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1.
Instr Course Lect ; 72: 577-594, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36534881

RESUMO

Distal radius fractures are one of the most common injuries treated by orthopaedic surgeons. As the number of distal radius fractures grows and practice patterns demonstrate more of these fractures are treated surgically, it is incumbent for orthopaedic surgeons to understand the fundamentals of evaluation, treatment, and rehabilitation.


Assuntos
Fraturas do Rádio , Cirurgiões , Fraturas do Punho , Humanos , Fraturas do Rádio/cirurgia , Fixação de Fratura , Fixação Interna de Fraturas
2.
Int Orthop ; 45(6): 1567-1572, 2021 06.
Artigo em Inglês | MEDLINE | ID: mdl-33877406

RESUMO

AIM OF THE STUDY: Augmented glenoid baseplates are utilized in reverse total shoulder arthroplasty in the setting of glenoid bone loss. These implants permit lateralization of the joint line and correction of bony version abnormalities. To allow bone preservation in the setting of abnormal bony version or deficiency, the backside of the augmented glenoid baseplate is not perpendicular to the axis of the central post/screw. Thus, if the baseplate is implanted with any rotational malposition, this could affect the backside contact area available for ingrowth. The purpose of this study was to assess if rotational malpositioning of a full-wedge augmented baseplate alongside the axis of the central screw significantly affects the glenoid implant backside contact area. METHODS: Seven synthetic scapulas (Sawbones, Vashon, WA) were used to implant a 15° full-wedge glenoid baseplate (Wright Medical, Memphis, TN) according to the manufacturer's technique. The contact pressure between the baseplate and the glenoid surface at rotational positions 5°, 10°, and 15° clockwise (CW) and counterclockwise (CCW) from the central axis was measured with Extreme Low Fujifilm Prescale (Tekscan, Boston, MA). The data was analyzed digitally to obtain a percentage of contact surface area. To evaluate gross contact, a computed tomography (CT) scan was performed and manual measurements of contact between the glenoid and the baseplate were conducted using a standardized axial CT slice. RESULTS: The average contact area at zero degrees of malrotation was 37.26 ± 3.27%. Average contact areas for the simulated malposition cases were 13.99 ± 9.39% at 15° CCW, 24.89 ± 5.11% at 10° CW, and 19.32 ± 3.13% at 15° CW. Each of these results was significant (p < 0.003). On computed tomography, at 15° CCW, the contact area decreased by 39%; at 15° CW, the contact area decreased by 38%. DISCUSSION: The use of augmented glenoid baseplates presents a technical challenge. It is difficult to avoid implant malrotation along the axis of the central peg/screw, because the final rotation of the baseplate must be chosen while the implant is several centimeters away from the bone. This study found that 10° and 15° malrotation about the glenoid baseplate's central axis leads to significant decreases in the implant-bone contact area. CONCLUSIONS: When implanting an augmented baseplate for total shoulder arthroplasty, it is important to minimize baseplate malrotation to decrease the risk of baseplate loosening.


Assuntos
Artroplastia do Ombro , Artroplastia de Substituição , Cavidade Glenoide , Articulação do Ombro , Artroplastia do Ombro/efeitos adversos , Cavidade Glenoide/diagnóstico por imagem , Cavidade Glenoide/cirurgia , Humanos , Escápula/diagnóstico por imagem , Escápula/cirurgia , Articulação do Ombro/diagnóstico por imagem , Articulação do Ombro/cirurgia
3.
Int Orthop ; 45(7): 1767-1774, 2021 07.
Artigo em Inglês | MEDLINE | ID: mdl-34027565

RESUMO

PURPOSE: The rotator cuff (RC) muscles contribute to dynamic stability and rotational actions of the glenohumeral joint. Moment arm can be used to demonstrate the potential work a muscle contributes to a musculoskeletal joint rotation. This study aimed to understand the moment arm contributions of the RC muscles and explore changes following a complete supraspinatus tear treated with either superior capsular reconstruction (SCR) or reverse total shoulder arthroplasty (rTSA). METHODS: Five fresh-frozen cadaveric specimens were prepared and mounted in an apparatus where each intact RC muscle was held in tension with a line of action toward its origin on the scapula. Mean moment arms for each muscle were determined experimentally based on Optotrak data collected during cadaveric shoulder arm abduction. RESULTS: Using ANOVA testing, our analysis demonstrated significant differences (p < 0.001) in infraspinatus and teres minor moment arms after rTSA compared to the intact shoulder model. After SCR, significant differences (p < 0.001) were seen in teres minor, with these differences being statistically similar to the changes seen in teres minor after rTSA. Subscapularis showed no significant difference in moment arm values between the models (p = 0.148). CONCLUSION: Our results illustrate that mean moment arms were preserved in the RC muscles after complete supraspinatus tear. This study also shows evidence that subscapularis function may be maintained after SCR or rTSA. After SCR, infraspinatus may maintain similar abduction ability compared to the anatomical shoulder, while teres minor ability may increase. Infraspinatus may have decreased abduction ability after rTSA while teres minor may have increased ability.


