Detalhe da pesquisa
1.
Inflammatory bowel disease induces pathological α-synuclein aggregation in the human gut and brain.
Neuropathol Appl Neurobiol
; 50(1): e12962, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38343067
2.
Neuromelanin accumulation drives endogenous synucleinopathy in non-human primates.
Brain
; 146(12): 5000-5014, 2023 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37769648
3.
Boolean analysis shows a high proportion of dopamine D2 receptors interacting with adenosine A2A receptors in striatal medium spiny neurons of mouse and non-human primate models of Parkinson's disease.
Neurobiol Dis
; 188: 106341, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37918757
4.
AT1 receptor autoantibodies mediate effects of metabolic syndrome on dopaminergic vulnerability.
Brain Behav Immun
; 108: 255-268, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36535607
5.
Microglial angiotensin type 2 receptors mediate sex-specific expression of inflammatory cytokines independently of circulating estrogen.
Glia
; 70(12): 2348-2360, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35943203
6.
Diabetes, insulin and new therapeutic strategies for Parkinson's disease: Focus on glucagon-like peptide-1 receptor agonists.
Front Neuroendocrinol
; 62: 100914, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33845041
7.
SARS-CoV-2 as a Factor to Disbalance the Renin-Angiotensin System: A Suspect in the Case of Exacerbated IL-6 Production.
J Immunol
; 205(5): 1198-1206, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32680957
8.
Autoantibodies against ACE2 and angiotensin type-1 receptors increase severity of COVID-19.
J Autoimmun
; 122: 102683, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34144328
9.
Experimental data using candesartan and captopril indicate no double-edged sword effect in COVID-19.
Clin Sci (Lond)
; 135(3): 465-481, 2021 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33479758
10.
Glucocerebrosidase Gene Therapy Induces Alpha-Synuclein Clearance and Neuroprotection of Midbrain Dopaminergic Neurons in Mice and Macaques.
Int J Mol Sci
; 22(9)2021 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34062940
11.
Angiotensin AT1 and AT2 receptor heteromer expression in the hemilesioned rat model of Parkinson's disease that increases with levodopa-induced dyskinesia.
J Neuroinflammation
; 17(1): 243, 2020 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32807174
12.
Angiotensin type 2 receptors: Role in aging and neuroinflammation in the substantia nigra.
Brain Behav Immun
; 87: 256-271, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31863823
13.
Functional Complexes of Angiotensin-Converting Enzyme 2 and Renin-Angiotensin System Receptors: Expression in Adult but Not Fetal Lung Tissue.
Int J Mol Sci
; 21(24)2020 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33339432
14.
Receptor-heteromer mediated regulation of endocannabinoid signaling in activated microglia. Role of CB1 and CB2 receptors and relevance for Alzheimer's disease and levodopa-induced dyskinesia.
Brain Behav Immun
; 67: 139-151, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28843453
15.
Menopause and Parkinson's disease. Interaction between estrogens and brain renin-angiotensin system in dopaminergic degeneration.
Front Neuroendocrinol
; 43: 44-59, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27693730
16.
Dopamine modulates astroglial and microglial activity via glial renin-angiotensin system in cultures.
Brain Behav Immun
; 62: 277-290, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28232171
17.
Interaction between NADPH-oxidase and Rho-kinase in angiotensin II-induced microglial activation.
Glia
; 63(3): 466-82, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25377425
18.
Microglial TNF-α mediates enhancement of dopaminergic degeneration by brain angiotensin.
Glia
; 62(1): 145-57, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24272709
19.
The role of the brain renin-angiotensin system in Parkinson´s disease.
Transl Neurodegener
; 13(1): 22, 2024 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38622720
20.
Angiotensin type 1 receptor activation promotes neuronal and glial alpha-synuclein aggregation and transmission.
NPJ Parkinsons Dis
; 10(1): 37, 2024 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38368444