Detalhe da pesquisa
1.
The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock.
Nat Immunol
; 13(11): 1045-1054, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23023391
2.
Long-term treatment of cancer-prone germline PTEN mutant mice with low-dose rapamycin extends lifespan and delays tumour development.
J Pathol
; 258(4): 382-394, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36073856
3.
Oncogenic PIK3CA promotes cellular stemness in an allele dose-dependent manner.
Proc Natl Acad Sci U S A
; 116(17): 8380-8389, 2019 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30948643
4.
Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer.
Nature
; 510(7505): 407-411, 2014 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24919154
5.
Novel Role for p110ß PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells.
PLoS Genet
; 11(7): e1005304, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26132308
6.
Corrigendum: Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer.
Nature
; 535(7613): 580, 2016 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27049952
7.
Inactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice.
Diabetologia
; 59(7): 1503-1512, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27138914
8.
Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration.
Nature
; 453(7195): 662-6, 2008 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-18449193
9.
Polyamine production is downstream and upstream of oncogenic PI3K signalling and contributes to tumour cell growth.
Biochem J
; 450(3): 619-28, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23330613
10.
Factors influencing the successful implementation of a novel digital health application to streamline multidisciplinary communication across multiple organisations for emergency care.
J Eval Clin Pract
; 30(2): 184-198, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37721181
11.
Both p110α and p110ß isoforms of PI3K can modulate the impact of loss-of-function of the PTEN tumour suppressor.
Biochem J
; 442(1): 151-9, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22150431
12.
Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation.
Nature
; 441(7091): 366-70, 2006 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-16625210
13.
Real-world, feasibility study to investigate the use of a multidisciplinary app (Pulsara) to improve prehospital communication and timelines for acute stroke/STEMI care.
BMJ Open
; 12(7): e052332, 2022 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35851025
14.
Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy.
Nat Commun
; 12(1): 117, 2021 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33402692
15.
Essential role for the p110delta phosphoinositide 3-kinase in the allergic response.
Nature
; 431(7011): 1007-11, 2004 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-15496927
16.
Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism.
Nat Commun
; 8(1): 1804, 2017 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29180704
17.
Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.
Nat Commun
; 8(1): 1773, 2017 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29170395
18.
Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans.
Sci Transl Med
; 8(332): 332ra43, 2016 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27030595
19.
Inactivation of the Class II PI3K-C2ß Potentiates Insulin Signaling and Sensitivity.
Cell Rep
; 13(9): 1881-94, 2015 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26655903
20.
Comparing two laryngeal masks: the twin importance of a quantitative measure of the oropharyngeal sealing pressure, and the scrupulous avoidance of an excessive intracuff pressure.
Minerva Anestesiol
; 84(6): 655-657, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29516709