and non-FLS-certified surgeons using low-cost microelectromechanical technology and the Lempel-Ziv complexity metric.
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Certificação , Competência Clínica , Educação de Graduação em Medicina/métodos , Mãos/fisiologia , Laparoscopia/métodos , Médicos/legislação & jurisprudência , Desempenho Psicomotor/fisiologia , Instrução por Computador , Avaliação Educacional , Humanos , Técnicas de Sutura/educação , Análise e Desempenho de Tarefas , Fatores de TempoRESUMO
OBJECTIVE: Symptoms of both gastroesophageal reflux disease (GERD) and irritable bowel syndrome (IBS) are frequently reported by individuals who binge eat. Higher body mass index (BMI) has also been associated with these disorders and with binge eating (BE). However, it is unknown whether BE influences GERD/IBS and how BMI might affect these associations. Thus, we examined the potential associations among BE, GERD, IBS, and BMI. METHODS: Participants were from the Swedish Twin study of Adults: Genes and Environment (STAGE) and provided information on disordered eating behavior, BMI, gastrointestinal (GI) disorders, and commonly comorbid psychiatric and somatic illnesses. Key features of GERD and IBS were identified to create modified definitions of both disorders that were used as primary outcome variables. Logistic regression models were applied to determine the association between BE and each GERD/IBS both independently and in the context of BMI and other commonly comorbid psychiatric and somatic morbidities. RESULTS: Prevalence estimates for GERD and IBS were higher among women than men (all p-values<.001). Only the association between BE and IBS was significant in both men and women after adjustment for BMI and the psychiatric/somatic morbidities. CONCLUSION: BE appears to be an important consideration in the presence of IBS symptoms in both men and women, even when considering the impact of BMI and other commonly comorbid conditions. This association underscores the importance of routine assessment of BE in patients presenting with IBS to effectively manage the concurrent presentation of these problems.
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Índice de Massa Corporal , Bulimia , Refluxo Gastroesofágico/etiologia , Síndrome do Intestino Irritável/etiologia , Adulto , Comorbidade , Ingestão de Alimentos , Feminino , Refluxo Gastroesofágico/epidemiologia , Gastroenteropatias/epidemiologia , Gastroenteropatias/etiologia , Humanos , Síndrome do Intestino Irritável/epidemiologia , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , PrevalênciaRESUMO
Gastric fundus compliance allows stomach volume increase in response to food intake. Absence of this postprandial relaxation alters hormonal signals and induces early satiety and weight loss. This study demonstrates the effect of gastric fundus invagination on the growth rate of juvenile pigs. After institutional animal care and use committee approval, 15 juvenile pigs were divided into two groups. In the first group, six pigs were anesthetized, weighed, and submitted to laparotomy, stomach manipulation, and short gastric vessel ligation. This is the control group and is referred to as "Sham". In the second group, gastric fundus invagination was added by using a circular stapler. This is the procedure group and is designated as "GFI". Postoperatively, body weight and food intake were measured for 5 weeks. Pigs were euthanized and the stomachs examined. Growth patterns were compared. Three animals were excluded from the analysis. At the end of the 5-week study period, six GFI pigs had intact anastomosis with an invaginated fundus. The mean percent growth rate for the GFI group (54.2 ± 2.8 %) was significantly less than the Sham group (77.7 ± 4.9 %). Gastric fundus invagination significantly decreases the growth rate in juvenile pigs.
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Fundoplicatura/métodos , Fundo Gástrico/cirurgia , Obesidade/cirurgia , Redução de Peso , Animais , Peso Corporal , Modelos Animais de Doenças , Ingestão de Alimentos , Feminino , Distribuição Aleatória , Suínos/crescimento & desenvolvimentoRESUMO
Background. Bariatric surgery has increased across America. Venous access is difficult in these patients. Anesthesiologists often utilize valuable operating room (OR) time acquiring reliable intravenous lines. Our objective was to determine if outpatient central venous line (CVL) placement improves OR efficiency and professional reimbursement for CVL insertion. Methods. In our bariatric practice, selected surgery patients have outpatient CVLs placed during prophylactic vena cava filter placement. In a cohort of 268 gastric bypass patients operated between 1/01 and 11/06, we compared time-to-incision between 106 with pre-established CVLs and 162 without. In addition, we determined professional compensation rates for CVLs placed outpatient versus CVLs inserted in the OR. Results. Patients with preoperative (outpatient) CVLs required 35.6 ± 12.5 minutes to skin incision compared with 42.5 ± 13.9 minutes for controls (P < 0.0001), and 34.9% had skin incision in <30 minutes compared with 16.4% of controls. Radiologists collected 28.2% of outpatient billings for CPT code 36556, compared with anesthesiologists who collected <1% when placing CVLs in the OR. Conclusions. Outpatient CVLs prior to gastric bypass improve efficiency in the OR with earlier skin incision. Professional reimbursement is better for outpatient CVLs than intraoperative inpatient CVLs.
