Detalhe da pesquisa
1.
Synthon-based ligand discovery in virtual libraries of over 11 billion compounds.
Nature
; 601(7893): 452-459, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34912117
2.
XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity.
Nature
; 569(7755): 289-292, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31019305
3.
Structural basis of ligand recognition at the human MT1 melatonin receptor.
Nature
; 569(7755): 284-288, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31019306
4.
Publisher Correction: Structural basis of ligand recognition at the human MT1 melatonin receptor.
Nature
; 569(7756): E6, 2019 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-31048811
5.
Structural basis for selectivity and diversity in angiotensin II receptors.
Nature
; 544(7650): 327-332, 2017 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28379944
6.
Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody.
Proc Natl Acad Sci U S A
; 114(31): 8223-8228, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28716900
7.
Extrinsic Tryptophans as NMR Probes of Allosteric Coupling in Membrane Proteins: Application to the A2A Adenosine Receptor.
J Am Chem Soc
; 140(26): 8228-8235, 2018 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29874058
8.
Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor.
J Biol Chem
; 290(49): 29127-39, 2015 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26420482
9.
Structure-based discovery of potent and selective melatonin receptor agonists.
Elife
; 92020 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32118583
10.
Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists.
Sci Adv
; 5(11): eaax9115, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31807708
11.
Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs.
Sci Adv
; 5(10): eaax2518, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31633023
12.
Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors.
Nat Commun
; 10(1): 5573, 2019 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31811124
13.
Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling.
Structure
; 26(2): 259-269.e5, 2018 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29395784
14.
The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor.
Structure
; 23(12): 2291-2299, 2015 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26526853