Detalhe da pesquisa
1.
TDP-43 condensation properties specify its RNA-binding and regulatory repertoire.
Cell
; 184(18): 4680-4696.e22, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34380047
2.
MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration.
Nature
; 594(7861): 117-123, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34012113
3.
A Liquid to Solid Phase Transition Underlying Pathological Huntingtin Exon1 Aggregation.
Mol Cell
; 70(4): 588-601.e6, 2018 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29754822
4.
Meta-analysis of human and mouse ALS astrocytes reveals multi-omic signatures of inflammatory reactive states.
Genome Res
; 32(1): 71-84, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34963663
5.
Physiological intron retaining transcripts in the cytoplasm abound during human motor neurogenesis.
Genome Res
; 32(10): 1808-1825, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36180233
6.
Elevated 4R tau contributes to endolysosomal dysfunction and neurodegeneration in VCP-related frontotemporal dementia.
Brain
; 147(3): 970-979, 2024 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37882537
7.
APP antisense oligonucleotides reduce Aß aggregation and rescue endolysosomal dysfunction in Alzheimer's disease.
Brain
; 2024 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38527856
8.
Direct m6A recognition by IMP1 underlays an alternative model of target selection for non-canonical methyl-readers.
Nucleic Acids Res
; 51(16): 8774-8786, 2023 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37377445
9.
Molecular mechanisms of amyotrophic lateral sclerosis as broad therapeutic targets for gene therapy applications utilizing adeno-associated viral vectors.
Med Res Rev
; 43(4): 829-854, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36786126
10.
The FUS gene is dual-coding with both proteins contributing to FUS-mediated toxicity.
EMBO Rep
; 22(1): e50640, 2021 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33226175
11.
The role of astrocytes in prion-like mechanisms of neurodegeneration.
Brain
; 145(1): 17-26, 2022 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35265969
12.
Astrocytes display cell autonomous and diverse early reactive states in familial amyotrophic lateral sclerosis.
Brain
; 145(2): 481-489, 2022 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35042241
13.
Reactive astrocytes in ALS display diminished intron retention.
Nucleic Acids Res
; 49(6): 3168-3184, 2021 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33684213
14.
Elevated 4R-tau in astrocytes from asymptomatic carriers of the MAPT 10+16 intronic mutation.
J Cell Mol Med
; 26(4): 1327-1331, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34951131
15.
Image-based deep learning reveals the responses of human motor neurons to stress and VCP-related ALS.
Neuropathol Appl Neurobiol
; 48(2): e12770, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34595747
16.
Aberrant cytoplasmic intron retention is a blueprint for RNA binding protein mislocalization in VCP-related amyotrophic lateral sclerosis.
Brain
; 144(7): 1985-1993, 2021 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33693641
17.
Regionally encoded functional heterogeneity of astrocytes in health and disease: A perspective.
Glia
; 69(1): 20-27, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32749770
18.
The microglial component of amyotrophic lateral sclerosis.
Brain
; 143(12): 3526-3539, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33427296
19.
Decoding the relationship between ageing and amyotrophic lateral sclerosis: a cellular perspective.
Brain
; 143(4): 1057-1072, 2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31851317
20.
Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis.
Brain
; 143(2): 430-440, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32040555