Detalhe da pesquisa
1.
Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections.
Proc Natl Acad Sci U S A
; 119(22): e2122506119, 2022 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35622893
2.
Discovery and characterization of bromodomain 2-specific inhibitors of BRDT.
Proc Natl Acad Sci U S A
; 118(9)2021 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33637650
3.
DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 Mpro inhibitors.
Proc Natl Acad Sci U S A
; 118(36)2021 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34426525
4.
Pharmacological Characterization of Low Molecular Weight Biased Agonists at the Follicle Stimulating Hormone Receptor.
Int J Mol Sci
; 22(18)2021 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34576014
5.
Reversible male contraception by targeted inhibition of serine/threonine kinase 33.
Science
; 384(6698): 885-890, 2024 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38781365
6.
Discovery of Highly Potent and BMPR2-Selective Kinase Inhibitors Using DNA-Encoded Chemical Library Screening.
J Med Chem
; 66(3): 2143-2160, 2023 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36719862
7.
Follicle-Stimulating Hormone Induces Lipid Droplets via Gαi/o and ß-Arrestin in an Endometrial Cancer Cell Line.
Front Endocrinol (Lausanne)
; 12: 798866, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35185785
8.
A long-acting tumor necrosis factor alpha-binding protein demonstrates activity in both in vitro and in vivo models of endometriosis.
J Pharmacol Exp Ther
; 334(2): 460-6, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20435921
9.
Tumor necrosis factor-alpha regulates inflammatory and mesenchymal responses via mitogen-activated protein kinase kinase, p38, and nuclear factor kappaB in human endometriotic epithelial cells.
Mol Pharmacol
; 73(5): 1394-404, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18252806
10.
Pharmacological and functional characterization of novel EP and DP receptor agonists: DP1 receptor mediates penile erection in multiple species.
J Sex Med
; 5(2): 344-56, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18047485
11.
Bentamapimod (JNK Inhibitor AS602801) Induces Regression of Endometriotic Lesions in Animal Models.
Reprod Sci
; 23(1): 11-23, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26335175
12.
c-Jun NH2-terminal kinase inhibitor bentamapimod reduces induced endometriosis in baboons: an assessor-blind placebo-controlled randomized study.
Fertil Steril
; 105(3): 815-824.e5, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26654972
13.
Discovery and Development of Small Molecule Allosteric Modulators of Glycoprotein Hormone Receptors.
Front Endocrinol (Lausanne)
; 6: 142, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26441832
14.
Relaxin increases secretion of tissue inhibitor of matrix metalloproteinase-1 and -2 during uterine and cervical growth and remodeling in the pig.
Endocrinology
; 143(1): 91-8, 2002 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-11751597
15.
Biomarkers in reproductive medicine: the promise, and can it be fulfilled?
Fertil Steril
; 99(4): 954-62, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23246448
16.
Discovery of new molecules for future treatment of infertility.
Reprod Biomed Online
; 10 Suppl 3: 45-54, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23577415
17.
Follicle-stimulating hormone activates extracellular signal-regulated kinase but not extracellular signal-regulated kinase kinase through a 100-kDa phosphotyrosine phosphatase.
J Biol Chem
; 278(9): 7167-79, 2003 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-12493768