Detalhe da pesquisa
1.
Mitochondria in peroxisome-deficient hepatocytes exhibit impaired respiration, depleted DNA, and PGC-1α independent proliferation.
Biochim Biophys Acta
; 1853(2): 285-98, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25450972
2.
Oral administration of the broad-spectrum antibiofilm compound toremifene inhibits Candida albicans and Staphylococcus aureus biofilm formation in vivo.
Antimicrob Agents Chemother
; 58(12): 7606-10, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25288093
3.
Carbohydrate metabolism is perturbed in peroxisome-deficient hepatocytes due to mitochondrial dysfunction, AMP-activated protein kinase (AMPK) activation, and peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) suppression.
J Biol Chem
; 286(49): 42162-42179, 2011 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22002056
4.
Peroxisome deficient aP2-Pex5 knockout mice display impaired white adipocyte and muscle function concomitant with reduced adrenergic tone.
Mol Genet Metab
; 107(4): 735-47, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23141464
5.
Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells.
Cancer Res
; 67(17): 8180-7, 2007 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17804731
6.
Mitochondrial disruption in peroxisome deficient cells is hepatocyte selective but is not mediated by common hepatic peroxisomal metabolites.
Mitochondrion
; 39: 51-59, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28866057
7.
Stimulation of superoxide production increases fungicidal action of miconazole against Candida albicans biofilms.
Sci Rep
; 6: 27463, 2016 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27272719
8.
2-(2-oxo-morpholin-3-yl)-acetamide derivatives as broad-spectrum antifungal agents.
J Med Chem
; 58(3): 1502-12, 2015 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25585716
9.
Transition-metal-free catalysts for the sustainable epoxidation of alkenes: from discovery to optimisation by means of high throughput experimentation.
Comb Chem High Throughput Screen
; 15(2): 140-51, 2012 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21902643
10.
Gene-targeting of Phd2 improves tumor response to chemotherapy and prevents side-toxicity.
Cancer Cell
; 22(2): 263-77, 2012 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22897855
11.
Lewis acid double metal cyanide catalysts for hydroamination of phenylacetylene.
Chem Commun (Camb)
; 47(14): 4114-6, 2011 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21380422
12.
Hepatosteatosis in peroxisome deficient liver despite increased ß-oxidation capacity and impaired lipogenesis.
Biochimie
; 93(10): 1828-38, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21756965
13.
Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes.
Eur J Pharm Sci
; 43(4): 297-307, 2011 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-21605667
14.
Role of PPARα in Hepatic Carbohydrate Metabolism.
PPAR Res
; 20102010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20936117
15.
Oxidation of cyclic acetals by ozone in ionic liquid media.
Chem Commun (Camb)
; (42): 6439-41, 2009 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-19841802