LiDAR-Based Snowfall Level Classification for Safe Autonomous Driving in Terrestrial, Maritime, and Aerial Environments.

Studies on autonomous driving have started to focus on snowy environments, and studies to acquire data and remove noise and pixels caused by snowfall in such environments are in progress. However, research to determine the necessary weather information for the control of unmanned platforms by sensing the degree of snowfall in real time has not yet been conducted. Therefore, in this study, we attempted to determine snowfall information for autonomous driving control in snowy weather conditions. To this end, snowfall data were acquired by LiDAR sensors in various snowy areas in South Korea, Sweden, and Denmark. Snow, which was extracted using a snow removal filter (the LIOR filter that we previously developed), was newly classified and defined based on the extracted number of snow particles, the actual snowfall total, and the weather forecast at the time. Finally, we developed an algorithm that extracts only snow in real time and then provides snowfall information to an autonomous driving system. This algorithm is expected to have a similar effect to that of actual controllers in promoting driving safety in real-time weather conditions.

Inhibition of human mesenchymal stem cell proliferation via Wnt signaling activation.

Human mesenchymal stem cells (hMSCs), characterized by rapid in vitro expandability and multi-differentiation potential, have been widely used in the clinical field of tissue engineering. Recent studies have shown that various signaling networks are involved in the growth and differentiation of hMSCs. Although Wnts and their downstream signaling components have been implicated in the regulation of hMSCs, the role of Wnt signaling in hMSC self-renewal is still controversial. Here, it was observed that activation of endogenous canonical Wnt signaling with LiCl, which decreased ß-catenin phosphorylation, leads to a decrease in hMSC proliferation. The fact that this growth arrest is not linked to apoptosis was verified by annexin V-FITC/propidium iodide assay. It was associated with sealing off of the cells in the G1 phase of the cell cycle accompanied by changes in expression of cell cycle-associated genes such as cyclin A and D. In addition, activation of Wnt signaling during hMSC proliferation seemed to reduce their clonogenic potential. On the contrary, Wnt signaling activation during hMSC proliferation had little effect on the osteogenic differentiation capability of cells. These findings show that canonical Wnt signaling is a critical regulator of hMSC proliferation and clonogenicity.

A compact series elastic element using a rubber compression mechanism.

This paper presents the concept of a new rubber compression mechanism for rotary compact series elastic elements, which can be used in robotic joints in human-machine interaction devices. A compact elastic element is realized using rubber materials with a higher specific energy and energy density than steel or fiberglass, which are commonly used in commercial springs. To overcome the nonlinearity and hysteresis of the proposed compression mechanism, a mathematical Bouc-Wen model developed through parameter identification is proposed. This paper describes the working principle of the new elastic element and presents the modeling method. Experiments on the Bouc-Wen model conducted to demonstrate the suggested mechanism are reported, and the results show that the proposed elastic element can be used for robotic joints in human-machine interaction devices.

Diagnostic accuracy and reliability of panoramic temporomandibular joint (TMJ) radiography to detect bony lesions in patients with TMJ osteoarthritis.

BACKGROUND/PURPOSE: The value of the temporomandibular joint (TMJ) projections of panoramic radiography for diagnosing TMJ osteoarthritis is not completely elucidated. This study aimed to assess the diagnostic accuracy and reliability of panoramic TMJ radiography to detect bony lesions in patients with TMJ osteoarthritis. MATERIALS AND METHODS: This study included 55 TMJs of 44 subjects who were diagnosed with TMJ osteoarthritis. They underwent panoramic radiography (PanRad), lateral (LatTMJ) and frontal (FrnTMJ) projection panoramic TMJ radiography, and cone-beam computed tomography (CBCT). All images were examined by two observers for flattening, erosion, and osteophytes on the condylar head and articular eminence of the TMJ. RESULTS: For detecting flattening lesions on the mandibular condyle, the sensitivities of PanRad, LatTMJ, and FrnTMJ were less than 67% and the combination of LatTMJ and FrnTMJ (ComTMJ) had the highest sensitivity for both observers (67.6% and 79.7%, respectively). For erosion lesions, the sensitivity of ComTMJ for observer 1 was the highest, at 84.3%, whereas the specificity of ComTMJ was the lowest, at 37.5%. The sensitivities of all four methods for observer 2 were less than 54% and the specificities ranged from 75.0% to 100%. The overall diagnostic accuracy was highest for ComTMJ (64.3%), followed by LatTMJ (59.5%). The intraobserver reliability was good for one observer and excellent for the other, and the interobserver reliability was fair or moderate. CONCLUSION: Panoramic TMJ radiography demonstrated limited diagnostic accuracy and acceptable reliability in detecting bony lesions of the TMJ, although it was better than conventional panoramic radiography.

Repeatability of measurements of surface electromyographic variables during maximum voluntary contraction of temporalis and masseter muscles in normal adults.

This study evaluated the intraexaminer repeatability of measurements of surface electromyography (EMG) variables and functional indices of the myoelectric signals from the masseter and temporalis muscles bilaterally in 15 healthy men. The test was repeated on two different days without templates. The resting muscle activity was recorded once, and two kinds of maximum voluntary contraction (MVC) tasks were performed and recorded three times. The two MVC tasks involved clenching the teeth and biting down on two cotton rolls bilaterally with the posterior teeth. The intraclass correlation coefficient (ICC) of amplitude was >88% and that of frequency was >95% during the two MVC tasks but not under resting conditions. The ICC of the asymmetry and activity indices during the two MVC tasks was >76%. A Bland-Altman analysis revealed no significant difference in amplitude or frequency or in the two indices between the two days during the MVC tasks. In conclusion, the measurements of surface EMG variables and the indices obtained according to the study protocol were highly repeatable in healthy men. Additional studies using templates and intraexaminer measurement errors are warranted in both men and women for complete validation of these findings.