Assuntos
Artroplastia do Ombro , Lesões do Manguito Rotador , Articulação do Ombro , Braço , Fenômenos Biomecânicos , Humanos , Amplitude de Movimento Articular , Manguito Rotador/cirurgia , Lesões do Manguito Rotador/cirurgia , Articulação do Ombro/cirurgia
4.
Am J Ther ; 27(5): e431-e438, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-30277904

RESUMO

BACKGROUND: Newborn infants are highly vulnerable to oxidative stress. Following birth asphyxia, oxidative injury due to ischemia-reperfusion can result in significant brain and heart damage, leading to death or long-term disability. STUDY QUESTION: The study objective was to evaluate the effectiveness of antioxidant gamma-L-glutamyl-L-cysteine (γGlu-Cys) in inhibiting oxidative injury to cultured embryonic cardiomyocytes (H9c2 cells). STUDY DESIGN: Control and γGlu-Cys-treated (0.5 mM) H9c2 cells were incubated under 6-hour ischemic conditions followed by 2-hour simulated reperfusion. MEASURES AND OUTCOMES: To quantify oxidative stress-induced apoptosis sustained by cardiomyocytes, lactate dehydrogenase (LDH) release and the presence of cytosolic cytochrome c were measured, as well as the number of secondary lysosomes visualized under electron microscopy. RESULTS: Compared to controls, H9c2 cells coincubated with γGlu-Cys during ischemia-reperfusion exhibited a significant reduction in both LDH release into the incubation medium [23.88 ± 4.08 (SE) vs. 9.95 ± 1.86% of total; P = 0.02] and the number of secondary lysosomes [0.070 ± 0.009 (SD) vs. 0.043 ± 0.004 per µm; P = 0.01]. Inhibition of LDH release with γGlu-Cys was the same (P = 0.67) as that of a caspase inhibitor. The significant increase in cytosolic cytochrome c (P = 0.01) after ischemia-reperfusion simulation further supports γGlu-Cys's role in apoptosis prevention. CONCLUSIONS: It is concluded that the glutathione precursor γGlu-Cys protects cultured embryonic cardiomyocytes from apoptosis-associated oxidative injury.


Assuntos
Antioxidantes/farmacologia , Asfixia Neonatal/tratamento farmacológico , Dipeptídeos/farmacologia , Traumatismo por Reperfusão Miocárdica/prevenção & controle , Miócitos Cardíacos/efeitos dos fármacos , Animais , Antioxidantes/uso terapêutico , Apoptose/efeitos dos fármacos , Asfixia Neonatal/complicações , Linhagem Celular , Dipeptídeos/uso terapêutico , Modelos Animais de Doenças , Avaliação Pré-Clínica de Medicamentos , Embrião de Mamíferos , Humanos , Recém-Nascido , Traumatismo por Reperfusão Miocárdica/etiologia , Miócitos Cardíacos/patologia , Estresse Oxidativo/efeitos dos fármacos , Ratos
5.
J Shoulder Elbow Surg ; 29(10): 1959-1966, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32669201

