Detalhe da pesquisa
1.
Interrogation of the Atherosclerosis-Associated SORT1 (Sortilin 1) Locus With Primary Human Hepatocytes, Induced Pluripotent Stem Cell-Hepatocytes, and Locus-Humanized Mice.
Arterioscler Thromb Vasc Biol
; 38(1): 76-82, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29097363
2.
Functional analysis and transcriptomic profiling of iPSC-derived macrophages and their application in modeling Mendelian disease.
Circ Res
; 117(1): 17-28, 2015 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25904599
3.
Distinct enhancers of ptf1a mediate specification and expansion of ventral pancreas in zebrafish.
Dev Biol
; 381(2): 471-81, 2013 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23876428
4.
Evaluating the Contribution of Cell Type-Specific Alternative Splicing to Variation in Lipid Levels.
Circ Genom Precis Med
; 16(3): 248-257, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37165871
5.
GDF15 neutralization restores muscle function and physical performance in a mouse model of cancer cachexia.
Cell Rep
; 42(1): 111947, 2023 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36640326
6.
Chronic UCN2 treatment desensitizes CRHR2 and improves insulin sensitivity.
Nat Commun
; 14(1): 3953, 2023 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37402735
7.
BDK inhibition acts as a catabolic switch to mimic fasting and improve metabolism in mice.
Mol Metab
; 66: 101611, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36220546
8.
ACE inhibition and cardiometabolic risk factors, lung ACE2 and TMPRSS2 gene expression, and plasma ACE2 levels: a Mendelian randomization study.
R Soc Open Sci
; 7(11): 200958, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-33391794
9.
Evaluation of cis-regulatory function in zebrafish.
Brief Funct Genomic Proteomic
; 7(6): 465-73, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18820318
10.
Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress.
Cell Rep
; 19(7): 1456-1466, 2017 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28514664
11.
ATP-Binding Cassette Transporter A1 Deficiency in Human Induced Pluripotent Stem Cell-Derived Hepatocytes Abrogates HDL Biogenesis and Enhances Triglyceride Secretion.
EBioMedicine
; 18: 139-145, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28330813
12.
A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia.
Cell Stem Cell
; 20(4): 478-489.e5, 2017 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28388428
13.
Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci.
Cell Stem Cell
; 20(4): 558-570.e10, 2017 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28388432
14.
Pluripotency redux--advances in stem-cell research.
N Engl J Med
; 357(15): 1469-72, 2007 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-17928593