Analysis of Sleep Macrostructure in Patients Diagnosed with Parkinson's Disease.

Patients diagnosed with Parkinson's disease present sleep disorders with a higher frequency than the general population. The sleep architecture in these patients shows variations with respect to the normal population, so in this work it was decided to investigate the characteristics of the macroarchitecture of sleep in patients diagnosed with Parkinson's disease. A polysomnographic study was carried out on 77 patients diagnosed with Parkinson's disease. All the studies were processed according to the AASM Manual for the Scoring of Sleep and Associated Events v.2.2, and to the criteria of the International Classification of Sleep Disorders 3rd ed. (2014). Processing was carried out using descriptive statistics, as well as non-parametric analysis for comparison between cases and controls. The group of patients showed significant reductions of the N2, N3, and REM sleep stages when compared with a control group, as well as a significant increase in intra-sleep wakefulness. The number of REM⁻NoREM sleep cycles and sleep efficiency showed marked reduction compared to the control group. There was a statistically significant difference in the macroarchitecture of sleep between patients diagnosed with Parkinson's disease and healthy controls.

Abordaje integral en el tratamiento de la enfermedad de Parkinson / Integral approach in Parkinson disease treatment

La Enfermedad de Parkinson Idiopática(EPI) es una afección crónica no trasmisible del Sistema Nervioso Central, de causa degenerativa. La EPI es una de las enfermedades crónicas con mas impacto obre la forma de vida del paciente, pues despúes de su diagnóstico, la mayoría de los casos sobreviven muchos años. Como un tratamiento causal aún no es posible, el objetivo médico es elevar la calidad de vida y lograr el máximo de independencia. Esta es la razón por la que, actualmente la atención se dirige cada vez más hacia un tratamiento multidisciplinario de la enfermedad. El impacto para el individuo y sus familiares frente a este diagnóstico es importante, pues se trata de una enfermedad sin cura, progresiva y con un futuro impredecible. Por tanto, una buena relación médico paciente, además de un adecuado nivel de información, son imprescindibles para su oportuno manejo