RESUMO

BACKGROUND: Superior capsular reconstruction (SCR) has been gaining popularity as a treatment for irreparable rotator cuff tears (RCTs), especially in younger patients. This biomechanical study aimed to investigate how SCR affects functional abduction force, humeral head migration, and passive range of motion following an irreparable RCT. We hypothesized that SCR will restore these parameters to nearly intact shoulder levels. METHODS: Six fresh-frozen cadaveric shoulders were evaluated using a custom biomechanical testing apparatus. Each shoulder was taken through 3 conditions: (1) intact (control); (2) irreparable, complete supraspinatus (SS) tear; and (3) SCR. Functional abduction force, superior humeral head migration, and passive range of motion, including axial shoulder rotation, were measured in static condition at 0°, 30°, and 60° of glenohumeral abduction. Data were analyzed using the paired Student t test or Wilcoxon signed rank test, depending on the results of normality testing. RESULTS: The irreparable SS tear resulted in significantly lower functional abduction force at 30° of abduction (P = .01) and a trend toward a decrease (P = .17) at 60° compared with the intact configuration. SCR shoulders produced greater functional force at 0° compared with the tear configuration (P = .046). Humeral head migration was significantly increased by 4.4 and 3.0 mm at 0° and 30° of abduction, respectively, when comparing the intact vs. SS tear configurations (P = .001). SCR decreased superior migration down to levels of intact shoulders at 0° and 30° of abduction (P = .008 and P = .013, respectively) and was not significantly different from the intact configuration at any angle. SCR decreased passive shoulder extension compared with the tear configuration and increased abduction compared with the intact configuration (P = .007 and P = .03, respectively). The overall arc of axial rotation was not significantly different between SCR and the intact configuration at any angle. CONCLUSIONS: In the setting of an irreparable SS tear, SCR restores key biomechanical parameters of the shoulder to intact levels. SCR should be considered for qualifying patients with irreparable RCTs.


Assuntos
Artroplastia/métodos , Cabeça do Úmero/fisiopatologia , Cápsula Articular/cirurgia , Lesões do Manguito Rotador/cirurgia , Articulação do Ombro/fisiopatologia , Idoso , Fenômenos Biomecânicos , Cadáver , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Movimento , Amplitude de Movimento Articular
6.
Int Orthop ; 44(11): 2371-2377, 2020 11.
Artigo em Inglês | MEDLINE | ID: mdl-32638068

RESUMO

AIM OF THE STUDY: Our objective was to compare biomechanical effects of superior capsular reconstruction (SCR) and reverse total shoulder arthroplasty (rTSA) on shoulder motion, in the setting of an irreparable supraspinatus (SS) tear. We hypothesized that rTSA would produce greater improvement in abduction force and shift the humerus inferiorly, while SCR would produce greater range of motion (ROM) and prevent superior migration of the humerus during abduction. METHODS: Six cadaveric shoulders were evaluated using a custom biomechanical apparatus. Each shoulder underwent four experimental conditions: (1) intact/control, (2) irreparable SS tear, (3) SCR using dermal allograft, and (4) rTSA without SCR. Deltoid abduction force, superior humeral head translation, and passive range of motion were measured in static tendon loading condition at 0, 30, and 60° of glenohumeral abduction. RESULTS: Both rTSA and SCR restored abduction force to intact levels at all abduction angles. rTSA significantly increased abduction force compared with the SS-deficient shoulder at 0, 30, 60° (p = 0.04), while SCR produced a significant increase at 0° (p = 0.05) abduction. rTSA inferiorly shifted the humeral head by 27 mm (p = 0.002). SCR restored superior humeral head translation to intact SS levels. Compared with SCR, rTSA resulted in 25° less passive abduction (p = 0.001) without significant differences in forward flexion/extension. Compared with SCR, rTSA achieved 10° less passive internal rotation at 0° abduction (p = 0.03) and 26° and 17° greater external rotation at 30° and 60° abduction, respectively (p = 0.03, p = 0.04). DISCUSSION: Our investigation found that abduction force was restored to intact cuff levels by both procedures, without significant differences between the two techniques. SCR restored superior humeral head migration and rTSA translated the humerus inferiorly. rTSA resulted in decreased passive abduction ROM and increased external rotation, compared with SCR. CONCLUSION: Both SCR and rTSA restore key biomechanical parameters following an irreparable SS tear, although SCR offers superior passive abduction ROM.


