Detalhe da pesquisa
1.
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer.
Nature
; 547(7662): 222-226, 2017 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28678784
2.
Cell cycle status of CD34(+) hemopoietic stem cells determines lentiviral integration in actively transcribed and development-related genes.
Mol Ther
; 23(4): 683-96, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25523760
3.
The fetal mouse is a sensitive genotoxicity model that exposes lentiviral-associated mutagenesis resulting in liver oncogenesis.
Mol Ther
; 21(2): 324-37, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23299800
4.
Targeted resequencing for analysis of clonal composition of recurrent gene mutations in chronic lymphocytic leukaemia.
Br J Haematol
; 163(4): 496-500, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24032483
5.
Lentiviral vector integration profiles differ in rodent postmitotic tissues.
Mol Ther
; 19(4): 703-10, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21364536
6.
Retroviral gene therapy for X-linked chronic granulomatous disease: results from phase I/II trial.
Mol Ther
; 19(11): 2092-101, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21878903
7.
Insertion sites in engrafted cells cluster within a limited repertoire of genomic areas after gammaretroviral vector gene therapy.
Mol Ther
; 19(11): 2031-9, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21862999
8.
The balance between the intronic miR-342 and its host gene Evl determines hematopoietic cell fate decision.
Leukemia
; 35(10): 2948-2963, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34021250
9.
Mapping Active Gene-Regulatory Regions in Human Repopulating Long-Term HSCs.
Cell Stem Cell
; 23(1): 132-146.e9, 2018 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29979988
10.
High-resolution analysis of the human T-cell receptor repertoire.
Nat Commun
; 6: 8081, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26324409
11.
High-throughput monitoring of integration site clonality in preclinical and clinical gene therapy studies.
Mol Ther Methods Clin Dev
; 2: 14061, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26052530
12.
Successful Combination of Sequential Gene Therapy and Rescue Allo-HSCT in Two Children with X-CGD - Importance of Timing.
Curr Gene Ther
; 15(4): 416-27, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25981636
13.
Gene therapy for Wiskott-Aldrich Syndrome-Long-term reconstitution and clinical benefits, but increased risk for leukemogenesis.
Rare Dis
; 2(1): e947749, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-26942098
14.
Gene therapy for Wiskott-Aldrich syndrome--long-term efficacy and genotoxicity.
Sci Transl Med
; 6(227): 227ra33, 2014 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24622513
15.
Next-generation sequencing of cancer consensus genes in lymphoma.
Leuk Lymphoma
; 54(8): 1831-5, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23621802
16.
Analysis of the clonal repertoire of gene-corrected cells in gene therapy.
Methods Enzymol
; 507: 59-87, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22365769
17.
Bioinformatic clonality analysis of next-generation sequencing-derived viral vector integration sites.
Hum Gene Ther Methods
; 23(2): 111-8, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22559057
18.
Genome-wide high-throughput integrome analyses by nrLAM-PCR and next-generation sequencing.
Nat Protoc
; 5(8): 1379-95, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20671722
19.
Comprehensive genomic access to vector integration in clinical gene therapy.
Nat Med
; 15(12): 1431-6, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19966782