Detalhe da pesquisa
1.
Machine Learning-Boosted Docking Enables the Efficient Structure-Based Virtual Screening of Giga-Scale Enumerated Chemical Libraries.
J Chem Inf Model
; 63(18): 5773-5783, 2023 09 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37655823
2.
Design, synthesis and biological evaluation of antiparasitic dinitroaniline-ether phospholipid hybrids.
Bioorg Chem
; 138: 106615, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37244229
3.
SARS-CoV-2-host proteome interactions for antiviral drug discovery.
Mol Syst Biol
; 17(11): e10396, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34709727
4.
Global profiling of SRP interaction with nascent polypeptides.
Nature
; 536(7615): 219-23, 2016 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27487212
5.
The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing.
PLoS Pathog
; 14(9): e1007315, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30252911
6.
Comparative mapping of on-targets and off-targets for the discovery of anti-trypanosomatid folate pathway inhibitors.
Biochim Biophys Acta Gen Subj
; 1861(12): 3215-3230, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28939533
7.
Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity.
Molecules
; 22(3)2017 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28282886
8.
Drug repurposing platform for deciphering the druggable SARS-CoV-2 interactome.
Antiviral Res
; 223: 105813, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38272320
9.
MatchTope: A tool to predict the cross reactivity of peptides complexed with Major Histocompatibility Complex I.
Front Immunol
; 13: 930590, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36389840
10.
Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1.
J Med Chem
; 65(13): 9011-9033, 2022 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35675511
11.
Virus structure and structure-based antivirals.
Curr Opin Virol
; 51: 16-24, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34564030
12.
Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections.
J Med Chem
; 62(8): 3989-4012, 2019 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30908048
13.
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform.
SLAS Discov
; 24(3): 346-361, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30784368
14.
Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery.
ACS Omega
; 2(9): 5666-5683, 2017 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28983525