Detalhe da pesquisa
1.
Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype.
Genes Dev
; 38(5-6): 273-288, 2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38589034
2.
WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma.
Genes Dev
; 37(3-4): 86-102, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36732025
3.
Functional dissection of human mitotic genes using CRISPR-Cas9 tiling screens.
Genes Dev
; 36(7-8): 495-510, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35483740
4.
Both YAP1-MAML2 and constitutively active YAP1 drive the formation of tumors that resemble NF2 mutant meningiomas in mice.
Genes Dev
; 2022 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36008139
5.
Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3.
Cell
; 153(2): 335-47, 2013 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-23582324
6.
Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis.
Genes Dev
; 34(15-16): 1051-1064, 2020 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32675324
7.
A modular CRISPR screen identifies individual and combination pathways contributing to HIV-1 latency.
PLoS Pathog
; 19(1): e1011101, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36706161
8.
Hyper-active RAS/MAPK introduces cancer-specific mitotic vulnerabilities.
Proc Natl Acad Sci U S A
; 119(41): e2208255119, 2022 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36191188
9.
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma.
Nature
; 547(7663): 355-359, 2017 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28678782
10.
Neural G0: a quiescent-like state found in neuroepithelial-derived cells and glioma.
Mol Syst Biol
; 17(6): e9522, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34101353
11.
BuGZ facilitates loading of spindle assembly checkpoint proteins to kinetochores in early mitosis.
J Biol Chem
; 295(43): 14666-14677, 2020 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32820050
12.
Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism.
Proc Natl Acad Sci U S A
; 115(21): 5462-5467, 2018 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29735700
13.
Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A.
Genes Dev
; 27(9): 1032-45, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23651857
14.
Screen for reactivation of MeCP2 on the inactive X chromosome identifies the BMP/TGF-ß superfamily as a regulator of XIST expression.
Proc Natl Acad Sci U S A
; 114(7): 1619-1624, 2017 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28143937
15.
G9a/GLP-dependent histone H3K9me2 patterning during human hematopoietic stem cell lineage commitment.
Genes Dev
; 26(22): 2499-511, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23105005
16.
Comparison of glioblastoma (GBM) molecular classification methods.
Semin Cancer Biol
; 53: 201-211, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30031763
17.
Second-generation shRNA libraries covering the mouse and human genomes.
Nat Genet
; 37(11): 1281-8, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16200065
18.
FBXO42 activity is required to prevent mitotic arrest, spindle assembly checkpoint activation and lethality in glioblastoma and other cancers.
NAR Cancer
; 6(2): zcae021, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38774470
19.
Breaking out of the cycle: Including quiescence in cell cycle classification.
bioRxiv
; 2024 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38659838
20.
Integrative network analysis of signaling in human CD34(+) hematopoietic progenitor cells by global phosphoproteomic profiling using TiO2 enrichment combined with 2D LC-MS/MS and pathway mapping.
Proteomics
; 13(8): 1325-33, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23401153