Detalhe da pesquisa
1.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature
; 569(7757): 503-508, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31068700
2.
Phosphorylation Regulates Id2 Degradation and Mediates the Proliferation of Neural Precursor Cells.
Stem Cells
; 34(5): 1321-31, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26756672
3.
Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal.
Genome Biol
; 24(1): 192, 2023 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37612728
4.
p53 directly represses Id2 to inhibit the proliferation of neural progenitor cells.
Stem Cells
; 29(7): 1090-101, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21608079
5.
Systematic profiling of conditional degron tag technologies for target validation studies.
Nat Commun
; 13(1): 5495, 2022 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36127368
6.
Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer.
Nat Cancer
; 3(6): 681-695, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35437317
7.
Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.
Nat Genet
; 53(12): 1664-1672, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34857952
8.
Selective Modulation of a Pan-Essential Protein as a Therapeutic Strategy in Cancer.
Cancer Discov
; 11(9): 2282-2299, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33883167
9.
A first-generation pediatric cancer dependency map.
Nat Genet
; 53(4): 529-538, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33753930
10.
Targeting Cancer Gene Dependencies with Anthrax-Mediated Delivery of Peptide Nucleic Acids.
ACS Chem Biol
; 15(6): 1358-1369, 2020 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32348107
11.
Loss of heterozygosity of essential genes represents a widespread class of potential cancer vulnerabilities.
Nat Commun
; 11(1): 2517, 2020 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32433464
12.
Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action.
Nat Commun
; 11(1): 4296, 2020 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32855387
13.
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.
Cell Rep
; 33(11): 108493, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33326793
14.
Id2 is required for specification of dopaminergic neurons during adult olfactory neurogenesis.
J Neurosci
; 28(52): 14074-86, 2008 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19109490
15.
Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells.
Nat Commun
; 10(1): 3731, 2019 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31427603
16.
Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma.
Nat Commun
; 10(1): 2400, 2019 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31160565
17.
Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability.
Elife
; 62017 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28177281
18.
Gliomas "Dope Up" for Growth.
Cancer Cell
; 29(6): 778-780, 2016 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27300432
19.
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.
Cell Rep
; 36(2): 109367, 2021 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34260938
20.
MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism.
Nat Genet
; 48(3): 273-82, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26829751