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BACKGROUND: Recent years have seen the establishment of bariatric surgery credentialing processes, center-of-excellence programs, and fellowship training positions. The effects of center-of-excellence status and of the presence of training programs have not previously been examined. The objective of this study was to examine the effects of case volume, center-of-excellence status, and training programs on early outcomes of bariatric surgery. STUDY DESIGN: Data were obtained from the Nationwide Inpatient Sample from 1998 to 2006. Quantification of patient comorbidities was made using the Charlson Index. Using logistic regression modeling, annual case volumes were analyzed for an association with each institution's center-of-excellence status and training program status. Risk-adjusted outcomes measures were calculated for these hospital-level parameters. RESULTS: Data from 102,069 bariatric operations were obtained. Adjusting for comorbidities, greater bariatric case volume was associated with improvements in the incidence of total complications (odds ratio [OR] 0.99937 for each single case increase, p = 0.01), in-hospital mortality (OR 0.99717, p < 0.01), and most other complications. Hospitals with a Fellowship Council-affiliated gastrointestinal surgery training program were associated with risk-adjusted improvements in rates of splenectomy (OR 0.2853, p < 0.001) and bacterial pneumonias (OR 0.65898, p = 0.02). Center-of-excellence status, irrespective of the accrediting entity, had minimal independent association with outcomes. A surgical residency program had a varying association with outcomes. CONCLUSIONS: The hypothesized positive volume-outcomes relationship of bariatric surgery is shown without arbitrarily categorizing hospitals to case volume groups, by analysis of volume as a continuous variable. Institutions with a dedicated fellowship training program have also been shown, in part, to be associated with improved outcomes. The concept of volume-dependent center-of-excellence programs is supported, although no independent association with the credentialing process is noted.
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Cirurgia Bariátrica/normas , Bolsas de Estudo , Obesidade Mórbida/cirurgia , Avaliação de Resultados em Cuidados de Saúde , Carga de Trabalho , Cirurgia Bariátrica/educação , Cirurgia Bariátrica/mortalidade , Credenciamento , Educação de Pós-Graduação em Medicina/normas , Mortalidade Hospitalar , Humanos , Modelos Logísticos , Complicações Pós-Operatórias/epidemiologia , Estados Unidos/epidemiologiaRESUMO
BACKGROUND: Reports of increasing bariatric surgery volumes have driven resource allocation by health care systems and device manufacturers. Professional organizations and third-party payers have embraced credentialing systems to limit frivolous expansion. The underlying data upon which these reports are based are disparate and derived from imperfect methodologies. We queried the Nationwide Inpatient Sample (NIS) using several established search strategies to validate the current understanding of bariatric trends. METHODS: NIS search algorithms capture bariatric admissions by the presence of International Classification of Disease, Ninth-Revision, Clinical Modification (ICD-9-CM) codes for obesity and bariatric procedures, with varying levels of inclusiveness for related foregut procedure codes. We applied 1 novel and 4 established algorithms to NIS data sets from 1998 to 2006 to generate contemporary case-volume curves, and we supplemented our data with industry estimates of ambulatory surgery volumes. RESULTS: From 1998 to 2003, the number of bariatric operations increased markedly by all search strategies. Since then, a greater variation was observed in case volume estimates but no evidence of continuing growth was identified, irrespective of the search protocol employed. CONCLUSION: Bariatric procedures peaked in 2003 and have since plateaued. The estimation of case volumes is limited by deficiencies in data and nonuniform search criteria. These factors should be considered by surgeons, professional organizations, hospitals, and third-party payers when planning for the future.
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Cirurgia Bariátrica/tendências , Cirurgia Bariátrica/estatística & dados numéricos , Humanos , Estados UnidosRESUMO
BACKGROUND: Biliary surgery can often be very complex, with difficult access issues, small structures to be manipulated and sutured and proximity to major vessels. Additionally, biliary surgery is often reoperative. All of these issues have the potential to be aided by the use of technology which provides three-dimensional (3D) vision, excellent illumination and access, with steady instrument control under maximal magnification. The robot is such a technology which is currently available. METHODS: The Da Vinci robot was used to perform a robotic choledochojejunostomy, using five ports and a totally intracorporeal technique. RESULTS: Two patients were studied. There were no conversions to open operation. There was no mortality. One patient experienced a postoperative bile leak, which was successfully managed endoscopically. CONCLUSIONS: Robotic choledochojejunostomy with intracorporeal Roux-en-Y anastomosis is a feasible operation with a definite learning curve. It has potential benefits to the patient.