Detalhe da pesquisa
1.
Mediator kinase inhibition further activates super-enhancer-associated genes in AML.
Nature
; 526(7572): 273-276, 2015 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26416749
2.
NVL-520 Is a Selective, TRK-Sparing, and Brain-Penetrant Inhibitor of ROS1 Fusions and Secondary Resistance Mutations.
Cancer Discov
; 13(3): 598-615, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36511802
3.
The selectivity of austocystin D arises from cell-line-specific drug activation by cytochrome P450 enzymes.
J Nat Prod
; 74(4): 567-73, 2011 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21348461
4.
Use of dynasore, the small molecule inhibitor of dynamin, in the regulation of endocytosis.
Methods Enzymol
; 438: 77-93, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18413242
5.
Biochemical suppression of small-molecule inhibitors: a strategy to identify inhibitor targets and signaling pathway components.
Chem Biol
; 13(4): 443-52, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16632257
6.
STAT3 Inhibitory Activity of Structurally Simplified Withaferin A Analogues.
Org Lett
; 19(7): 1538-1541, 2017 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28350459
7.
Mediator Kinase Phosphorylation of STAT1 S727 Promotes Growth of Neoplasms With JAK-STAT Activation.
EBioMedicine
; 26: 112-125, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29239838
8.
The Cdc42 inhibitor secramine B prevents cAMP-induced K+ conductance in intestinal epithelial cells.
Biochem Pharmacol
; 71(12): 1720-6, 2006 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-16677615
9.
Identification of Mediator Kinase Substrates in Human Cells using Cortistatin A and Quantitative Phosphoproteomics.
Cell Rep
; 15(2): 436-50, 2016 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27050516
10.
Secramine inhibits Cdc42-dependent functions in cells and Cdc42 activation in vitro.
Nat Chem Biol
; 2(1): 39-46, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16408091