Assuntos
Artroplastia do Ombro , Lesões do Manguito Rotador , Articulação do Ombro , Fenômenos Biomecânicos , Cadáver , Humanos , Amplitude de Movimento Articular , Manguito Rotador/cirurgia , Lesões do Manguito Rotador/cirurgia , Ombro , Articulação do Ombro/cirurgia
7.
Orthop J Sports Med ; 8(12): 2325967120964476, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-33330732

RESUMO

BACKGROUND: Degenerative and traumatic changes to the rotator cuff can result in massive and irreparable rotator cuff tears (RCTs). PURPOSE/HYPOTHESIS: The study objective was to conduct a biomechanical comparison between a small, incomplete RCT and a large, complete RCT. We hypothesized that the incomplete supraspinatus (SS) tear would lead to an incremental loss of abduction force and preserve vertical position of the humeral head, while a complete SS tear would cause superior humeral migration, decrease functional deltoid abduction force, and increase passive range of motion (ROM). STUDY DESIGN: Controlled laboratory study. METHODS: Six cadaveric shoulders were evaluated using a custom testing apparatus. Each shoulder was subjected to 3 conditions: (1) intact/control, (2) 50%, full-thickness, incomplete SS tear, and (3) 100%, complete SS tear. Deltoid abduction force, superior humeral head migration, and passive ROM were measured in static conditions at 0°, 30°, and 60° of glenohumeral abduction, respectively. RESULTS: The intact SS resulted in a mean deltoid abduction force of 2.5, 3.3, and 3.8 N at 0°, 30°, and 60° of abduction, respectively. Compared with the intact shoulder, there was no significant difference in mean abduction force seen in the incomplete tear, while the force was significantly decreased by 52% at 30° of abduction in the complete tear (P = .009). Compared with the incomplete tear, there were significant decreases in abduction force seen in the complete tear, by 33% and 48% (0.9 N and 1.1 N) at 0° and 30° of abduction, respectively (P = .04 and .004). The intact configuration experienced a mean superior humeral head migration of 1.5, 1.4, and 1.1 mm at 0°, 30°, and 60° of abduction, respectively. The complete tear resulted in a superior migration of 3.0 and 4.4 mm greater than the intact configuration at 0° and 30° of abduction, respectively (P = .001). There was a 5° and 10° increase in abduction ROM with 50% and 100% tears, respectively (P = .003 and .03). CONCLUSION: An incomplete SS tear does not significantly alter the biomechanics of the shoulder, while a large, complete SS tear leads to a significant superior humeral migration, a decreased deltoid abduction force, and a mild increase in passive ROM. CLINICAL RELEVANCE: Our findings demonstrate the effects of large SS tears on key biomechanical parameters, as they progress from partial tears.

8.
Orthop J Sports Med ; 7(6): 2325967119848667, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31218236

RESUMO

BACKGROUND: Previous studies have aimed to biomechanically improve the transosseous tunnel technique of rotator cuff repair. However, no previous work has addressed tunnel inclination at the time of surgery as an influence on the strength of the repair construct. HYPOTHESIS: We hypothesized that the tunnel angle and entry point would influence the biomechanical strength of the transosseous tunnel in rotator cuff repair. Additionally, we investigated how tunnel length and bone quality affect the strength of the repair construct. STUDY DESIGN: Controlled laboratory study. METHODS: Mechanical testing was performed on 10 cadaveric humeri. Variations in the bone tunnel angle were imposed in the supraspinatus footprint to create lateral tunnels with inclinations of 30°, 45°, and 90° relative to the longitudinal axis of the humeral shaft. A closed loop of suture was passed through the bone tunnel, and cyclic loading was applied until failure of the construct. Load to failure and distance between entry points were the dependent variables. Analysis of variance, post hoc paired t tests, and the Bonferroni correction were used to analyze the relationship between the tunnel angle and failure load. The Pearson correlation coefficient was then used to evaluate the correlation of the distance between entry points to the ultimate failure load, and t tests were used to compare failure loads between healthy and osteoporotic bone. RESULTS: Tunnels drilled perpendicularly to the longitudinal axis (90°) achieved the highest mean failure load (167.51 ± 48.35 N). However, there were no significant differences in the failure load among the 3 tested inclinations. Tunnels drilled perpendicularly to the longitudinal axis (90°) measured 13.86 ± 1.35 mm between entry points and were significantly longer (P = .03) than the tunnels drilled at 30° and 45°. We found no correlation of the distance between entry points and the ultimate failure load. Within the scope of this study, we could not identify a significant effect of bone quality on failure load. CONCLUSION: The tunnel angle does not influence the strength of the bone-suture interface in the transosseous rotator cuff repair construct. CLINICAL RELEVANCE: The transosseous technique has gained popularity in recent years, given its arthroscopic use. These findings suggest that surgeons should not focus on the tunnel angle as they seek to maximize repair strength.

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