Detalhe da pesquisa
1.
Aldo-Keto Reductases and Cancer Drug Resistance.
Pharmacol Rev
; 73(3): 1150-1171, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34312303
2.
Role of Human Aldo-Keto Reductases and Nuclear Factor Erythroid 2-Related Factor 2 in the Metabolic Activation of 1-Nitropyrene via Nitroreduction in Human Lung Cells.
Chem Res Toxicol
; 36(2): 270-280, 2023 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36693016
3.
Germline Mutations in Steroid Metabolizing Enzymes: A Focus on Steroid Transforming Aldo-Keto Reductases.
Int J Mol Sci
; 24(3)2023 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36768194
4.
Using biochemistry and biophysics to extinguish androgen receptor signaling in prostate cancer.
J Biol Chem
; 296: 100240, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33384381
5.
Genetic and epigenetic regulation of the NRF2-KEAP1 pathway in human lung cancer.
Br J Cancer
; 126(9): 1244-1252, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34845361
6.
Identification of spatio-temporal clusters of lung cancer cases in Pennsylvania, USA: 2010-2017.
BMC Cancer
; 22(1): 555, 2022 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35581566
7.
Nitroreduction: A Critical Metabolic Pathway for Drugs, Environmental Pollutants, and Explosives.
Chem Res Toxicol
; 35(10): 1747-1765, 2022 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36044734
8.
Automating Predictive Toxicology Using ComptoxAI.
Chem Res Toxicol
; 35(8): 1370-1382, 2022 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35819939
9.
Role of Human Aldo-Keto Reductases in the Nitroreduction of 1-Nitropyrene and 1,8-Dinitropyrene.
Chem Res Toxicol
; 35(12): 2296-2309, 2022 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36399404
10.
An End Point-Specific Framework for Read-Across Analog Selection for Human Health Effects.
Chem Res Toxicol
; 35(12): 2324-2334, 2022 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36458907
11.
Clustering a Chemical Inventory for Safety Assessment of Fragrance Ingredients: Identifying Read-Across Analogs to Address Data Gaps.
Chem Res Toxicol
; 33(7): 1709-1718, 2020 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32338872
12.
Aldo-keto reductase 1C3-Assessment as a new target for the treatment of endometriosis.
Pharmacol Res
; 152: 104446, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31546014
13.
Induction of the Antioxidant Response by the Transcription Factor NRF2 Increases Bioactivation of the Mutagenic Air Pollutant 3-Nitrobenzanthrone in Human Lung Cells.
Chem Res Toxicol
; 32(12): 2538-2551, 2019 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31746589
14.
On meta- and mega-analyses for gene-environment interactions.
Genet Epidemiol
; 41(8): 876-886, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29110346
15.
Role of Human Aldo-Keto Reductases in the Metabolic Activation of the Carcinogenic Air Pollutant 3-Nitrobenzanthrone.
Chem Res Toxicol
; 31(11): 1277-1288, 2018 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30406992
16.
Aldo-Keto Reductase Regulation by the Nrf2 System: Implications for Stress Response, Chemotherapy Drug Resistance, and Carcinogenesis.
Chem Res Toxicol
; 30(1): 162-176, 2017 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27806574
17.
Potential Metabolic Activation of a Representative C4-Alkylated Polycyclic Aromatic Hydrocarbon Retene (1-Methyl-7-isopropyl-phenanthrene) Associated with the Deepwater Horizon Oil Spill in Human Hepatoma (HepG2) Cells.
Chem Res Toxicol
; 30(4): 1093-1101, 2017 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28278373
18.
Potential Metabolic Activation of Representative Alkylated Polycyclic Aromatic Hydrocarbons 1-Methylphenanthrene and 9-Ethylphenanthrene Associated with the Deepwater Horizon Oil Spill in Human Hepatoma (HepG2) Cells.
Chem Res Toxicol
; 30(12): 2140-2150, 2017 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29035516
19.
Potential Metabolic Activation of a Representative C2-Alkylated Polycyclic Aromatic Hydrocarbon 6-Ethylchrysene Associated with the Deepwater Horizon Oil Spill in Human Hepatoma (HepG2) Cells.
Chem Res Toxicol
; 29(6): 991-1002, 2016 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27054409
20.
Electron transfer by human wild-type and A287P mutant P450 oxidoreductase assessed by transient kinetics: functional basis of P450 oxidoreductase deficiency.
Biochem J
; 468(1): 25-31, 2015 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25728647